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Results: 11 to 20 of 48

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Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans.
Wheeler HE, Gorsic LK, Welsh M, Stark AL, Gamazon ER, Cox NJ, Dolan ME
(2011) PLoS One 6: e21920
MeSH Terms: African Americans, Antineoplastic Agents, Carboplatin, Cell Death, Cell Line, Child, Cisplatin, Drug Resistance, Neoplasm, Female, Genealogy and Heraldry, Genes, Genome, Human, Genome-Wide Association Study, Humans, Male, Phenotype, Polymorphism, Single Nucleotide, Southwestern United States
Added February 22, 2016
0 Communities
2 Members
0 Resources
18 MeSH Terms
Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients.
Huang RS, Johnatty SE, Gamazon ER, Im HK, Ziliak D, Duan S, Zhang W, Kistner EO, Chen P, Beesley J, Mi S, O'Donnell PH, Fraiman YS, Das S, Cox NJ, Lu Y, Macgregor S, Goode EL, Vierkant RA, Fridley BL, Hogdall E, Kjaer SK, Jensen A, Moysich KB, Grasela M, Odunsi K, Brown R, Paul J, Lambrechts D, Despierre E, Vergote I, Gross J, Karlan BY, Defazio A, Chenevix-Trench G, Australian Ovarian Cancer Study Group, Dolan ME
(2011) Clin Cancer Res 17: 5490-500
MeSH Terms: Antineoplastic Agents, Carboplatin, Cell Line, Cell Line, Tumor, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Genome, Human, Genome-Wide Association Study, Humans, Kaplan-Meier Estimate, Ovarian Neoplasms, Polymorphism, Single Nucleotide, Prognosis, Treatment Outcome
Added February 22, 2016
0 Communities
2 Members
0 Resources
15 MeSH Terms
A phase II study of carboplatin and irinotecan in extensive stage small-cell lung cancer.
Horn L, Zhao Z, Sandler A, Johnson D, Shyr Y, Wolff S, Devore RF, Laskin J
(2011) Clin Lung Cancer 12: 161-5
MeSH Terms: Antineoplastic Combined Chemotherapy Protocols, Camptothecin, Carboplatin, Female, Humans, Irinotecan, Lung Neoplasms, Male, Middle Aged, Neoplasm Staging, Small Cell Lung Carcinoma
Added February 13, 2014
0 Communities
2 Members
0 Resources
11 MeSH Terms
Copy number polymorphisms and anticancer pharmacogenomics.
Gamazon ER, Huang RS, Dolan ME, Cox NJ
(2011) Genome Biol 12: R46
MeSH Terms: Antineoplastic Agents, Biomarkers, Pharmacological, Carboplatin, Cell Line, Tumor, Cisplatin, Daunorubicin, Etoposide, Gene Dosage, Gene Expression, Genetic Predisposition to Disease, Genetic Variation, Genome, Human, Genome-Wide Association Study, Humans, Inhibitory Concentration 50, Neoplasms, Oligonucleotide Array Sequence Analysis, Pharmacogenetics, Phenotype, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Topoisomerase II Inhibitors
Added February 22, 2016
0 Communities
2 Members
0 Resources
22 MeSH Terms
Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers.
Ziliak D, O'Donnell PH, Im HK, Gamazon ER, Chen P, Delaney S, Shukla S, Das S, Cox NJ, Vokes EE, Cohen EE, Dolan ME, Huang RS
(2011) Transl Res 157: 265-72
MeSH Terms: Antineoplastic Agents, Biomarkers, Carboplatin, Cell Line, Genome-Wide Association Study, Head and Neck Neoplasms, Humans, Models, Biological, Platinum, Polymorphism, Genetic, Treatment Outcome
Added February 22, 2016
0 Communities
2 Members
0 Resources
11 MeSH Terms
Comprehensive evaluation of the contribution of X chromosome genes to platinum sensitivity.
Gamazon ER, Im HK, O'Donnell PH, Ziliak D, Stark AL, Cox NJ, Dolan ME, Huang RS
(2011) Mol Cancer Ther 10: 472-80
MeSH Terms: Carboplatin, Cell Line, Tumor, Chromosomes, Human, X, Cisplatin, Drug Resistance, Neoplasm, Gene Expression, Genes, X-Linked, Genome-Wide Association Study, Humans
Added February 22, 2016
0 Communities
2 Members
0 Resources
9 MeSH Terms
Population differences in platinum toxicity as a means to identify novel genetic susceptibility variants.
O'Donnell PH, Gamazon E, Zhang W, Stark AL, Kistner-Griffin EO, Stephanie Huang R, Eileen Dolan M
(2010) Pharmacogenet Genomics 20: 327-37
MeSH Terms: Asians, Blacks, Carboplatin, Cell Line, Transformed, Cisplatin, Genetic Predisposition to Disease, Genetic Variation, Genetics, Population, Genome-Wide Association Study, Humans, Inhibitory Concentration 50, Lymphocytes, Pharmacogenetics, Phenotype, Platinum, Whites
Added April 13, 2017
0 Communities
1 Members
0 Resources
16 MeSH Terms
Surgery with or without preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer: Southwest Oncology Group Trial S9900, an intergroup, randomized, phase III trial.
Pisters KM, Vallières E, Crowley JJ, Franklin WA, Bunn PA, Ginsberg RJ, Putnam JB, Chansky K, Gandara D
(2010) J Clin Oncol 28: 1843-9
MeSH Terms: Adenocarcinoma, Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols, Carboplatin, Carcinoma, Large Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Combined Modality Therapy, Female, Humans, Lung Neoplasms, Male, Middle Aged, Neoplasm Staging, Paclitaxel, Survival Rate, Thoracic Surgery, Treatment Outcome
Added March 27, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Hypothyroidism as a consequence of intensity-modulated radiotherapy with concurrent taxane-based chemotherapy for locally advanced head-and-neck cancer.
Diaz R, Jaboin JJ, Morales-Paliza M, Koehler E, Phillips JG, Stinson S, Gilbert J, Chung CH, Murphy BA, Yarbrough WG, Murphy PB, Shyr Y, Cmelak AJ
(2010) Int J Radiat Oncol Biol Phys 77: 468-76
MeSH Terms: Age Factors, Antineoplastic Combined Chemotherapy Protocols, Bridged-Ring Compounds, Carboplatin, Combined Modality Therapy, Dose Fractionation, Radiation, Female, Head and Neck Neoplasms, Humans, Hypothyroidism, Male, Middle Aged, Paclitaxel, Radiation Injuries, Radiography, Radiotherapy, Intensity-Modulated, Retrospective Studies, Risk Factors, Taxoids, Thyroid Gland
Added March 5, 2014
0 Communities
4 Members
0 Resources
20 MeSH Terms
A phase II study of celecoxib in combination with paclitaxel, carboplatin, and radiotherapy for patients with inoperable stage IIIA/B non-small cell lung cancer.
Mutter R, Lu B, Carbone DP, Csiki I, Moretti L, Johnson DH, Morrow JD, Sandler AB, Shyr Y, Ye F, Choy H
(2009) Clin Cancer Res 15: 2158-65
MeSH Terms: Aged, Antineoplastic Combined Chemotherapy Protocols, Carboplatin, Carcinoma, Non-Small-Cell Lung, Celecoxib, Combined Modality Therapy, Cyclooxygenase 2 Inhibitors, Female, Humans, Lung Neoplasms, Male, Middle Aged, Neoplasm Staging, Paclitaxel, Prostaglandins, Pyrazoles, Sulfonamides, Vascular Endothelial Growth Factor A
Added March 7, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms