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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 34

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Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs.
Lawson WE, Cheng DS, Degryse AL, Tanjore H, Polosukhin VV, Xu XC, Newcomb DC, Jones BR, Roldan J, Lane KB, Morrisey EE, Beers MF, Yull FE, Blackwell TS
(2011) Proc Natl Acad Sci U S A 108: 10562-7
MeSH Terms: Animals, Apoptosis, Bleomycin, Endoplasmic Reticulum, Intercellular Signaling Peptides and Proteins, Lung, Mice, Mice, Transgenic, Mutation, Peptides, Pulmonary Fibrosis, Pulmonary Surfactant-Associated Protein C, Reverse Transcriptase Polymerase Chain Reaction, Tunicamycin
Added February 26, 2013
3 Communities
3 Members
0 Resources
14 MeSH Terms
Progress toward improving animal models for idiopathic pulmonary fibrosis.
Degryse AL, Lawson WE
(2011) Am J Med Sci 341: 444-9
MeSH Terms: Animals, Bleomycin, Disease Models, Animal, Fluorescein-5-isothiocyanate, Idiopathic Pulmonary Fibrosis, Radiation Injuries, Experimental, Silicon Dioxide
Added May 27, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment.
Degryse AL, Tanjore H, Xu XC, Polosukhin VV, Jones BR, Boomershine CS, Ortiz C, Sherrill TP, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE
(2011) Am J Physiol Lung Cell Mol Physiol 300: L887-97
MeSH Terms: Animals, Antibiotics, Antineoplastic, Bleomycin, Blotting, Western, Cell Proliferation, Cells, Cultured, Disease Models, Animal, Epithelium, Fibroblasts, Fluorescent Antibody Technique, Lung Injury, Mice, Mice, Transgenic, Pneumonia, Protein Serine-Threonine Kinases, Pulmonary Alveoli, Pulmonary Fibrosis, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, Transforming Growth Factor beta, beta-Galactosidase
Added March 5, 2014
1 Communities
2 Members
0 Resources
22 MeSH Terms
The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation.
Jun D, Garat C, West J, Thorn N, Chow K, Cleaver T, Sullivan T, Torchia EC, Childs C, Shade T, Tadjali M, Lara A, Nozik-Grayck E, Malkoski S, Sorrentino B, Meyrick B, Klemm D, Rojas M, Wagner DH, Majka SM
(2011) Stem Cells 29: 725-35
MeSH Terms: Animals, Bleomycin, Cell Proliferation, Familial Primary Pulmonary Hypertension, Hypertension, Pulmonary, Lung Injury, Mesenchymal Stem Cells, Mice, Mice, Inbred C57BL, Polymerase Chain Reaction, Pulmonary Fibrosis, T-Lymphocytes
Added August 4, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis.
McCann MR, Monemdjou R, Ghassemi-Kakroodi P, Fahmi H, Perez G, Liu S, Shi-Wen X, Parapuram SK, Kojima F, Denton CP, Abraham DJ, Martel-Pelletier J, Crofford LJ, Leask A, Kapoor M
(2011) Arthritis Res Ther 13: R6
MeSH Terms: Animals, Antibiotics, Antineoplastic, Bleomycin, Blotting, Western, Disease Models, Animal, Female, Fibroblasts, Fibrosis, Fluorescent Antibody Technique, Immunohistochemistry, Intramolecular Oxidoreductases, Male, Mice, Mice, Knockout, Prostaglandin-E Synthases, Scleroderma, Systemic
Added September 18, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis.
Degryse AL, Tanjore H, Xu XC, Polosukhin VV, Jones BR, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE
(2010) Am J Physiol Lung Cell Mol Physiol 299: L442-52
MeSH Terms: Animals, Antibiotics, Antineoplastic, Apoptosis, Bleomycin, Bronchoalveolar Lavage Fluid, Cell Proliferation, Cells, Cultured, Disease Models, Animal, Epithelial Cells, Fibroblasts, Fluorescent Antibody Technique, Humans, Idiopathic Pulmonary Fibrosis, Immunoenzyme Techniques, In Situ Nick-End Labeling, Integrases, Intubation, Intratracheal, Mesoderm, Mice, Mice, Inbred C57BL, Mice, Transgenic, beta-Galactosidase
Added March 5, 2014
1 Communities
2 Members
0 Resources
22 MeSH Terms
Lung extracellular superoxide dismutase overexpression lessens bleomycin-induced pulmonary hypertension and vascular remodeling.
Van Rheen Z, Fattman C, Domarski S, Majka S, Klemm D, Stenmark KR, Nozik-Grayck E
(2011) Am J Respir Cell Mol Biol 44: 500-8
MeSH Terms: Animals, Bleomycin, Cell Proliferation, Early Growth Response Protein 1, Extracellular Space, Gene Expression Regulation, Humans, Hypertension, Pulmonary, Lung, Mice, Mice, Inbred C57BL, Mice, Transgenic, Nitric Oxide Synthase Type III, Nitrosation, Oxidation-Reduction, Pulmonary Artery, Pulmonary Fibrosis, Stress, Physiological, Superoxide Dismutase, Transforming Growth Factor beta, Tyrosine
Added August 4, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Autologous stem cell transplant in a patient with Down syndrome and relapsed Hodgkin lymphoma.
Eckrich MJ, Domm J, Ho R, Whitlock JA, Frangoul H
(2009) Pediatr Blood Cancer 53: 1327-8
MeSH Terms: Antineoplastic Combined Chemotherapy Protocols, Bleomycin, Carmustine, Child, Combined Modality Therapy, Cyclophosphamide, Down Syndrome, Doxorubicin, Etoposide, Granulocyte Colony-Stimulating Factor, Hodgkin Disease, Humans, Ifosfamide, Male, Mesna, Peripheral Blood Stem Cell Transplantation, Prednisone, Procarbazine, Recurrence, Remission Induction, Transplantation Conditioning, Transplantation, Autologous, Vinblastine, Vincristine, Vinorelbine
Added March 5, 2014
1 Communities
2 Members
0 Resources
25 MeSH Terms
Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis.
Tanjore H, Xu XC, Polosukhin VV, Degryse AL, Li B, Han W, Sherrill TP, Plieth D, Neilson EG, Blackwell TS, Lawson WE
(2009) Am J Respir Crit Care Med 180: 657-65
MeSH Terms: Animals, Antibiotics, Antineoplastic, Bleomycin, Blotting, Western, Cell Culture Techniques, Disease Models, Animal, Epithelial Cells, Epithelium, Fibroblasts, Mesoderm, Mice, Mice, Transgenic, Pulmonary Alveoli, Pulmonary Fibrosis
Added March 5, 2014
1 Communities
2 Members
0 Resources
14 MeSH Terms
Tandem mass spectrometry-based detection of c4'-oxidized abasic sites at specific positions in DNA fragments.
Chowdhury G, Guengerich FP
(2009) Chem Res Toxicol 22: 1310-9
MeSH Terms: Antineoplastic Agents, Base Sequence, Bleomycin, Chromatography, High Pressure Liquid, DNA, DNA Damage, Hydroxyl Radical, Ions, Oligonucleotides, Oxidation-Reduction, Radiation, Ionizing, Spectrometry, Mass, Electrospray Ionization, Tandem Mass Spectrometry
Added March 7, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms