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Results: 11 to 20 of 20

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Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression.
Nedelcheva V, Gut I, Soucek P, Tichavská B, Týnkova L, Mráz J, Guengerich FP, Ingelman-Sundberg M
(1999) Arch Toxicol 73: 33-40
MeSH Terms: Benzene, Carbon Radioisotopes, Chelating Agents, Cytochrome P-450 CYP2E1, Ditiocarb, Genotype, Glutathione, Humans, Immunoblotting, Kinetics, Methane, Microsomes, Liver, Oxidation-Reduction, Solubility, Substrate Specificity, Water
Added May 26, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Characterization of a valine-lysine thiourea cross-link on rat globin produced by carbon disulfide or N,N-diethyldithiocarbamate in vivo.
Erve JC, Amarnath V, Sills RC, Morgan DL, Valentine WM
(1998) Chem Res Toxicol 11: 1128-36
MeSH Terms: Animals, Carbon Disulfide, Ditiocarb, Globins, Humans, Lysine, Male, Mass Spectrometry, Rats, Rats, Inbred F344, Rats, Sprague-Dawley, Thiourea, Valine
Added May 27, 2014
0 Communities
1 Members
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13 MeSH Terms
Carbon disulfide and N,N-diethyldithiocarbamate generate thiourea cross-links on erythrocyte spectrin in vivo.
Erve JC, Amarnath V, Graham DG, Sills RC, Morgan AL, Valentine WM
(1998) Chem Res Toxicol 11: 544-9
MeSH Terms: Animals, Carbon Disulfide, Chromatography, Gel, Cross-Linking Reagents, Ditiocarb, Erythrocytes, Hydrolysis, Indicators and Reagents, Male, Mass Spectrometry, Rats, Rats, Inbred F344, Serum Albumin, Bovine, Spectrin, Spectrophotometry, Ultraviolet
Added May 27, 2014
0 Communities
1 Members
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15 MeSH Terms
Release of carbon disulfide is a contributing mechanism in the axonopathy produced by N,N-diethyldithiocarbamate.
Johnson DJ, Graham DG, Amarnath V, Amarnath K, Valentine WM
(1998) Toxicol Appl Pharmacol 148: 288-96
MeSH Terms: Animals, Axons, Carbon Disulfide, Chelating Agents, Cross-Linking Reagents, Ditiocarb, Erythrocytes, Hemoglobins, Male, Neurofilament Proteins, Rats, Rats, Sprague-Dawley, Spectrin, Spinal Cord, Tibial Nerve
Added February 12, 2015
0 Communities
1 Members
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15 MeSH Terms
Vascular superoxide dismutase deficiency impairs endothelial vasodilator function through direct inactivation of nitric oxide and increased lipid peroxidation.
Lynch SM, Frei B, Morrow JD, Roberts LJ, Xu A, Jackson T, Reyna R, Klevay LM, Vita JA, Keaney JF
(1997) Arterioscler Thromb Vasc Biol 17: 2975-81
MeSH Terms: Acetylcholine, Animals, Aorta, Thoracic, Calcimycin, Calcium, Chelating Agents, Copper, Ditiocarb, Endothelium, Vascular, Ionophores, Lipid Peroxidation, Male, Nitric Oxide, Oxidative Stress, Rats, Rats, Sprague-Dawley, Superoxide Dismutase, Superoxides, Vasodilation
Added December 10, 2013
0 Communities
1 Members
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19 MeSH Terms
Dialkyldithiocarbamates inhibit tyrosine hydroxylase activity in PC12 cells and in fibroblasts that express tyrosine hydroxylase.
Montine TJ, Underhill TM, Valentine WM, Graham DG
(1995) Neurodegeneration 4: 283-90
MeSH Terms: Analysis of Variance, Animals, Biopterin, CHO Cells, Cells, Cultured, Cricetinae, Dimethyldithiocarbamate, Ditiocarb, Enzyme Inhibitors, Fibroblasts, PC12 Cells, Rats, Thiocarbamates, Tyrosine 3-Monooxygenase
Added February 12, 2015
0 Communities
1 Members
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14 MeSH Terms
Carbon disulfide mediated protein cross-linking by N,N-diethyldithiocarbamate.
Valentine WM, Amarnath V, Amarnath K, Rimmele F, Graham DG
(1995) Chem Res Toxicol 8: 96-102
MeSH Terms: Animals, Carbon Disulfide, Cross-Linking Reagents, Ditiocarb, Gas Chromatography-Mass Spectrometry, Magnetic Resonance Spectroscopy, Proteins, Serum Albumin, Bovine, Swine, Thiourea
Added February 12, 2015
0 Communities
1 Members
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10 MeSH Terms
Morphological, neurochemical, and behavioral characterizations associated with the combined treatment of diethyldithiocarbamate and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
Yurek DM, Deutch AY, Roth RH, Sladek JR
(1989) Brain Res 497: 250-9
MeSH Terms: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, 3,4-Dihydroxyphenylacetic Acid, Animals, Apomorphine, Brain, Circadian Rhythm, Ditiocarb, Dopamine, Dose-Response Relationship, Drug, Drug Interactions, Immunoenzyme Techniques, Male, Mice, Mice, Inbred C57BL, Motor Activity, Reference Values, Stereotyped Behavior, Tyrosine 3-Monooxygenase
Added May 27, 2014
0 Communities
1 Members
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18 MeSH Terms
Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutase activity.
Mügge A, Elwell JH, Peterson TE, Harrison DG
(1991) Am J Physiol 260: C219-25
MeSH Terms: Acetylcholine, Amitrole, Animals, Bradykinin, Buthionine Sulfoximine, Calcimycin, Catalase, Cells, Cultured, Coronary Vessels, Ditiocarb, Endothelium, Vascular, Female, Glutathione, In Vitro Techniques, Male, Methionine Sulfoximine, Muscle, Smooth, Vascular, Nitric Oxide, Nitroprusside, Rabbits, Superoxide Dismutase, Swine, Vasodilation
Added December 10, 2013
1 Communities
1 Members
0 Resources
23 MeSH Terms
Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects.
Guengerich FP, Kim DH, Iwasaki M
(1991) Chem Res Toxicol 4: 168-79
MeSH Terms: Acrylonitrile, Animals, Antibodies, Benzene, Carcinogens, Cytochrome P-450 CYP2E1, Cytochrome P-450 Enzyme Inhibitors, Cytochrome P-450 Enzyme System, Ditiocarb, Humans, Hydrocarbons, Chlorinated, Kinetics, Microsomes, Liver, Molecular Weight, Oxidation-Reduction, Oxidoreductases, N-Demethylating, Rats, Styrene, Styrenes, Urethane, Vinyl Compounds
Added March 5, 2014
0 Communities
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21 MeSH Terms