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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 14 of 14

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Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality.
Xu H, Aldrich MC, Chen Q, Liu H, Peterson NB, Dai Q, Levy M, Shah A, Han X, Ruan X, Jiang M, Li Y, Julien JS, Warner J, Friedman C, Roden DM, Denny JC
(2015) J Am Med Inform Assoc 22: 179-91
MeSH Terms: Administration, Oral, Adult, Diabetes Mellitus, Type 2, Drug Repositioning, Electronic Health Records, Humans, Hypoglycemic Agents, Information Storage and Retrieval, Metformin, Natural Language Processing, Neoplasms, Registries, Survival Analysis
Added May 6, 2016
0 Communities
3 Members
0 Resources
13 MeSH Terms
Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis.
Li B, Flaveny CA, Giambelli C, Fei DL, Han L, Hang BI, Bai F, Pei XH, Nose V, Burlingame O, Capobianco AJ, Orton D, Lee E, Robbins DJ
(2014) PLoS One 9: e101969
MeSH Terms: Adenomatous Polyposis Coli, Animals, Antineoplastic Agents, Cell Survival, Drug Approval, Drug Repositioning, Drug Screening Assays, Antitumor, HCT116 Cells, Humans, Mice, Inbred C57BL, Mice, Transgenic, Pyrvinium Compounds, Wnt Signaling Pathway
Added November 2, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Network-assisted prediction of potential drugs for addiction.
Sun J, Huang LC, Xu H, Zhao Z
(2014) Biomed Res Int 2014: 258784
MeSH Terms: Cluster Analysis, Databases, Factual, Drug Interactions, Drug Repositioning, Forecasting, Humans, Illicit Drugs, National Institute on Drug Abuse (U.S.), Substance-Related Disorders, United States
Added May 27, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Genetics of rheumatoid arthritis contributes to biology and drug discovery.
Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, Jiang L, Yin J, Ye L, Su DF, Yang J, Xie G, Keystone E, Westra HJ, Esko T, Metspalu A, Zhou X, Gupta N, Mirel D, Stahl EA, Diogo D, Cui J, Liao K, Guo MH, Myouzen K, Kawaguchi T, Coenen MJ, van Riel PL, van de Laar MA, Guchelaar HJ, Huizinga TW, Dieudé P, Mariette X, Bridges SL, Zhernakova A, Toes RE, Tak PP, Miceli-Richard C, Bang SY, Lee HS, Martin J, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Rantapää-Dahlqvist S, Arlestig L, Choi HK, Kamatani Y, Galan P, Lathrop M, RACI consortium, GARNET consortium, Eyre S, Bowes J, Barton A, de Vries N, Moreland LW, Criswell LA, Karlson EW, Taniguchi A, Yamada R, Kubo M, Liu JS, Bae SC, Worthington J, Padyukov L, Klareskog L, Gregersen PK, Raychaudhuri S, Stranger BE, De Jager PL, Franke L, Visscher PM, Brown MA, Yamanaka H, Mimori T, Takahashi A, Xu H, Behrens TW, Siminovitch KA, Momohara S, Matsuda F, Yamamoto K, Plenge RM
(2014) Nature 506: 376-81
MeSH Terms: Alleles, Animals, Arthritis, Rheumatoid, Asian Continental Ancestry Group, Case-Control Studies, Computational Biology, Drug Discovery, Drug Repositioning, European Continental Ancestry Group, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Hematologic Neoplasms, Humans, Male, Mice, Mice, Knockout, Molecular Targeted Therapy, Polymorphism, Single Nucleotide
Added May 27, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms