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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 74

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Hsp90 inhibitors promote p53-dependent apoptosis through PUMA and Bax.
He K, Zheng X, Zhang L, Yu J
(2013) Mol Cancer Ther 12: 2559-68
MeSH Terms: Animals, Apoptosis, Apoptosis Regulatory Proteins, Benzoquinones, Cell Line, Tumor, Colorectal Neoplasms, DNA Damage, HCT116 Cells, HSP90 Heat-Shock Proteins, Humans, Isoxazoles, Lactams, Macrocyclic, Mice, Mice, Nude, Mitochondria, Proto-Oncogene Proteins, Resorcinols, Tumor Suppressor Protein p53, Xenograft Model Antitumor Assays, bcl-2-Associated X Protein
Added July 28, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Autophagy mediates paracrine regulation of vascular endothelial cells.
Kim KW, Paul P, Qiao J, Chung DH
(2013) Lab Invest 93: 639-45
MeSH Terms: Apoptosis Regulatory Proteins, Autophagy, Autophagy-Related Protein 5, Beclin-1, Cell Proliferation, Coculture Techniques, Endothelial Cells, Endothelium, Vascular, Gastrin-Releasing Peptide, Gene Expression Regulation, Human Umbilical Vein Endothelial Cells, Humans, Membrane Proteins, Microtubule-Associated Proteins, Neovascularization, Pathologic, Paracrine Communication, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Signal Transduction, TOR Serine-Threonine Kinases
Added March 7, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Function of death-associated protein 1 in proliferation, differentiation, and apoptosis of chicken satellite cells.
Shin J, McFarland DC, Strasburg GM, Velleman SG
(2013) Muscle Nerve 48: 777-90
MeSH Terms: Animals, Apoptosis, Apoptosis Regulatory Proteins, Cell Differentiation, Cell Proliferation, Cells, Cultured, Chickens, Genetic Vectors, Muscle Development, Muscle, Skeletal, Satellite Cells, Skeletal Muscle, Transfection
Added March 3, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
The ubiquitin ligase Mindbomb 1 coordinates gastrointestinal secretory cell maturation.
Capoccia BJ, Jin RU, Kong YY, Peek RM, Fassan M, Rugge M, Mills JC
(2013) J Clin Invest 123: 1475-91
MeSH Terms: Adenocarcinoma, Animals, Apoptosis Regulatory Proteins, Base Sequence, Basic Helix-Loop-Helix Transcription Factors, Calcium-Calmodulin-Dependent Protein Kinases, Cell Differentiation, Cell Enlargement, Cell Polarity, Chief Cells, Gastric, Conserved Sequence, Death-Associated Protein Kinases, Humans, Intestinal Neoplasms, Metaplasia, Mice, Mice, Knockout, Microtubules, Protein Transport, Stomach, Tamoxifen, Ubiquitin-Protein Ligases
Added September 3, 2013
0 Communities
2 Members
0 Resources
22 MeSH Terms
Crizotinib induces PUMA-dependent apoptosis in colon cancer cells.
Zheng X, He K, Zhang L, Yu J
(2013) Mol Cancer Ther 12: 777-86
MeSH Terms: Animals, Antineoplastic Agents, Apoptosis, Apoptosis Regulatory Proteins, Cell Line, Tumor, Colonic Neoplasms, Crizotinib, Drug Synergism, Female, Gefitinib, Gene Expression Regulation, Neoplastic, Humans, Mice, Niacinamide, Phenylurea Compounds, Protein Kinase Inhibitors, Proto-Oncogene Proteins, Pyrazoles, Pyridines, Quinazolines, Sorafenib, Tumor Suppressor Protein p53, Xenograft Model Antitumor Assays
Added July 28, 2015
0 Communities
1 Members
0 Resources
23 MeSH Terms
The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737.
Boiani M, Daniel C, Liu X, Hogarty MD, Marnett LJ
(2013) J Biol Chem 288: 6980-90
MeSH Terms: Adaptor Proteins, Signal Transducing, Antineoplastic Agents, Apoptosis, Apoptosis Regulatory Proteins, Biphenyl Compounds, Cell Line, Tumor, Cell Survival, Drug Resistance, Neoplasm, Gene Expression Regulation, Neoplastic, HEK293 Cells, Humans, Immunoblotting, Myeloid Cell Leukemia Sequence 1 Protein, Neoplasms, Nitrophenols, Piperazines, Proteasome Endopeptidase Complex, Protein Binding, Protein Stability, Proteolysis, Proto-Oncogene Proteins c-bcl-2, RNA Interference, Reverse Transcriptase Polymerase Chain Reaction, Sulfonamides, Ubiquitination
Added March 7, 2014
0 Communities
1 Members
0 Resources
25 MeSH Terms
CITED1 expression in liver development and hepatoblastoma.
Murphy AJ, de Caestecker C, Pierce J, Boyle SC, Ayers GD, Zhao Z, Libes JM, Correa H, Walter T, Huppert SS, Perantoni AO, de Caestecker MP, Lovvorn HN
(2012) Neoplasia 14: 1153-63
MeSH Terms: Animals, Apoptosis Regulatory Proteins, Cell Line, Tumor, Cell Proliferation, DNA-Binding Proteins, Embryo, Mammalian, Hepatoblastoma, Humans, Liver, Liver Neoplasms, Liver Regeneration, Membrane Proteins, Mice, Mutation, Nuclear Proteins, RNA, Messenger, Time Factors, Trans-Activators, Transcription Factors, Wnt Signaling Pathway, beta Catenin
Added January 10, 2014
2 Communities
5 Members
0 Resources
21 MeSH Terms
Age-related susceptibility to apoptosis in human retinal pigment epithelial cells is triggered by disruption of p53-Mdm2 association.
Bhattacharya S, Chaum E, Johnson DA, Johnson LR
(2012) Invest Ophthalmol Vis Sci 53: 8350-66
MeSH Terms: Acetylation, Adult, Aged, Aged, 80 and over, Aging, Apoptosis, Apoptosis Regulatory Proteins, Benzamides, Blotting, Western, Caspase 3, Cell Proliferation, Cells, Cultured, DNA Fragmentation, Disease Susceptibility, Enzyme-Linked Immunosorbent Assay, Fluorescent Antibody Technique, Indirect, Humans, Imidazoles, In Situ Nick-End Labeling, Middle Aged, Naphthols, Phosphorylation, Piperazines, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-mdm2, RNA, Small Interfering, Retinal Pigment Epithelium, Sirtuin 1, Sirtuin 2, Tumor Suppressor Protein p53
Added June 11, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death.
Ko DC, Gamazon ER, Shukla KP, Pfuetzner RA, Whittington D, Holden TD, Brittnacher MJ, Fong C, Radey M, Ogohara C, Stark AL, Akey JM, Dolan ME, Wurfel MM, Miller SI
(2012) Proc Natl Acad Sci U S A 109: E2343-52
MeSH Terms: Adult, Aged, Aged, 80 and over, Animals, Apoptosis, Apoptosis Regulatory Proteins, Bone Marrow Cells, Caspase 1, Caspase 9, Deoxyadenosines, Genetic Predisposition to Disease, Genetic Variation, HEK293 Cells, HapMap Project, Humans, Methionine, Mice, Mice, Inbred C57BL, Middle Aged, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Salmonella Infections, Salmonella typhimurium, Thionucleosides, Young Adult
Added April 13, 2017
0 Communities
1 Members
0 Resources
25 MeSH Terms
SIX2 and CITED1, markers of nephronic progenitor self-renewal, remain active in primitive elements of Wilms' tumor.
Murphy AJ, Pierce J, de Caestecker C, Taylor C, Anderson JR, Perantoni AO, de Caestecker MP, Lovvorn HN
(2012) J Pediatr Surg 47: 1239-49
MeSH Terms: Apoptosis Regulatory Proteins, Biomarkers, Tumor, Blotting, Western, Cell Nucleus, Cytosol, Gene Expression Regulation, Neoplastic, Homeodomain Proteins, Humans, Immunoenzyme Techniques, Kidney, Kidney Neoplasms, Microscopy, Fluorescence, Neoplasm Proteins, Neoplastic Stem Cells, Nephrons, Nerve Tissue Proteins, Nuclear Proteins, Prognosis, RNA, Messenger, RNA, Neoplasm, Reverse Transcriptase Polymerase Chain Reaction, Single-Blind Method, Trans-Activators, Transcription Factors, Wilms Tumor
Added January 28, 2014
2 Communities
3 Members
0 Resources
25 MeSH Terms