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Results: 11 to 20 of 24

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Intrinsic pathway of coagulation and arterial thrombosis.
Gailani D, Renné T
(2007) Arterioscler Thromb Vasc Biol 27: 2507-13
MeSH Terms: Animals, Anticoagulants, Blood Coagulation, Disease Models, Animal, Factor XI, Factor XI Deficiency, Factor XII, Factor XII Deficiency, Fibrin, Hemostasis, Humans, Infarction, Middle Cerebral Artery, Mice, Mice, Knockout, Protease Inhibitors, Reperfusion Injury, Thromboembolism, Thrombosis
Added May 19, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Effects of factor XI deficiency on ferric chloride-induced vena cava thrombosis in mice.
Wang X, Smith PL, Hsu MY, Gailani D, Schumacher WA, Ogletree ML, Seiffert DA
(2006) J Thromb Haemost 4: 1982-8
MeSH Terms: Animals, Chlorides, Disease Models, Animal, Factor XI Deficiency, Ferric Compounds, Fibrinolysis, Fibrinolytic Agents, Mice, Venae Cavae, Venous Thrombosis
Added May 19, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis.
Kleinschnitz C, Stoll G, Bendszus M, Schuh K, Pauer HU, Burfeind P, Renné C, Gailani D, Nieswandt B, Renné T
(2006) J Exp Med 203: 513-8
MeSH Terms: Animals, Blood Coagulation Factor Inhibitors, Blood Vessels, Brain Ischemia, Factor XI Deficiency, Factor XII, Factor XII Deficiency, Female, Fibrin, Hemostasis, Male, Mice, Mice, Knockout, Thrombosis
Added May 19, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice.
Wang X, Cheng Q, Xu L, Feuerstein GZ, Hsu MY, Smith PL, Seiffert DA, Schumacher WA, Ogletree ML, Gailani D
(2005) J Thromb Haemost 3: 695-702
MeSH Terms: Animals, Arteries, Aspirin, Bleeding Time, Blood Flow Velocity, Carotid Arteries, Carotid Artery Diseases, Chlorides, Dose-Response Relationship, Drug, Factor IX, Factor XI, Factor XI Deficiency, Ferric Compounds, Genotype, Hemophilia B, Heparin, Homozygote, Mice, Mice, Inbred C57BL, Platelet Aggregation, Regional Blood Flow, Thrombosis, Time Factors
Added May 19, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
A classification system for cross-reactive material-negative factor XI deficiency.
Kravtsov DV, Monahan PE, Gailani D
(2005) Blood 105: 4671-3
MeSH Terms: Adult, Alleles, Animals, Blotting, Western, Cell Line, Cricetinae, DNA, Dimerization, Exons, Factor XI, Factor XI Deficiency, Female, Fibroblasts, Genes, Dominant, Heterozygote, Humans, Male, Models, Biological, Mutation, Peptides, Point Mutation, Sequence Analysis, DNA, Transfection
Added May 19, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Severe factor XI deficiency caused by a Gly555 to Glu mutation (factor XI-Glu555): a cross-reactive material positive variant defective in factor IX activation.
Zivelin A, Ogawa T, Bulvik S, Landau M, Toomey JR, Lane J, Seligsohn U, Gailani D
(2004) J Thromb Haemost 2: 1782-9
MeSH Terms: Antithrombin III, Binding Sites, Factor IX, Factor XI, Factor XI Deficiency, Homozygote, Humans, Kinetics, Models, Molecular, Mutation, Missense, Protein Binding, Static Electricity
Added May 19, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Dominant factor XI deficiency caused by mutations in the factor XI catalytic domain.
Kravtsov DV, Wu W, Meijers JC, Sun MF, Blinder MA, Dang TP, Wang H, Gailani D
(2004) Blood 104: 128-34
MeSH Terms: Adult, Amino Acid Substitution, Animals, Catalytic Domain, Cell Line, Coleoptera, Dimerization, Factor XI, Factor XI Deficiency, Fibroblasts, Gene Expression, Genes, Dominant, Heterozygote, Humans, Intracellular Space, Luciferases, Male, Middle Aged, Pedigree, Prekallikrein, Recombinant Proteins, Transfection
Added May 19, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Defective binding of factor XI-N248 to activated human platelets.
Sun MF, Baglia FA, Ho D, Martincic D, Ware RE, Walsh PN, Gailani D
(2001) Blood 98: 125-9
MeSH Terms: Amino Acid Substitution, Blood Platelets, Cells, Cultured, Chromogenic Compounds, Factor IX, Factor XI, Factor XI Deficiency, Fibroblasts, Humans, Kinetics, Protein Binding, Recombinant Proteins, Thrombin
Added May 19, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Gene targeting in hemostasis. factor XI.
Gailani D
(2001) Front Biosci 6: D201-7
MeSH Terms: Animals, Animals, Newborn, Cardiovascular Diseases, Factor XI, Factor XI Deficiency, Gene Targeting, Hemostasis, Humans, Liver, Mice, Mutation, Phenotype
Added May 19, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
The characterization of mice with a targeted combined deficiency of protein c and factor XI.
Chan JC, Ganopolsky JG, Cornelissen I, Suckow MA, Sandoval-Cooper MJ, Brown EC, Noria F, Gailani D, Rosen ED, Ploplis VA, Castellino FJ
(2001) Am J Pathol 158: 469-79
MeSH Terms: Animals, Animals, Newborn, Crosses, Genetic, Embryo, Mammalian, Embryonic and Fetal Development, Factor XI, Factor XI Deficiency, Female, Fibrin, Genotype, Interleukin-6, Liver, Lung, Lymph Nodes, Male, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Microscopy, Electron, Mutation, Myocardium, Plasminogen Activator Inhibitor 1, Pregnancy, Protein C, Protein C Deficiency, Solubility, Tumor Necrosis Factor-alpha
Added May 19, 2014
0 Communities
1 Members
0 Resources
27 MeSH Terms