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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 180

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CaMKII-mediated phosphorylation of GluN2B regulates recombinant NMDA receptor currents in a chloride-dependent manner.
Tavalin SJ, Colbran RJ
(2017) Mol Cell Neurosci 79: 45-52
MeSH Terms: Action Potentials, Calcium Signaling, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Chlorides, HEK293 Cells, Humans, Phosphorylation, Protein Binding, Protein Processing, Post-Translational, Receptors, N-Methyl-D-Aspartate
Added April 26, 2017
0 Communities
1 Members
0 Resources
10 MeSH Terms
Novel CPVT-Associated Calmodulin Mutation in CALM3 (CALM3-A103V) Activates Arrhythmogenic Ca Waves and Sparks.
Gomez-Hurtado N, Boczek NJ, Kryshtal DO, Johnson CN, Sun J, Nitu FR, Cornea RL, Chazin WJ, Calvert ML, Tester DJ, Ackerman MJ, Knollmann BC
(2016) Circ Arrhythm Electrophysiol 9:
MeSH Terms: Action Potentials, Adult, Animals, Calmodulin, DNA Mutational Analysis, Electrocardiography, Exercise Test, Female, Genotype, Humans, Long QT Syndrome, Male, Mice, Phenotype, Ryanodine, Tachycardia, Ventricular
Added April 18, 2017
0 Communities
1 Members
0 Resources
16 MeSH Terms
Novel calmodulin mutations associated with congenital long QT syndrome affect calcium current in human cardiomyocytes.
Pipilas DC, Johnson CN, Webster G, Schlaepfer J, Fellmann F, Sekarski N, Wren LM, Ogorodnik KV, Chazin DM, Chazin WJ, Crotti L, Bhuiyan ZA, George AL
(2016) Heart Rhythm 13: 2012-9
MeSH Terms: Action Potentials, Calmodulin, Child, Preschool, Electrocardiography, Genetic Predisposition to Disease, Humans, Infant, Long QT Syndrome, Male, Mutation, Myocytes, Cardiac, Switzerland
Added April 18, 2017
0 Communities
1 Members
0 Resources
12 MeSH Terms
Spectrum and Prevalence of CALM1-, CALM2-, and CALM3-Encoded Calmodulin Variants in Long QT Syndrome and Functional Characterization of a Novel Long QT Syndrome-Associated Calmodulin Missense Variant, E141G.
Boczek NJ, Gomez-Hurtado N, Ye D, Calvert ML, Tester DJ, Kryshtal D, Hwang HS, Johnson CN, Chazin WJ, Loporcaro CG, Shah M, Papez AL, Lau YR, Kanter R, Knollmann BC, Ackerman MJ
(2016) Circ Cardiovasc Genet 9: 136-146
MeSH Terms: Amino Acid Sequence, Animals, Calmodulin, Demography, Female, Humans, Long QT Syndrome, Male, Mice, Inbred C57BL, Mutation, Missense, Prevalence, Young Adult
Added April 18, 2017
0 Communities
1 Members
0 Resources
12 MeSH Terms
Arrhythmogenic Calmodulin Mutations Affect the Activation and Termination of Cardiac Ryanodine Receptor-mediated Ca2+ Release.
Søndergaard MT, Tian X, Liu Y, Wang R, Chazin WJ, Chen SR, Overgaard MT
(2015) J Biol Chem 290: 26151-62
MeSH Terms: Arrhythmias, Cardiac, Calcium, Calmodulin, HEK293 Cells, Humans, Mutation, Myocardium, Ryanodine Receptor Calcium Release Channel
Added March 11, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Differential CaMKII regulation by voltage-gated calcium channels in the striatum.
Pasek JG, Wang X, Colbran RJ
(2015) Mol Cell Neurosci 68: 234-43
MeSH Terms: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester, Animals, Calcium, Calcium Channel Agonists, Calcium Channel Blockers, Calcium Channels, L-Type, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Chelating Agents, Corpus Striatum, Egtazic Acid, Enzyme Inhibitors, Gene Expression Regulation, In Vitro Techniques, Male, Mice, Mice, Inbred C57BL, Pyrroles, Receptors, Glutamate, Signal Transduction, Spider Venoms
Added February 15, 2016
0 Communities
1 Members
0 Resources
20 MeSH Terms
Optogenetic versus electrical stimulation of dopamine terminals in the nucleus accumbens reveals local modulation of presynaptic release.
Melchior JR, Ferris MJ, Stuber GD, Riddle DR, Jones SR
(2015) J Neurochem 134: 833-44
MeSH Terms: Acetylcholine, Animals, Artifacts, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Channelrhodopsins, Cholinergic Neurons, Dopamine, Dopaminergic Neurons, Electric Stimulation, GABA-B Receptor Antagonists, GABAergic Neurons, Gene Knock-In Techniques, Interneurons, Male, Mice, Mice, Inbred C57BL, Microelectrodes, Nerve Tissue Proteins, Nucleus Accumbens, Optogenetics, Phosphinic Acids, Presynaptic Terminals, Promoter Regions, Genetic, Propanolamines, Synapses, Tyrosine 3-Monooxygenase, Ventral Tegmental Area, gamma-Aminobutyric Acid
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Quantitative proteomics analysis of CaMKII phosphorylation and the CaMKII interactome in the mouse forebrain.
Baucum AJ, Shonesy BC, Rose KL, Colbran RJ
(2015) ACS Chem Neurosci 6: 615-31
MeSH Terms: Animals, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Cell Membrane, Cytosol, Gene Knock-In Techniques, HEK293 Cells, Holoenzymes, Humans, Immunoprecipitation, Male, Mass Spectrometry, Mice, Transgenic, Phosphorylation, Prosencephalon, Proteomics, Recombinant Proteins, Sf9 Cells, Spodoptera, Synapses
Added February 15, 2016
0 Communities
1 Members
0 Resources
19 MeSH Terms
Novel calmodulin mutations associated with congenital arrhythmia susceptibility.
Makita N, Yagihara N, Crotti L, Johnson CN, Beckmann BM, Roh MS, Shigemizu D, Lichtner P, Ishikawa T, Aiba T, Homfray T, Behr ER, Klug D, Denjoy I, Mastantuono E, Theisen D, Tsunoda T, Satake W, Toda T, Nakagawa H, Tsuji Y, Tsuchiya T, Yamamoto H, Miyamoto Y, Endo N, Kimura A, Ozaki K, Motomura H, Suda K, Tanaka T, Schwartz PJ, Meitinger T, Kääb S, Guicheney P, Shimizu W, Bhuiyan ZA, Watanabe H, Chazin WJ, George AL
(2014) Circ Cardiovasc Genet 7: 466-74
MeSH Terms: Adrenergic beta-Antagonists, Adult, Age of Onset, Amino Acid Sequence, Calcium, Calmodulin, Child, Child, Preschool, Electrocardiography, Female, Genetic Predisposition to Disease, High-Throughput Nucleotide Sequencing, Humans, Infant, Long QT Syndrome, Male, Molecular Sequence Data, Mutation, Missense, Pedigree, Protein Binding, Sequence Analysis, DNA, Tachycardia, Ventricular
Added January 20, 2015
0 Communities
1 Members
0 Resources
22 MeSH Terms
Inhibition of pancreatic β-cell Ca2+/calmodulin-dependent protein kinase II reduces glucose-stimulated calcium influx and insulin secretion, impairing glucose tolerance.
Dadi PK, Vierra NC, Ustione A, Piston DW, Colbran RJ, Jacobson DA
(2014) J Biol Chem 289: 12435-45
MeSH Terms: Action Potentials, Animals, Biological Transport, Blotting, Western, Calcium, Calcium Channels, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Cells, Cultured, Cytoplasm, Doxycycline, Endoplasmic Reticulum, Glucose, Glucose Intolerance, Green Fluorescent Proteins, Homeostasis, Insulin, Insulin Secretion, Insulin-Secreting Cells, Mice, Mice, Inbred C57BL, Mice, Transgenic, Microscopy, Confocal, Patch-Clamp Techniques, Peptides, Potassium Channels
Added March 20, 2014
1 Communities
5 Members
0 Resources
25 MeSH Terms