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Results: 11 to 20 of 42

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Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1B1 in inhibiting catalytic activity.
Shimada T, Murajama N, Tanaka K, Takenaka S, Imai Y, Hopkins NE, Foroozesh MK, Alworth WL, Yamazaki H, Guengerich FP, Komori M
(2008) Chem Res Toxicol 21: 2313-23
MeSH Terms: Aryl Hydrocarbon Hydroxylases, Computer Simulation, Cytochrome P-450 CYP1A1, Cytochrome P-450 CYP1B1, Enzyme Inhibitors, Humans, Models, Molecular, Polycyclic Aromatic Hydrocarbons, Protein Conformation
Added March 26, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
CYP1A1/2 haplotypes and lung cancer and assessment of confounding by population stratification.
Aldrich MC, Selvin S, Hansen HM, Barcellos LF, Wrensch MR, Sison JD, Kelsey KT, Buffler PA, Quesenberry CP, Seldin MF, Wiencke JK
(2009) Cancer Res 69: 2340-8
MeSH Terms: African Americans, Aged, Aged, 80 and over, California, Case-Control Studies, Confounding Factors, Epidemiologic, Cytochrome P-450 CYP1A1, Cytochrome P-450 CYP1A2, Female, Haplotypes, Hispanic or Latino, Humans, Linkage Disequilibrium, Lung Neoplasms, Male, Middle Aged, Polymorphism, Single Nucleotide
Added February 26, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Genetic polymorphisms in estrogen-metabolizing genes and breast cancer survival.
Long JR, Cai Q, Shu XO, Cai H, Gao YT, Zheng W
(2007) Pharmacogenet Genomics 17: 331-8
MeSH Terms: Adult, Aryl Hydrocarbon Hydroxylases, Breast Neoplasms, Catechol O-Methyltransferase, Cohort Studies, Cytochrome P-450 CYP1A1, Cytochrome P-450 CYP1A2, Cytochrome P-450 CYP1B1, Cytochrome P-450 Enzyme System, Estrogens, Female, Genotype, Humans, Middle Aged, Polymorphism, Single Nucleotide, Receptors, Aryl Hydrocarbon
Added December 10, 2013
0 Communities
2 Members
0 Resources
16 MeSH Terms
Different mechanisms for inhibition of human cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic inhibitors.
Shimada T, Murayama N, Okada K, Funae Y, Yamazaki H, Guengerich FP
(2007) Chem Res Toxicol 20: 489-96
MeSH Terms: Aryl Hydrocarbon Hydroxylases, Catalysis, Cytochrome P-450 CYP1A1, Cytochrome P-450 CYP1A2, Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP1B1, Enzyme Inhibitors, Humans, Kinetics, Oxazines, Polycyclic Aromatic Hydrocarbons
Added March 5, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Developmental exposure of mice to TCDD elicits a similar uterine phenotype in adult animals as observed in women with endometriosis.
Nayyar T, Bruner-Tran KL, Piestrzeniewicz-Ulanska D, Osteen KG
(2007) Reprod Toxicol 23: 326-36
MeSH Terms: Animals, Blotting, Western, Cytochrome P-450 CYP1A1, Disease Models, Animal, Endometriosis, Endometrium, Environmental Pollutants, Estradiol, Female, Humans, Immunohistochemistry, Liver, Male, Mice, Mice, Inbred C57BL, Organ Culture Techniques, Ovariectomy, Polychlorinated Dibenzodioxins, Pregnancy, Progesterone, Receptors, Progesterone, Sex Factors, Transforming Growth Factor beta2, Uterus
Added May 29, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
Estrogens, enzyme variants, and breast cancer: a risk model.
Crooke PS, Ritchie MD, Hachey DL, Dawling S, Roodi N, Parl FF
(2006) Cancer Epidemiol Biomarkers Prev 15: 1620-9
MeSH Terms: Area Under Curve, Aryl Hydrocarbon Hydroxylases, Breast Neoplasms, Catechol O-Methyltransferase, Cytochrome P-450 CYP1A1, Cytochrome P-450 CYP1B1, Estrogens, Female, Haplotypes, Humans, Models, Theoretical
Added March 20, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Inhibition of human cytochrome P450 1A1-, 1A2-, and 1B1-mediated activation of procarcinogens to genotoxic metabolites by polycyclic aromatic hydrocarbons.
Shimada T, Guengerich FP
(2006) Chem Res Toxicol 19: 288-94
MeSH Terms: Aryl Hydrocarbon Hydroxylases, Carcinogens, Cytochrome P-450 CYP1A1, Cytochrome P-450 CYP1A2, Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP1B1, Enzyme Activation, Enzyme Inhibitors, Humans, Molecular Structure, Polycyclic Aromatic Hydrocarbons, Salmonella typhimurium, Structure-Activity Relationship
Added March 5, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Polymorphisms in CYP1A1 and breast carcinoma risk in a population-based case-control study of Chinese women.
Boyapati SM, Shu XO, Gao YT, Cai Q, Jin F, Zheng W
(2005) Cancer 103: 2228-35
MeSH Terms: Breast Neoplasms, Case-Control Studies, China, Cytochrome P-450 CYP1A1, Estrogens, Female, Genotype, Homozygote, Humans, Menopause, Middle Aged, Polymorphism, Genetic, Risk Factors, Waist-Hip Ratio
Added December 10, 2013
0 Communities
2 Members
0 Resources
14 MeSH Terms
In vitro model of mammary estrogen metabolism: structural and kinetic differences between catechol estrogens 2- and 4-hydroxyestradiol.
Dawling S, Hachey DL, Roodi N, Parl FF
(2004) Chem Res Toxicol 17: 1258-64
MeSH Terms: Animals, Aryl Hydrocarbon Hydroxylases, Catechol O-Methyltransferase, Cytochrome P-450 CYP1A1, Cytochrome P-450 CYP1B1, Estradiol, Estrogens, Catechol, Glutathione S-Transferase pi, Glutathione Transferase, Humans, Isoenzymes, Kinetics, Mammary Glands, Animal, Mammary Glands, Human, Models, Chemical, Models, Molecular, Oxidation-Reduction, Recombinant Proteins, Structure-Activity Relationship
Added March 20, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Expression of cytochromes P450 1A1 and 1B1 in human lung from smokers, non-smokers, and ex-smokers.
Kim JH, Sherman ME, Curriero FC, Guengerich FP, Strickland PT, Sutter TR
(2004) Toxicol Appl Pharmacol 199: 210-9
MeSH Terms: Adolescent, Adult, Aged, Aged, 80 and over, Aryl Hydrocarbon Hydroxylases, Cytochrome P-450 CYP1A1, Cytochrome P-450 CYP1B1, Epithelial Cells, Female, Humans, Immunoblotting, Immunohistochemistry, Lung, Lung Neoplasms, Male, Microsomes, Middle Aged, Pulmonary Alveoli, Smoking
Added May 26, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms