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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 31

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Mutation of serine 1333 in the ATR HEAT repeats creates a hyperactive kinase.
Luzwick JW, Nam EA, Zhao R, Cortez D
(2014) PLoS One 9: e99397
MeSH Terms: Amino Acid Sequence, Amino Acid Substitution, Ataxia Telangiectasia Mutated Proteins, Carrier Proteins, Checkpoint Kinase 1, DNA Replication, DNA-Binding Proteins, G2 Phase Cell Cycle Checkpoints, HCT116 Cells, HEK293 Cells, Humans, Hydroxyurea, Molecular Sequence Data, Nuclear Proteins, Phosphorylation, Protein Binding, Protein Kinases, Protein Structure, Secondary, Radiation, Ionizing, Serine, Signal Transduction, Ultraviolet Rays
Added January 20, 2015
0 Communities
1 Members
0 Resources
22 MeSH Terms
The Mdm network and its regulation of p53 activities: a rheostat of cancer risk.
Eischen CM, Lozano G
(2014) Hum Mutat 35: 728-37
MeSH Terms: Animals, Cell Cycle Checkpoints, Cell Cycle Proteins, Cell Death, Cell Proliferation, Humans, Mice, Neoplasms, Nuclear Proteins, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-mdm2, Risk Factors, Transcription, Genetic, Tumor Suppressor Protein p53
Added March 5, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Direct monitoring of the strand passage reaction of DNA topoisomerase II triggers checkpoint activation.
Furniss KL, Tsai HJ, Byl JA, Lane AB, Vas AC, Hsu WS, Osheroff N, Clarke DJ
(2013) PLoS Genet 9: e1003832
MeSH Terms: Cell Cycle, Cell Cycle Checkpoints, Cell Cycle Proteins, Checkpoint Kinase 2, Chromosome Segregation, DNA, DNA Topoisomerases, Type II, Humans, Kinetochores, Mad2 Proteins, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins
Added March 7, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Nonstructural protein σ1s mediates reovirus-induced cell cycle arrest and apoptosis.
Boehme KW, Hammer K, Tollefson WC, Konopka-Anstadt JL, Kobayashi T, Dermody TS
(2013) J Virol 87: 12967-79
MeSH Terms: Amino Acid Motifs, Animals, Apoptosis, Cell Cycle Checkpoints, Cell Line, Humans, Mammalian orthoreovirus 3, Mice, Reoviridae Infections, Viral Nonstructural Proteins, Virus Replication
Added May 20, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
CK1 is required for a mitotic checkpoint that delays cytokinesis.
Johnson AE, Chen JS, Gould KL
(2013) Curr Biol 23: 1920-6
MeSH Terms: Casein Kinase I, Cell Cycle Proteins, Cell Division, Cytokinesis, Green Fluorescent Proteins, M Phase Cell Cycle Checkpoints, Microtubule-Associated Proteins, Nuclear Proteins, Phosphorylation, Protein Kinases, Protein Serine-Threonine Kinases, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Signal Transduction, Spindle Pole Bodies, Ubiquitination
Added March 7, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer.
Peng Y, Dai Y, Hitchcock C, Yang X, Kassis ES, Liu L, Luo Z, Sun HL, Cui R, Wei H, Kim T, Lee TJ, Jeon YJ, Nuovo GJ, Volinia S, He Q, Yu J, Nana-Sinkam P, Croce CM
(2013) Proc Natl Acad Sci U S A 110: 15043-8
MeSH Terms: 3' Untranslated Regions, Animals, Apoptosis, Carcinoma, Non-Small-Cell Lung, Cell Cycle Checkpoints, Cell Line, Tumor, Cell Movement, Cell Proliferation, Class Ia Phosphatidylinositol 3-Kinase, Gene Expression Regulation, Neoplastic, Genes, Tumor Suppressor, Genes, p53, Humans, Insulin-Like Growth Factor I, Lung Neoplasms, Mice, Mice, Nude, MicroRNAs, Phosphoinositide-3 Kinase Inhibitors, RNA, Small Interfering, Receptor, IGF Type 1, Signal Transduction
Added December 22, 2013
0 Communities
1 Members
0 Resources
22 MeSH Terms
Mechanisms of reovirus bloodstream dissemination.
Boehme KW, Lai CM, Dermody TS
(2013) Adv Virus Res 87: 1-35
MeSH Terms: Animals, Apoptosis, Capsid Proteins, Cell Adhesion Molecules, Cell Cycle Checkpoints, Humans, Intestinal Mucosa, Intestines, Lung, Mice, Receptors, Cell Surface, Receptors, Virus, Reoviridae, Reoviridae Infections, Respiratory Mucosa, Viremia, Virus Replication
Added December 10, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Impaired liver regeneration in Ldlr-/- mice is associated with an altered hepatic profile of cytokines, growth factors, and lipids.
Pauta M, Rotllan N, Vales F, Fernandez-Hernando A, Allen RM, Ford DA, Marí M, Jiménez W, Baldán A, Morales-Ruiz M, Fernández-Hernando C
(2013) J Hepatol 59: 731-7
MeSH Terms: Animals, Cell Cycle Checkpoints, Cholesterol, Fatty Liver, Hepatectomy, Hepatocyte Growth Factor, Hypercholesterolemia, Interleukin-6, Lipid Metabolism, Liver, Liver Regeneration, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Receptors, LDL, Signal Transduction, Tumor Necrosis Factor-alpha
Added February 12, 2016
0 Communities
1 Members
0 Resources
18 MeSH Terms
Berberine inhibits proliferation and down-regulates epidermal growth factor receptor through activation of Cbl in colon tumor cells.
Wang L, Cao H, Lu N, Liu L, Wang B, Hu T, Israel DA, Peek RM, Polk DB, Yan F
(2013) PLoS One 8: e56666
MeSH Terms: Animals, Antineoplastic Agents, Berberine, Cell Cycle Checkpoints, Cell Proliferation, Colonic Neoplasms, Down-Regulation, Enzyme Activation, ErbB Receptors, HT29 Cells, Humans, Mice, Mice, Inbred C57BL, Proto-Oncogene Proteins c-cbl, Xenograft Model Antitumor Assays
Added September 3, 2013
0 Communities
4 Members
0 Resources
15 MeSH Terms
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury.
Kashani K, Al-Khafaji A, Ardiles T, Artigas A, Bagshaw SM, Bell M, Bihorac A, Birkhahn R, Cely CM, Chawla LS, Davison DL, Feldkamp T, Forni LG, Gong MN, Gunnerson KJ, Haase M, Hackett J, Honore PM, Hoste EA, Joannes-Boyau O, Joannidis M, Kim P, Koyner JL, Laskowitz DT, Lissauer ME, Marx G, McCullough PA, Mullaney S, Ostermann M, Rimmelé T, Shapiro NI, Shaw AD, Shi J, Sprague AM, Vincent JL, Vinsonneau C, Wagner L, Walker MG, Wilkerson RG, Zacharowski K, Kellum JA
(2013) Crit Care 17: R25
MeSH Terms: Acute Kidney Injury, Aged, Biomarkers, Cell Cycle Checkpoints, Cohort Studies, Female, Humans, Insulin-Like Growth Factor Binding Proteins, Male, Middle Aged, Tissue Inhibitor of Metalloproteinase-2
Added October 20, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms