Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 11 to 20 of 22

Publication Record

Connections

Metal-ion dependence of the active-site conformation of the translesion DNA polymerase Dpo4 from Sulfolobus solfataricus.
Irimia A, Loukachevitch LV, Eoff RL, Guengerich FP, Egli M
(2010) Acta Crystallogr Sect F Struct Biol Cryst Commun 66: 1013-8
MeSH Terms: Biocatalysis, Calcium, Catalytic Domain, Cations, Divalent, Crystallography, X-Ray, DNA Polymerase beta, Magnesium, Models, Molecular, Protein Binding, Structural Homology, Protein, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
2 Members
0 Resources
11 MeSH Terms
Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).
Christov PP, Petrova KV, Shanmugam G, Kozekov ID, Kozekova A, Guengerich FP, Stone MP, Rizzo CJ
(2010) Chem Res Toxicol 23: 1330-41
MeSH Terms: Chromatography, High Pressure Liquid, DNA Polymerase beta, Deoxyadenosines, Guanine, Molecular Structure, Oligonucleotides, Spectrometry, Mass, Electrospray Ionization, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
3 Members
0 Resources
8 MeSH Terms
Effect of N2-guanyl modifications on early steps in catalysis of polymerization by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W.
Zhang H, Guengerich FP
(2010) J Mol Biol 395: 1007-18
MeSH Terms: Amino Acid Substitution, Archaeal Proteins, Base Sequence, Catalytic Domain, DNA Adducts, DNA Polymerase beta, DNA Replication, DNA, Archaeal, Deoxycytosine Nucleotides, Kinetics, Molecular Structure, Mutagenesis, Site-Directed, Nucleic Acid Conformation, Protein Conformation, Recombinant Proteins, Spectrometry, Fluorescence, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation.
Zhang H, Beckman JW, Guengerich FP
(2009) J Biol Chem 284: 35144-53
MeSH Terms: Archaeal Proteins, DNA Polymerase beta, DNA, Archaeal, Frameshift Mutation, Humans, Hydrogen Bonding, Molecular Structure, Nucleic Acid Conformation, Purines, Sulfolobus solfataricus
Added March 26, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases.
Zhang H, Bren U, Kozekov ID, Rizzo CJ, Stec DF, Guengerich FP
(2009) J Mol Biol 392: 251-69
MeSH Terms: Bacteriophage T7, Base Pair Mismatch, DNA, DNA Polymerase beta, DNA Replication, DNA-Directed DNA Polymerase, Deamination, Deoxyribonucleosides, Inosine, Kinetics, Static Electricity, Sulfolobus solfataricus
Added March 26, 2014
0 Communities
3 Members
0 Resources
12 MeSH Terms
Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts.
Zhang H, Eoff RL, Kozekov ID, Rizzo CJ, Egli M, Guengerich FP
(2009) J Biol Chem 284: 3563-76
MeSH Terms: Archaeal Proteins, DNA Adducts, DNA Polymerase beta, DNA Replication, DNA, Archaeal, Deoxycytosine Nucleotides, Kinetics, Protein Conformation, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
3 Members
0 Resources
9 MeSH Terms
Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV.
Wang Y, Musser SK, Saleh S, Marnett LJ, Egli M, Stone MP
(2008) Biochemistry 47: 7322-34
MeSH Terms: Animals, Archaeal Proteins, DNA, DNA Polymerase beta, Deoxyguanosine, Dideoxynucleotides, Humans, Malondialdehyde, Oligodeoxyribonucleotides, Rodentia, Substrate Specificity, Sulfolobus solfataricus
Added March 5, 2014
0 Communities
3 Members
0 Resources
12 MeSH Terms
Structure and activity of Y-class DNA polymerase DPO4 from Sulfolobus solfataricus with templates containing the hydrophobic thymine analog 2,4-difluorotoluene.
Irimia A, Eoff RL, Pallan PS, Guengerich FP, Egli M
(2007) J Biol Chem 282: 36421-33
MeSH Terms: Bacterial Proteins, Crystallography, X-Ray, DNA Polymerase beta, DNA, Bacterial, Hydrophobic and Hydrophilic Interactions, Kinetics, Nucleotides, Protein Structure, Tertiary, Structure-Activity Relationship, Sulfolobus solfataricus, Thymine, Toluene
Added March 5, 2014
0 Communities
2 Members
0 Resources
12 MeSH Terms
Hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4.
Eoff RL, Irimia A, Angel KC, Egli M, Guengerich FP
(2007) J Biol Chem 282: 19831-43
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Amino Acid Substitution, Archaeal Proteins, Crystallography, X-Ray, DNA Polymerase beta, DNA, Archaeal, Deoxyguanosine, Hydrogen Bonding, Mutation, Missense, Protein Structure, Tertiary, Sulfolobus solfataricus
Added March 5, 2014
0 Communities
2 Members
0 Resources
11 MeSH Terms
Molecular basis of selectivity of nucleoside triphosphate incorporation opposite O6-benzylguanine by sulfolobus solfataricus DNA polymerase Dpo4: steady-state and pre-steady-state kinetics and x-ray crystallography of correct and incorrect pairing.
Eoff RL, Angel KC, Egli M, Guengerich FP
(2007) J Biol Chem 282: 13573-84
MeSH Terms: Archaeal Proteins, Base Pair Mismatch, Base Pairing, Crystallography, X-Ray, DNA Polymerase beta, DNA Replication, DNA, Archaeal, DNA-Directed DNA Polymerase, Deoxyribonucleotides, Guanine, HIV Reverse Transcriptase, Humans, Kinetics, Mass Spectrometry, Sulfolobus solfataricus
Added March 5, 2014
0 Communities
2 Members
0 Resources
15 MeSH Terms