HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability.
Krishnan M, Singh AB, Smith JJ, Sharma A, Chen X, Eschrich S, Yeatman TJ, Beauchamp RD, Dhawan P
(2010) Oncogene 29
: 305-12MeSH Terms: 3' Untranslated Regions, Butyrates, Cell Line, Tumor, Cell Movement, Claudin-1, Colonic Neoplasms, Gene Expression Regulation, Neoplastic, Histone Deacetylase 2, Histone Deacetylase Inhibitors, Humans, Hydroxamic Acids, Immunoblotting, Membrane Proteins, RNA Interference, RNA Stability, RNA, Messenger, Reverse Transcriptase Polymerase Chain Reaction, Transcription, GeneticAdded June 14, 2013
18 MeSH Terms
Smad7 induces hepatic metastasis in colorectal cancer.
Halder SK, Rachakonda G, Deane NG, Datta PK
(2008) Br J Cancer 99
: 957-65MeSH Terms: Adenocarcinoma, Animals, Biomarkers, Tumor, Blotting, Western, Cadherins, Cell Proliferation, Claudin-1, Claudin-4, Colorectal Neoplasms, Gene Expression Regulation, Neoplastic, Humans, Liver Neoplasms, Membrane Proteins, Mice, Mice, Nude, Phosphorylation, Polymerase Chain Reaction, Protein-Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, Smad2 Protein, Smad3 Protein, Smad7 Protein, Transforming Growth Factor beta, Tumor Cells, CulturedAdded May 10, 2013
26 MeSH Terms
Regulation of metastasis in colorectal adenocarcinoma: a collision between development and tumor biology.
Smith JJ, Deane NG, Dhawan P, Beauchamp RD
(2008) Surgery 144
: 353-66MeSH Terms: Adenocarcinoma, Bone Morphogenetic Proteins, Cadherins, Claudin-1, Colorectal Neoplasms, Epigenesis, Genetic, Humans, Intercellular Junctions, Membrane Proteins, Neoplasm Metastasis, Neoplastic Processes, Signal Transduction, Transforming Growth Factor beta, Wnt ProteinsAdded June 14, 2013
14 MeSH Terms
Smad4 regulates claudin-1 expression in a transforming growth factor-beta-independent manner in colon cancer cells.
Shiou SR, Singh AB, Moorthy K, Datta PK, Washington MK, Beauchamp RD, Dhawan P
(2007) Cancer Res 67
: 1571-9MeSH Terms: Animals, Cell Line, Tumor, Claudin-1, Colorectal Neoplasms, HCT116 Cells, HT29 Cells, Humans, Membrane Proteins, Neoplasm Invasiveness, RNA, Messenger, Rats, Signal Transduction, Smad4 Protein, TCF Transcription Factors, Transcription, Genetic, Transfection, Transforming Growth Factor beta, beta CateninAdded June 14, 2013
18 MeSH Terms
Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer.
Dhawan P, Singh AB, Deane NG, No Y, Shiou SR, Schmidt C, Neff J, Washington MK, Beauchamp RD
(2005) J Clin Invest 115
: 1765-76MeSH Terms: Animals, Cell Line, Tumor, Cell Transformation, Neoplastic, Claudin-1, Colonic Neoplasms, Cytoskeletal Proteins, Female, Humans, Membrane Proteins, Mice, Mice, Nude, Neoplasm Metastasis, Neoplasm Transplantation, RNA, Small Interfering, Signal Transduction, Trans-Activators, Transplantation, Heterologous, beta CateninAdded June 14, 2013
18 MeSH Terms
Epidermal growth factor receptor activation differentially regulates claudin expression and enhances transepithelial resistance in Madin-Darby canine kidney cells.
Singh AB, Harris RC
(2004) J Biol Chem 279
: 3543-52MeSH Terms: Acetylcysteine, Adherens Junctions, Animals, Blotting, Northern, Bromodeoxyuridine, Cell Adhesion, Cell Differentiation, Cell Division, Cell Line, Claudin-1, Claudin-3, Claudin-4, Claudins, Cycloheximide, Detergents, Dogs, Epithelium, ErbB Receptors, Gene Expression Regulation, Hepatocyte Growth Factor, Immunoblotting, Kidney, Membrane Proteins, Microscopy, Fluorescence, Neoplasms, Octoxynol, Phenotype, Protein Synthesis Inhibitors, Signal Transduction, Tight Junctions, Time FactorsAdded August 19, 2013
31 MeSH Terms