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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 30

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Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses.
Agnihothram S, Gopal R, Yount BL, Donaldson EF, Menachery VD, Graham RL, Scobey TD, Gralinski LE, Denison MR, Zambon M, Baric RS
(2014) J Infect Dis 209: 995-1006
MeSH Terms: Animals, Antibodies, Viral, Antigens, Viral, Blotting, Western, Chiroptera, Coronaviridae, Coronavirus Nucleocapsid Proteins, Cross Reactions, Enzyme-Linked Immunosorbent Assay, Humans, Mice, Mice, Inbred BALB C, Middle Aged, Neutralization Tests, Nucleocapsid Proteins, Spike Glycoprotein, Coronavirus
Added February 19, 2015
0 Communities
1 Members
0 Resources
16 MeSH Terms
Chimeric exchange of coronavirus nsp5 proteases (3CLpro) identifies common and divergent regulatory determinants of protease activity.
Stobart CC, Sexton NR, Munjal H, Lu X, Molland KL, Tomar S, Mesecar AD, Denison MR
(2013) J Virol 87: 12611-8
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Animals, Chimera, Conserved Sequence, Coronavirus, Coronavirus Infections, Cricetinae, Evolution, Molecular, Humans, Mice, Molecular Sequence Data, Peptide Hydrolases, Phylogeny, Protein Structure, Tertiary, Sequence Alignment, Viral Proteins
Added February 19, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics.
Smith EC, Blanc H, Surdel MC, Vignuzzi M, Denison MR
(2013) PLoS Pathog 9: e1003565
MeSH Terms: Animals, Antiviral Agents, Apoptosis, Astrocytoma, Brain Neoplasms, Cell Proliferation, Coronavirus, Coronavirus Infections, Exoribonucleases, Genome, Viral, Humans, Mice, Mutagenesis, Mutagens, Mutation, RNA, Messenger, RNA, Viral, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Tumor Cells, Cultured, Viral Proteins, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
22 MeSH Terms
Implications of altered replication fidelity on the evolution and pathogenesis of coronaviruses.
Smith EC, Denison MR
(2012) Curr Opin Virol 2: 519-24
MeSH Terms: Animals, Coronavirus, Coronavirus Infections, Evolution, Molecular, Genome, Viral, Humans, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
7 MeSH Terms
Temperature-sensitive mutants and revertants in the coronavirus nonstructural protein 5 protease (3CLpro) define residues involved in long-distance communication and regulation of protease activity.
Stobart CC, Lee AS, Lu X, Denison MR
(2012) J Virol 86: 4801-10
MeSH Terms: Alleles, Amino Acid Sequence, Amino Acid Substitution, Animals, Coronavirus 3C Proteases, Cricetinae, Cysteine Endopeptidases, Enzyme Activation, Gene Order, Mice, Models, Molecular, Molecular Sequence Data, Murine hepatitis virus, Mutation, Phenotype, Protein Structure, Tertiary, Sequence Alignment, Temperature, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity.
Denison MR, Graham RL, Donaldson EF, Eckerle LD, Baric RS
(2011) RNA Biol 8: 270-9
MeSH Terms: Animals, Coronavirus, Evolution, Molecular, Genome, Viral, Humans, Mutation, RNA, Viral, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
8 MeSH Terms
The pediatric burden of human coronaviruses evaluated for twenty years.
Talbot HK, Shepherd BE, Crowe JE, Griffin MR, Edwards KM, Podsiad AB, Tollefson SJ, Wright PF, Williams JV
(2009) Pediatr Infect Dis J 28: 682-7
MeSH Terms: Child, Preschool, Coronavirus, Coronavirus Infections, Female, Humans, Incidence, Infant, Logistic Models, Male, Prospective Studies, Respiratory System, Respiratory Tract Infections, Reverse Transcriptase Polymerase Chain Reaction
Added August 6, 2012
0 Communities
1 Members
0 Resources
13 MeSH Terms
Coronavirus infection and hospitalizations for acute respiratory illness in young children.
Talbot HK, Crowe JE, Edwards KM, Griffin MR, Zhu Y, Weinberg GA, Szilagyi PG, Hall CB, Podsiad AB, Iwane M, Williams JV, New Vaccine Surveillance Network
(2009) J Med Virol 81: 853-6
MeSH Terms: Acute Disease, Child, Preschool, Coronavirus, Coronavirus 229E, Human, Coronavirus Infections, Coronavirus OC43, Human, Female, Hospitalization, Humans, Incidence, Infant, Infant, Newborn, Male, Population Surveillance, Respiratory System, Respiratory Tract Infections
Added August 6, 2012
0 Communities
1 Members
0 Resources
16 MeSH Terms
Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice.
Becker MM, Graham RL, Donaldson EF, Rockx B, Sims AC, Sheahan T, Pickles RJ, Corti D, Johnston RE, Baric RS, Denison MR
(2008) Proc Natl Acad Sci U S A 105: 19944-9
MeSH Terms: Amino Acid Sequence, Animals, Cells, Cultured, Chiroptera, Chlorocebus aethiops, Female, Humans, Membrane Glycoproteins, Mice, Mice, Inbred BALB C, Molecular Sequence Data, Recombinant Proteins, Recombination, Genetic, Respiratory Mucosa, SARS Virus, Severe Acute Respiratory Syndrome, Spike Glycoprotein, Coronavirus, Vero Cells, Viral Envelope Proteins, Virus Replication, Zoonoses
Added February 19, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Coronavirus replication does not require the autophagy gene ATG5.
Zhao Z, Thackray LB, Miller BC, Lynn TM, Becker MM, Ward E, Mizushima NN, Denison MR, Virgin HW
(2007) Autophagy 3: 581-5
MeSH Terms: Animals, Autophagy, Autophagy-Related Protein 5, Bone Marrow Cells, Cells, Cultured, Coronavirus, Coronavirus Infections, Embryo, Mammalian, Fibroblasts, Gene Deletion, Macrophages, Mice, Mice, Knockout, Mice, Transgenic, Microtubule-Associated Proteins, Murine hepatitis virus, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms