Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation.
Hermanson DJ, Hartley ND, Gamble-George J, Brown N, Shonesy BC, Kingsley PJ, Colbran RJ, Reese J, Marnett LJ, Patel S
(2013) Nat Neurosci 16
: 1291-8MeSH Terms: Adaptation, Ocular, Amidohydrolases, Animals, Anxiety, Benzoxazines, Body Temperature, Calcium Channel Blockers, Cannabinoid Receptor Agonists, Cannabinoid Receptor Antagonists, Cyclooxygenase 2, Cyclooxygenase Inhibitors, Disease Models, Animal, Endocannabinoids, Exploratory Behavior, Freezing Reaction, Cataleptic, Humans, Indoles, Male, Maze Learning, Mice, Mice, Inbred ICR, Mice, Knockout, Morpholines, Naphthalenes, Receptor, Cannabinoid, CB1, Signal TransductionAdded March 7, 2014
26 MeSH Terms
Paradoxical tolerance to cocaine after initial supersensitivity in drug-use-prone animals.
Ferris MJ, Calipari ES, Melchior JR, Roberts DC, España RA, Jones SR
(2013) Eur J Neurosci 38
: 2628-36MeSH Terms: Animals, Cocaine, Dopamine, Dopamine Uptake Inhibitors, Drug Tolerance, Electrochemical Techniques, Exploratory Behavior, Male, Rats, Rats, Sprague-Dawley, Self AdministrationAdded March 30, 2020
GLP-1 analog attenuates cocaine reward.
Graham DL, Erreger K, Galli A, Stanwood GD
(2013) Mol Psychiatry 18
: 961-2MeSH Terms: Animals, Brain, Cocaine-Related Disorders, Conditioning, Operant, Disease Models, Animal, Dose-Response Relationship, Drug, Exenatide, Exploratory Behavior, Glucagon-Like Peptide 1, Male, Mice, Mice, Inbred C57BL, Peptides, Reward, VenomsAdded February 19, 2015
15 MeSH Terms
The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress.
Hartmann J, Wagner KV, Liebl C, Scharf SH, Wang XD, Wolf M, Hausch F, Rein T, Schmidt U, Touma C, Cheung-Flynn J, Cox MB, Smith DF, Holsboer F, Müller MB, Schmidt MV
(2012) Neuropharmacology 62
: 332-9MeSH Terms: Analysis of Variance, Animals, Corticosterone, Disease Models, Animal, Exploratory Behavior, Gene Expression Regulation, HSP90 Heat-Shock Proteins, Locomotion, Male, Maze Learning, Mice, Mice, Knockout, Neurosecretory Systems, Receptors, Glucocorticoid, Receptors, Mineralocorticoid, Stress, Psychological, Swimming, Tacrolimus Binding ProteinsAdded March 9, 2015
18 MeSH Terms
Genetic, pharmacological and lesion analyses reveal a selective role for corticohippocampal GLUN2B in a novel repeated swim stress paradigm.
Kiselycznyk C, Svenningsson P, Delpire E, Holmes A
(2011) Neuroscience 193
: 259-68MeSH Terms: Analysis of Variance, Animals, Cerebral Cortex, Corticosterone, Dark Adaptation, Disease Models, Animal, Excitatory Amino Acid Antagonists, Exploratory Behavior, Feeding Behavior, Fever, Food Preferences, Hindlimb Suspension, Hippocampus, Immobility Response, Tonic, Mice, Mice, Inbred C57BL, Mice, Transgenic, Neural Pathways, Phenols, Piperidines, Radioimmunoassay, Receptors, AMPA, Receptors, N-Methyl-D-Aspartate, Stress, Psychological, Sucrose, Swimming, Time FactorsAdded November 25, 2014
27 MeSH Terms
Stress-induced alterations in anxiety-like behavior and adaptations in plasticity in the bed nucleus of the stria terminalis.
Conrad KL, Louderback KM, Gessner CP, Winder DG
(2011) Physiol Behav 104
: 248-56MeSH Terms: Adaptation, Physiological, Analysis of Variance, Animals, Anxiety, Behavior, Animal, Biophysics, Corticosterone, Disease Models, Animal, Electric Stimulation, Exploratory Behavior, In Vitro Techniques, Long-Term Potentiation, Male, Maze Learning, Mice, Mice, Inbred C57BL, Patch-Clamp Techniques, Septal Nuclei, Social Isolation, Time FactorsAdded May 19, 2014
20 MeSH Terms
Absence of preference for social novelty and increased grooming in integrin β3 knockout mice: initial studies and future directions.
Carter MD, Shah CR, Muller CL, Crawley JN, Carneiro AM, Veenstra-VanderWeele J
(2011) Autism Res 4
: 57-67MeSH Terms: Animals, Brain, Child, Child Development Disorders, Pervasive, Choice Behavior, Disease Models, Animal, Exploratory Behavior, Grooming, Humans, Integrin beta3, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Motor Activity, Phenotype, Quantitative Trait Loci, Serotonin, Social Behavior, Social Environment, Stereotyped BehaviorAdded February 12, 2015
21 MeSH Terms
Behavioral analysis of Ste20 kinase SPAK knockout mice.
Geng Y, Byun N, Delpire E
(2010) Behav Brain Res 208
: 377-82MeSH Terms: Acoustic Stimulation, Adaptation, Physiological, Animals, Behavior, Animal, Exploratory Behavior, Functional Laterality, Hindlimb Suspension, Hyperalgesia, Mice, Mice, Knockout, Muscle Strength, Pain Measurement, Pain Threshold, Phenotype, Protein Serine-Threonine Kinases, Psychomotor Performance, Reflex, Startle, Statistics, Nonparametric, SwimmingAdded November 25, 2014
19 MeSH Terms
Vitamin C deficiency increases basal exploratory activity but decreases scopolamine-induced activity in APP/PSEN1 transgenic mice.
Harrison FE, May JM, McDonald MP
(2010) Pharmacol Biochem Behav 94
: 543-52MeSH Terms: Amyloid, Amyloid beta-Protein Precursor, Animals, Ascorbic Acid, Ascorbic Acid Deficiency, Brain, Exploratory Behavior, Female, L-Gulonolactone Oxidase, Lipid Peroxidation, Male, Maze Learning, Mice, Mice, Transgenic, Oxidative Stress, Presenilin-1, Survival RateAdded December 10, 2013
17 MeSH Terms
Impaired cognition, sensorimotor gating, and hippocampal long-term depression in mice lacking the prostaglandin E2 EP2 receptor.
Savonenko A, Munoz P, Melnikova T, Wang Q, Liang X, Breyer RM, Montine TJ, Kirkwood A, Andreasson K
(2009) Exp Neurol 217
: 63-73MeSH Terms: Analysis of Variance, Animals, Attention, Avoidance Learning, Choline O-Acetyltransferase, Cognition Disorders, Dendrites, Discrimination, Psychological, Disks Large Homolog 4 Protein, Electroshock, Exploratory Behavior, Guanylate Kinases, Hippocampus, In Vitro Techniques, Inhibition, Psychological, Intracellular Signaling Peptides and Proteins, Long-Term Synaptic Depression, Maze Learning, Membrane Proteins, Memory, Mice, Mice, Inbred C57BL, Mice, Knockout, Neuropsychological Tests, Odorants, Receptors, Prostaglandin E, Receptors, Prostaglandin E, EP2 Subtype, Sensory Gating, Social Behavior, Spatial BehaviorAdded December 21, 2013
30 MeSH Terms