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Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas.
Gao SP, Mark KG, Leslie K, Pao W, Motoi N, Gerald WL, Travis WD, Bornmann W, Veach D, Clarkson B, Bromberg JF
(2007) J Clin Invest 117: 3846-56
MeSH Terms: Adenocarcinoma, Animals, Cell Line, Tumor, Cytokine Receptor gp130, Enzyme Inhibitors, ErbB Receptors, Female, Gene Expression Regulation, Neoplastic, Humans, Interleukin-6, Janus Kinases, Lung Neoplasms, Mice, Mice, Nude, Mutation, Neoplasm Transplantation, Phosphorylation, RNA, Small Interfering, STAT3 Transcription Factor, Signal Transduction, Transcription, Genetic
Added March 24, 2014
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21 MeSH Terms