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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 64

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Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects.
Machado RD, Southgate L, Eichstaedt CA, Aldred MA, Austin ED, Best DH, Chung WK, Benjamin N, Elliott CG, Eyries M, Fischer C, Gräf S, Hinderhofer K, Humbert M, Keiles SB, Loyd JE, Morrell NW, Newman JH, Soubrier F, Trembath RC, Viales RR, Grünig E
(2015) Hum Mutat 36: 1113-27
MeSH Terms: Animals, Bone Morphogenetic Protein Receptors, Type II, Disease Models, Animal, Genetic Association Studies, Genetic Counseling, Genetic Predisposition to Disease, Genetic Variation, High-Throughput Nucleotide Sequencing, Humans, Hypertension, Pulmonary, Multigene Family, Mutation, Signal Transduction, Transforming Growth Factor beta
Added February 21, 2017
0 Communities
1 Members
0 Resources
14 MeSH Terms
Heterozygous null bone morphogenetic protein receptor type 2 mutations promote SRC kinase-dependent caveolar trafficking defects and endothelial dysfunction in pulmonary arterial hypertension.
Prewitt AR, Ghose S, Frump AL, Datta A, Austin ED, Kenworthy AK, de Caestecker MP
(2015) J Biol Chem 290: 960-71
MeSH Terms: Animals, Bone Morphogenetic Protein 2, Bone Morphogenetic Protein Receptors, Type II, Caveolae, Caveolin 1, Endocytosis, Endothelial Cells, Familial Primary Pulmonary Hypertension, Frameshift Mutation, Heterozygote, Humans, Lung, Mice, Protein Transport, Pyrimidines, src-Family Kinases
Added January 6, 2015
1 Communities
3 Members
0 Resources
16 MeSH Terms
BMPR2 loss in fibroblasts promotes mammary carcinoma metastasis via increased inflammation.
Pickup MW, Hover LD, Polikowsky ER, Chytil A, Gorska AE, Novitskiy SV, Moses HL, Owens P
(2015) Mol Oncol 9: 179-91
MeSH Terms: Animals, Bone Morphogenetic Protein Receptors, Type II, Breast Neoplasms, Female, Fibroblasts, Gene Deletion, Humans, Inflammation, Mammary Neoplasms, Experimental, Mice, Neoplasm Metastasis, Tumor Suppressor Proteins
Added February 5, 2016
1 Communities
1 Members
0 Resources
12 MeSH Terms
Genetics of pulmonary hypertension.
Best DH, Austin ED, Chung WK, Elliott CG
(2014) Curr Opin Cardiol 29: 520-7
MeSH Terms: Bone Morphogenetic Protein Receptors, Type II, Familial Primary Pulmonary Hypertension, Genetic Predisposition to Disease, Genetic Testing, Humans, Mutation
Added February 12, 2015
0 Communities
1 Members
0 Resources
6 MeSH Terms
The genetics of pulmonary arterial hypertension.
Austin ED, Loyd JE
(2014) Circ Res 115: 189-202
MeSH Terms: Alleles, Animals, Bone Morphogenetic Protein Receptors, Type II, Caveolin 1, Epigenesis, Genetic, Familial Primary Pulmonary Hypertension, Genetic Testing, Gonadal Steroid Hormones, Humans, Hypertension, Pulmonary, Mutation, Nerve Tissue Proteins, Potassium Channels, Tandem Pore Domain, Protein Precursors, Protein-Serine-Threonine Kinases
Added February 12, 2015
0 Communities
2 Members
0 Resources
15 MeSH Terms
Elevation of plasma cell-free hemoglobin in pulmonary arterial hypertension.
Brittain EL, Janz DR, Austin ED, Bastarache JA, Wheeler LA, Ware LB, Hemnes AR
(2014) Chest 146: 1478-1485
MeSH Terms: Adult, Aged, Biomarkers, Bone Morphogenetic Protein Receptors, Type II, Case-Control Studies, Female, Hemodynamics, Hemoglobins, Humans, Hypertension, Pulmonary, Kaplan-Meier Estimate, Male, Middle Aged, Plasma Cells, Prognosis, Proportional Hazards Models, Retrospective Studies, Sensitivity and Specificity, Severity of Illness Index, Statistics, Nonparametric, Vascular Resistance
Added August 8, 2014
0 Communities
3 Members
0 Resources
21 MeSH Terms
Rescuing the BMPR2 signaling axis in pulmonary arterial hypertension.
West J, Austin E, Fessel JP, Loyd J, Hamid R
(2014) Drug Discov Today 19: 1241-5
MeSH Terms: Animals, Bone Morphogenetic Protein Receptors, Type II, Humans, Hypertension, Pulmonary, Signal Transduction
Added May 20, 2014
0 Communities
5 Members
0 Resources
5 MeSH Terms
BMP pathway regulation of and by macrophages.
Talati M, West J, Zaynagetdinov R, Hong CC, Han W, Blackwell T, Robinson L, Blackwell TS, Lane K
(2014) PLoS One 9: e94119
MeSH Terms: Animals, Bone Morphogenetic Protein Receptors, Type II, Cells, Cultured, Coculture Techniques, Hypertension, Pulmonary, Macrophages, Mice, Mice, Transgenic, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, Signal Transduction, Smad Proteins
Added April 10, 2014
2 Communities
3 Members
0 Resources
12 MeSH Terms
Functional prostacyclin synthase promoter polymorphisms. Impact in pulmonary arterial hypertension.
Stearman RS, Cornelius AR, Lu X, Conklin DS, Del Rosario MJ, Lowe AM, Elos MT, Fettig LM, Wong RE, Hara N, Cogan JD, Phillips JA, Taylor MR, Graham BB, Tuder RM, Loyd JE, Geraci MW
(2014) Am J Respir Crit Care Med 189: 1110-20
MeSH Terms: Bone Morphogenetic Protein Receptors, Type II, Case-Control Studies, Cytochrome P-450 Enzyme System, Disease Progression, Familial Primary Pulmonary Hypertension, Female, Haplotypes, Heterozygote, Humans, Hypertension, Pulmonary, Intramolecular Oxidoreductases, Male, Mutation, Polymerase Chain Reaction, Polymorphism, Genetic
Added March 20, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Genetics and genomics of pulmonary arterial hypertension.
Soubrier F, Chung WK, Machado R, Grünig E, Aldred M, Geraci M, Loyd JE, Elliott CG, Trembath RC, Newman JH, Humbert M
(2013) J Am Coll Cardiol 62: D13-21
MeSH Terms: Animals, Bone Morphogenetic Protein Receptors, Type II, Familial Primary Pulmonary Hypertension, Genetic Predisposition to Disease, Genome-Wide Association Study, Genomics, Humans, Hypertension, Pulmonary, Mutation
Added March 20, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms