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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 145

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2-arachidonoylglycerol signaling impairs short-term fear extinction.
Hartley ND, Gunduz-Cinar O, Halladay L, Bukalo O, Holmes A, Patel S
(2016) Transl Psychiatry 6: e749
MeSH Terms: Animals, Arachidonic Acids, Behavior, Animal, Cannabinoid Receptor Agonists, Endocannabinoids, Extinction, Psychological, Fear, Glycerides, Male, Mice, Mice, Inbred C57BL, Signal Transduction
Added March 14, 2018
0 Communities
1 Members
0 Resources
12 MeSH Terms
Fluoxetine Facilitates Fear Extinction Through Amygdala Endocannabinoids.
Gunduz-Cinar O, Flynn S, Brockway E, Kaugars K, Baldi R, Ramikie TS, Cinar R, Kunos G, Patel S, Holmes A
(2016) Neuropsychopharmacology 41: 1598-609
MeSH Terms: Amidohydrolases, Amygdala, Animals, Anti-Anxiety Agents, Arachidonic Acids, Endocannabinoids, Extinction, Psychological, Fear, Fluoxetine, Male, Mice, Mice, Inbred Strains, Polyunsaturated Alkamides
Added March 14, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
Competition and allostery govern substrate selectivity of cyclooxygenase-2.
Mitchener MM, Hermanson DJ, Shockley EM, Brown HA, Lindsley CW, Reese J, Rouzer CA, Lopez CF, Marnett LJ
(2015) Proc Natl Acad Sci U S A 112: 12366-71
MeSH Terms: Algorithms, Allosteric Regulation, Allosteric Site, Animals, Arachidonic Acid, Arachidonic Acids, Binding, Competitive, Catalytic Domain, Cell Line, Computer Simulation, Cyclooxygenase 2, Endocannabinoids, Glycerides, Kinetics, Macrophages, Mice, Oxidation-Reduction, Prostaglandins, Protein Binding, Protein Multimerization, Sf9 Cells, Spodoptera, Substrate Specificity, Zymosan
Added February 15, 2016
1 Communities
4 Members
0 Resources
24 MeSH Terms
The Anxiolytic Actions of 2-Arachidonoylglycerol: Converging Evidence From Two Recent Genetic Endocannabinoid Deficiency Models.
Patel S, Shonesy BC, Bluett RJ, Winder DG, Colbran RJ
(2016) Biol Psychiatry 79: e78-e79
MeSH Terms: Anti-Anxiety Agents, Arachidonic Acids, Endocannabinoids, Glycerides, Humans
Added February 15, 2016
0 Communities
3 Members
0 Resources
5 MeSH Terms
Neurobiological Interactions Between Stress and the Endocannabinoid System.
Morena M, Patel S, Bains JS, Hill MN
(2016) Neuropsychopharmacology 41: 80-102
MeSH Terms: Animals, Arachidonic Acids, Cannabinoid Receptor Modulators, Endocannabinoids, Glycerides, Humans, Hypothalamo-Hypophyseal System, Pituitary-Adrenal System, Polyunsaturated Alkamides, Receptor, Cannabinoid, CB1, Receptor, Cannabinoid, CB2, Stress, Psychological
Added March 14, 2018
0 Communities
1 Members
0 Resources
12 MeSH Terms
Corticotropin-releasing hormone drives anandamide hydrolysis in the amygdala to promote anxiety.
Gray JM, Vecchiarelli HA, Morena M, Lee TT, Hermanson DJ, Kim AB, McLaughlin RJ, Hassan KI, Kühne C, Wotjak CT, Deussing JM, Patel S, Hill MN
(2015) J Neurosci 35: 3879-92
MeSH Terms: Adrenocorticotropic Hormone, Amidohydrolases, Amygdala, Animals, Anxiety, Arachidonic Acids, Corticotropin-Releasing Hormone, Endocannabinoids, Hydrolysis, Male, Mice, Mice, Knockout, Polyunsaturated Alkamides, Rats, Rats, Sprague-Dawley, Receptors, Corticotropin-Releasing Hormone, Stress, Psychological
Added March 14, 2018
0 Communities
1 Members
0 Resources
17 MeSH Terms
13-Methylarachidonic acid is a positive allosteric modulator of endocannabinoid oxygenation by cyclooxygenase.
Kudalkar SN, Nikas SP, Kingsley PJ, Xu S, Galligan JJ, Rouzer CA, Banerjee S, Ji L, Eno MR, Makriyannis A, Marnett LJ
(2015) J Biol Chem 290: 7897-909
MeSH Terms: Allosteric Regulation, Arachidonic Acids, Endocannabinoids, Kinetics, Oxygen, Prostaglandin-Endoperoxide Synthases
Added February 22, 2016
0 Communities
3 Members
0 Resources
6 MeSH Terms
The initiation of synaptic 2-AG mobilization requires both an increased supply of diacylglycerol precursor and increased postsynaptic calcium.
Shonesy BC, Winder DG, Patel S, Colbran RJ
(2015) Neuropharmacology 91: 57-62
MeSH Terms: Animals, Arachidonic Acids, Calcium Signaling, Corpus Striatum, Diglycerides, Endocannabinoids, Glycerides, Mice, Mice, Inbred C57BL, Mice, Inbred ICR, Neurons, Synapses
Added January 20, 2015
0 Communities
2 Members
0 Resources
12 MeSH Terms
Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation.
Shonesy BC, Bluett RJ, Ramikie TS, Báldi R, Hermanson DJ, Kingsley PJ, Marnett LJ, Winder DG, Colbran RJ, Patel S
(2014) Cell Rep 9: 1644-1653
MeSH Terms: Amygdala, Animals, Anxiety, Arachidonic Acids, Depression, Disease Models, Animal, Endocannabinoids, Female, Glutamic Acid, Glycerides, Male, Mice, Knockout, Synaptic Transmission
Added January 20, 2015
1 Communities
4 Members
0 Resources
13 MeSH Terms
Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells.
Manna JD, Wepy JA, Hsu KL, Chang JW, Cravatt BF, Marnett LJ
(2014) J Biol Chem 289: 33741-53
MeSH Terms: Animals, Arachidonic Acids, Cell Line, Tumor, Cyclooxygenase 2, Endocannabinoids, Escherichia coli, Esters, Gene Expression Regulation, Neoplastic, Glycerides, Glycerol, Humans, Hydrolysis, Kinetics, Macrophages, Mice, Polyunsaturated Alkamides, Prostaglandins, RNA, Small Interfering, Recombinant Proteins, Signal Transduction, Substrate Specificity, Thiolester Hydrolases
Added February 22, 2016
0 Communities
1 Members
0 Resources
22 MeSH Terms