Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 11 to 20 of 46

Publication Record

Connections

NF-κB inducing kinase (NIK) modulates melanoma tumorigenesis by regulating expression of pro-survival factors through the β-catenin pathway.
Thu YM, Su Y, Yang J, Splittgerber R, Na S, Boyd A, Mosse C, Simons C, Richmond A
(2012) Oncogene 31: 2580-92
MeSH Terms: Animals, Apoptosis, Cell Line, Tumor, Cell Proliferation, Cell Survival, Cyclin D2, Down-Regulation, Enzyme Activation, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Genes, bcl-2, Genes, myc, Humans, Melanoma, Melanoma, Experimental, Mice, Neoplasm Metastasis, Protein-Serine-Threonine Kinases, RNA, Small Interfering, Signal Transduction, beta Catenin
Added June 14, 2013
2 Communities
2 Members
0 Resources
21 MeSH Terms
Impact of hydrodynamic injection and phiC31 integrase on tumor latency in a mouse model of MYC-induced hepatocellular carcinoma.
Woodard LE, Keravala A, Jung WE, Wapinski OL, Yang Q, Felsher DW, Calos MP
(2010) PLoS One 5: e11367
MeSH Terms: Animals, Base Sequence, Carcinoma, Hepatocellular, DNA Primers, Female, Genes, myc, Integrases, Liver Neoplasms, Experimental, Male, Mice, Mice, Transgenic
Added December 8, 2017
0 Communities
1 Members
0 Resources
11 MeSH Terms
MicroRNA biogenesis is required for Myc-induced B-cell lymphoma development and survival.
Arrate MP, Vincent T, Odvody J, Kar R, Jones SN, Eischen CM
(2010) Cancer Res 70: 6083-92
MeSH Terms: Alleles, Animals, Cell Transformation, Neoplastic, DEAD-box RNA Helicases, Endoribonucleases, Gene Deletion, Genes, myc, Genes, p53, Lymphoma, B-Cell, Mice, Mice, Knockout, MicroRNAs, Ribonuclease III
Added March 5, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
A deficiency in Mdm2 binding protein inhibits Myc-induced B-cell proliferation and lymphomagenesis.
Odvody J, Vincent T, Arrate MP, Grieb B, Wang S, Garriga J, Lozano G, Iwakuma T, Haines DS, Eischen CM
(2010) Oncogene 29: 3287-96
MeSH Terms: Animals, Apoptosis, B-Lymphocytes, Carrier Proteins, Cell Growth Processes, Cells, Cultured, Female, Genes, Tumor Suppressor, Genes, myc, Humans, Lymphoma, B-Cell, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Proto-Oncogene Proteins c-mdm2, Tumor Suppressor Protein p53
Added March 5, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Ligand-independent phosphorylation of Y869 (Y845) links mutant EGFR signaling to stat-mediated gene expression.
Yang S, Park K, Turkson J, Arteaga CL
(2008) Exp Cell Res 314: 413-9
MeSH Terms: ErbB Receptors, Erlotinib Hydrochloride, Genes, myc, Humans, Ligands, Mutation, Phosphorylation, Proto-Oncogene Proteins pp60(c-src), Quinazolines, STAT5 Transcription Factor, Signal Transduction, Tumor Cells, Cultured
Added March 5, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants.
Hemann MT, Bric A, Teruya-Feldstein J, Herbst A, Nilsson JA, Cordon-Cardo C, Cleveland JL, Tansey WP, Lowe SW
(2005) Nature 436: 807-11
MeSH Terms: Adoptive Transfer, Alleles, Animals, Apoptosis, Apoptosis Regulatory Proteins, Bcl-2-Like Protein 11, Burkitt Lymphoma, Carrier Proteins, Cell Cycle Proteins, Cell Proliferation, Cyclin-Dependent Kinase Inhibitor p16, Cyclin-Dependent Kinase Inhibitor p21, Genes, myc, Humans, Membrane Proteins, Mice, Mice, Inbred C57BL, Mutation, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-bcl-2, Proto-Oncogene Proteins c-myc, Stem Cell Transplantation, Tumor Suppressor Protein p14ARF, Tumor Suppressor Protein p53
Added March 10, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
Disruption of Rb/E2F pathway results in increased cyclooxygenase-2 expression and activity in prostate epithelial cells.
Davis JN, McCabe MT, Hayward SW, Park JM, Day ML
(2005) Cancer Res 65: 3633-42
MeSH Terms: Animals, Cell Cycle Proteins, Cell Line, Cyclooxygenase 2, DNA-Binding Proteins, Dinoprostone, E2F Transcription Factors, E2F1 Transcription Factor, Enzyme Activation, Epithelial Cells, Gene Expression Regulation, Enzymologic, Genes, myc, Male, Mice, Promoter Regions, Genetic, Prostaglandin-Endoperoxide Synthases, Prostate, RNA, Messenger, Retinoblastoma Protein, Transcription Factors, Transcriptional Activation, Up-Regulation
Added December 10, 2013
0 Communities
1 Members
0 Resources
22 MeSH Terms
NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter.
Huth JR, Yu L, Collins I, Mack J, Mendoza R, Isaac B, Braddock DT, Muchmore SW, Comess KM, Fesik SW, Clore GM, Levens D, Hajduk PJ
(2004) J Med Chem 47: 4851-7
MeSH Terms: Binding Sites, Combinatorial Chemistry Techniques, DNA Helicases, DNA, Single-Stranded, DNA-Binding Proteins, Drug Design, Genes, myc, Humans, Inhibitory Concentration 50, Ligands, Magnetic Resonance Spectroscopy, Models, Molecular, Promoter Regions, Genetic, Protein Conformation, Protein Structure, Tertiary, RNA-Binding Proteins, Repetitive Sequences, Amino Acid, Structure-Activity Relationship
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Growth suppression by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc expression.
McConnell MJ, Chevallier N, Berkofsky-Fessler W, Giltnane JM, Malani RB, Staudt LM, Licht JD
(2003) Mol Cell Biol 23: 9375-88
MeSH Terms: Apoptosis, Base Sequence, Binding Sites, Cell Cycle, Cell Division, Chromosomes, Human, Pair 11, Chromosomes, Human, Pair 17, DNA, Complementary, DNA-Binding Proteins, Gene Expression, Genes, myc, Humans, Kruppel-Like Transcription Factors, Leukemia, Promyelocytic, Acute, Promoter Regions, Genetic, Promyelocytic Leukemia Zinc Finger Protein, Repressor Proteins, Transcription Factors, Translocation, Genetic, U937 Cells
Added March 5, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis.
Alt JR, Greiner TC, Cleveland JL, Eischen CM
(2003) EMBO J 22: 1442-50
MeSH Terms: Animals, Apoptosis, B-Lymphocytes, Cell Survival, Cells, Cultured, Gene Expression Regulation, Neoplastic, Genes, Tumor Suppressor, Genes, myc, Genes, p53, Longevity, Lymphoma, B-Cell, Mice, Mice, Knockout, Mice, Transgenic, Neoplasm Proteins, Nuclear Proteins, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-mdm2
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms