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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 1415

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Hypusination Orchestrates the Antimicrobial Response of Macrophages.
Gobert AP, Finley JL, Latour YL, Asim M, Smith TM, Verriere TG, Barry DP, Allaman MM, Delagado AG, Rose KL, Calcutt MW, Schey KL, Sierra JC, Piazuelo MB, Mirmira RG, Wilson KT
(2020) Cell Rep 33: 108510
MeSH Terms: Animals, Anti-Infective Agents, Disease Models, Animal, Humans, Lysine, Macrophages, Mice
Added December 19, 2020
0 Communities
1 Members
0 Resources
7 MeSH Terms
RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT.
Kryshtal DO, Blackwell DJ, Egly CL, Smith AN, Batiste SM, Johnston JN, Laver DR, Knollmann BC
(2021) Circ Res 128: 321-331
MeSH Terms: Action Potentials, Animals, Anti-Arrhythmia Agents, Calcium Channel Blockers, Calcium Signaling, Calsequestrin, Disease Models, Animal, Female, Flecainide, HEK293 Cells, Heart Rate, Humans, Male, Mice, Knockout, Myocytes, Cardiac, Phosphorylation, Ryanodine Receptor Calcium Release Channel, Sarcoplasmic Reticulum, Sheep, Domestic, Tachycardia, Ventricular, Voltage-Gated Sodium Channel Blockers
Added December 21, 2020
1 Communities
0 Members
0 Resources
21 MeSH Terms
A Genetic Mouse Model Recapitulates Immune Checkpoint Inhibitor-Associated Myocarditis and Supports a Mechanism-Based Therapeutic Intervention.
Wei SC, Meijers WC, Axelrod ML, Anang NAS, Screever EM, Wescott EC, Johnson DB, Whitley E, Lehmann L, Courand PY, Mancuso JJ, Himmel LE, Lebrun-Vignes B, Wleklinski MJ, Knollmann BC, Srinivasan J, Li Y, Atolagbe OT, Rao X, Zhao Y, Wang J, Ehrlich LIR, Sharma P, Salem JE, Balko JM, Moslehi JJ, Allison JP
(2021) Cancer Discov 11: 614-625
MeSH Terms: Animals, Biomarkers, Tumor, Cardiotoxicity, Disease Management, Disease Models, Animal, Disease Susceptibility, Electrocardiography, Humans, Immune Checkpoint Inhibitors, Mice, Molecular Targeted Therapy, Myocarditis, Neoplasms
Added January 23, 2021
0 Communities
1 Members
0 Resources
13 MeSH Terms
Dicarbonyl Electrophiles Mediate Inflammation-Induced Gastrointestinal Carcinogenesis.
Gobert AP, Boutaud O, Asim M, Zagol-Ikapitte IA, Delgado AG, Latour YL, Finley JL, Singh K, Verriere TG, Allaman MM, Barry DP, McNamara KM, Sierra JC, Amarnath V, Tantawy MN, Bimczok D, Piazuelo MB, Washington MK, Zhao S, Coburn LA, Wilson KT
(2021) Gastroenterology 160: 1256-1268.e9
MeSH Terms: Animals, Benzylamines, Cell Nucleus, Cell Transformation, Neoplastic, Colitis-Associated Neoplasms, Disease Models, Animal, Epithelial Cells, Gastric Mucosa, Gastritis, Gerbillinae, Helicobacter Infections, Helicobacter pylori, Humans, Lipids, Metaplasia, Mice, Mice, Transgenic, Organoids, Precancerous Conditions, Stomach Neoplasms
Added March 17, 2021
0 Communities
1 Members
0 Resources
20 MeSH Terms
Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer.
Hoover AA, Hufnagel DH, Harris W, Bullock K, Glass EB, Liu E, Barham W, Crispens MA, Khabele D, Giorgio TD, Wilson AJ, Yull FE
(2020) BMC Cancer 20: 970
MeSH Terms: Animals, Cell Line, Tumor, Disease Models, Animal, Disease Progression, Female, Humans, Macrophages, Mice, Mice, Transgenic, NF-kappa B, Signal Transduction
Added January 29, 2021
1 Communities
0 Members
0 Resources
11 MeSH Terms
A smooth muscle-derived, Braf-driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell-of-origin.
Kondo J, Huh WJ, Franklin JL, Heinrich MC, Rubin BP, Coffey RJ
(2020) J Pathol 252: 441-450
MeSH Terms: Animals, Biomarkers, Tumor, Disease Models, Animal, Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors, Mice, Muscle, Smooth, Mutation, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins c-kit, Receptor, Platelet-Derived Growth Factor alpha
Added September 25, 2020
1 Communities
0 Members
0 Resources
11 MeSH Terms
Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation.
Banerjee A, Herring CA, Chen B, Kim H, Simmons AJ, Southard-Smith AN, Allaman MM, White JR, Macedonia MC, Mckinley ET, Ramirez-Solano MA, Scoville EA, Liu Q, Wilson KT, Coffey RJ, Washington MK, Goettel JA, Lau KS
(2020) Gastroenterology 159: 2101-2115.e5
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Chemoreceptor Cells, Crohn Disease, DNA, Bacterial, Disease Models, Animal, Feces, Female, Gastrointestinal Microbiome, Humans, Ileitis, Ileum, Intestinal Mucosa, Male, Mice, Mice, Knockout, Protective Factors, RNA, Ribosomal, 16S, RNA-Seq, Single-Cell Analysis, Succinic Acid
Added September 17, 2020
0 Communities
1 Members
0 Resources
21 MeSH Terms
Selective inhibition of mTORC1 in tumor vessels increases antitumor immunity.
Wang S, Raybuck A, Shiuan E, Cho SH, Wang Q, Brantley-Sieders DM, Edwards D, Allaman MM, Nathan J, Wilson KT, DeNardo D, Zhang S, Cook R, Boothby M, Chen J
(2020) JCI Insight 5:
MeSH Terms: Animals, Antineoplastic Agents, Breast Neoplasms, Carcinoma, Lewis Lung, Disease Models, Animal, Endothelium, Vascular, Everolimus, Female, Humans, Lymphocytes, Tumor-Infiltrating, Mechanistic Target of Rapamycin Complex 1, Mice, Mice, Inbred C57BL, Signal Transduction
Added September 17, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease.
Brubaker DK, Kumar MP, Chiswick EL, Gregg C, Starchenko A, Vega PN, Southard-Smith AN, Simmons AJ, Scoville EA, Coburn LA, Wilson KT, Lau KS, Lauffenburger DA
(2020) Sci Signal 13:
MeSH Terms: Animals, Cells, Cultured, Disease Models, Animal, Drug Resistance, Gastrointestinal Agents, Gene Expression Profiling, Humans, Inflammatory Bowel Diseases, Infliximab, Integrin alpha1, Integrins, Male, Mice, Proteomics, RNA-Seq, Signal Transduction, Single-Cell Analysis, Species Specificity, Translational Research, Biomedical
Added August 6, 2020
0 Communities
1 Members
0 Resources
19 MeSH Terms
Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D.
DelGiorno KE, Chung CY, Vavinskaya V, Maurer HC, Novak SW, Lytle NK, Ma Z, Giraddi RR, Wang D, Fang L, Naeem RF, Andrade LR, Ali WH, Tseng H, Tsui C, Gubbala VB, Ridinger-Saison M, Ohmoto M, Erikson GA, O'Connor C, Shokhirev MN, Hah N, Urade Y, Matsumoto I, Kaech SM, Singh PK, Manor U, Olive KP, Wahl GM
(2020) Gastroenterology 159: 1866-1881.e8
MeSH Terms: Animals, Carcinoma, Pancreatic Ductal, Cell Transformation, Neoplastic, Ceruletide, Disease Models, Animal, Energy Metabolism, Fibrosis, Humans, Interleukins, Intramolecular Oxidoreductases, Mice, Transgenic, Mutation, Octamer Transcription Factors, Pancreas, Pancreatic Neoplasms, Pancreatitis, Prostaglandin D2, Proto-Oncogene Proteins p21(ras), Time Factors, Transcription Factors
Added March 13, 2021
0 Communities
1 Members
0 Resources
20 MeSH Terms