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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 34

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EGFR mutant lung adenocarcinomas in patients with germline BRCA mutations.
Marks JL, Golas B, Kirchoff T, Miller VA, Riely GJ, Offit K, Pao W
(2008) J Thorac Oncol 3: 805
MeSH Terms: Adenocarcinoma, Aged, Breast Neoplasms, ErbB Receptors, Frameshift Mutation, Genes, BRCA2, Germ-Line Mutation, Humans, Lung Neoplasms, Male, Middle Aged, Pedigree
Added March 24, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Bulge migration of the malondialdehyde OPdG DNA adduct when placed opposite a two-base deletion in the (CpG)3 frameshift hotspot of the Salmonella typhimurium hisD3052 gene.
Wang Y, Schnetz-Boutaud NC, Saleh S, Marnett LJ, Stone MP
(2007) Chem Res Toxicol 20: 1200-10
MeSH Terms: Base Pairing, CpG Islands, DNA Adducts, DNA-Binding Proteins, Deoxyguanosine, Frameshift Mutation, Genes, Bacterial, Histidine, Magnetic Resonance Spectroscopy, Malondialdehyde, Salmonella typhimurium, Time Factors
Added March 5, 2014
0 Communities
2 Members
0 Resources
12 MeSH Terms
Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4.
Zang H, Irimia A, Choi JY, Angel KC, Loukachevitch LV, Egli M, Guengerich FP
(2006) J Biol Chem 281: 2358-72
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Base Sequence, Chromatography, Liquid, DNA, DNA Primers, DNA-Directed DNA Polymerase, Deoxycytosine Nucleotides, Deoxyguanosine, Dose-Response Relationship, Drug, Escherichia coli, Frameshift Mutation, Kinetics, Mass Spectrometry, Models, Molecular, Molecular Sequence Data, Protein Binding, Sulfolobus solfataricus, Time Factors, X-Ray Diffraction
Added March 5, 2014
0 Communities
2 Members
0 Resources
19 MeSH Terms
DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and frameshift products with the adduct 1,N2-ethenoguanine.
Zang H, Goodenough AK, Choi JY, Irimia A, Loukachevitch LV, Kozekov ID, Angel KC, Rizzo CJ, Egli M, Guengerich FP
(2005) J Biol Chem 280: 29750-64
MeSH Terms: Binding Sites, Crystallography, X-Ray, DNA Adducts, DNA Polymerase beta, DNA Primers, Frameshift Mutation, Guanine, Mass Spectrometry, Sulfolobus solfataricus
Added March 5, 2014
0 Communities
3 Members
0 Resources
9 MeSH Terms
Site-specific synthesis and properties of oligonucleotides containing C8-deoxyguanosine adducts of the dietary mutagen IQ.
Elmquist CE, Stover JS, Wang Z, Rizzo CJ
(2004) J Am Chem Soc 126: 11189-201
MeSH Terms: Amines, Circular Dichroism, Deoxyguanosine, Frameshift Mutation, Mutagens, Oligonucleotides, Quinolines, Spectrophotometry, Ultraviolet
Added January 7, 2016
0 Communities
1 Members
0 Resources
8 MeSH Terms
Mapping of sudden infant death with dysgenesis of the testes syndrome (SIDDT) by a SNP genome scan and identification of TSPYL loss of function.
Puffenberger EG, Hu-Lince D, Parod JM, Craig DW, Dobrin SE, Conway AR, Donarum EA, Strauss KA, Dunckley T, Cardenas JF, Melmed KR, Wright CA, Liang W, Stafford P, Flynn CR, Morton DH, Stephan DA
(2004) Proc Natl Acad Sci U S A 101: 11689-94
MeSH Terms: Active Transport, Cell Nucleus, Adult, Chromosome Mapping, DNA-Binding Proteins, Family Health, Female, Frameshift Mutation, Genome, Human, Gonadal Dysgenesis, Humans, Infant, Male, Nuclear Proteins, Nucleosomes, Pedigree, Sex-Determining Region Y Protein, Sudden Infant Death, Transcription Factors
Added December 10, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
Induction of frameshift and base pair substitution mutations by the major DNA adduct of the endogenous carcinogen malondialdehyde.
VanderVeen LA, Hashim MF, Shyr Y, Marnett LJ
(2003) Proc Natl Acad Sci U S A 100: 14247-52
MeSH Terms: Animals, Base Sequence, COS Cells, Carcinogens, Chlorocebus aethiops, DNA, DNA Adducts, DNA, Bacterial, Escherichia coli, Frameshift Mutation, Mutagens, Point Mutation, Purines, Pyrimidines
Added March 5, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Structure of the malondialdehyde deoxyguanosine adduct M1G when placed opposite a two-base deletion in the (CpG)3 frameshift hotspot of the Salmonella typhimurium hisD3052 gene.
Schnetz-Boutaud NC, Saleh S, Marnett LJ, Stone MP
(2001) Adv Exp Med Biol 500: 513-6
MeSH Terms: Base Pairing, CpG Islands, DNA Adducts, DNA, Bacterial, Deoxyguanosine, Frameshift Mutation, Genes, Bacterial, Mutagenesis, Nucleic Acid Conformation, Salmonella typhimurium
Added March 5, 2014
0 Communities
2 Members
0 Resources
10 MeSH Terms
The exocyclic 1,N2-deoxyguanosine pyrimidopurinone M1G is a chemically stable DNA adduct when placed opposite a two-base deletion in the (CpG)3 frameshift hotspot of the Salmonella typhimurium hisD3052 gene.
Schnetz-Boutaud NC, Saleh S, Marnett LJ, Stone MP
(2001) Biochemistry 40: 15638-49
MeSH Terms: Alcohol Oxidoreductases, Bacterial Proteins, CpG Islands, DNA Adducts, DNA, Bacterial, Deoxyguanosine, Drug Stability, Frameshift Mutation, Genes, Bacterial, Malondialdehyde, Nuclear Magnetic Resonance, Biomolecular, Oligodeoxyribonucleotides, Protons, Salmonella typhimurium, Sequence Deletion, Thermodynamics, Trinucleotide Repeats
Added March 5, 2014
0 Communities
2 Members
0 Resources
17 MeSH Terms
Solution structure of an oligodeoxynucleotide containing the malondialdehyde deoxyguanosine adduct N2-(3-oxo-1-propenyl)-dG (ring-opened M1G) positioned in a (CpG)3 frameshift hotspot of the Salmonella typhimurium hisD3052 gene.
Mao H, Reddy GR, Marnett LJ, Stone MP
(1999) Biochemistry 38: 13491-501
MeSH Terms: Alcohol Oxidoreductases, Bacterial Proteins, CpG Islands, DNA Adducts, DNA, Bacterial, Deoxyguanosine, Frameshift Mutation, Genes, Bacterial, Malondialdehyde, Models, Molecular, Nuclear Magnetic Resonance, Biomolecular, Oligodeoxyribonucleotides, Protons, Purines, Pyrimidine Nucleosides, Pyrimidines, Salmonella typhimurium, Solutions, Thermodynamics
Added March 5, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms