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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 85

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Monitoring cholinergic activity during attentional performance in mice heterozygous for the choline transporter: a model of cholinergic capacity limits.
Paolone G, Mallory CS, Cherian AK, Miller TR, Blakely RD, Sarter M
(2013) Neuropharmacology 75: 274-85
MeSH Terms: Acetylcholine, Alkaloids, Animals, Atropine, Attention, Azocines, Cholinergic Antagonists, Conditioning, Operant, Female, Humans, Male, Mecamylamine, Membrane Transport Proteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Protein Binding, Quinolizines, Sodium Channel Blockers, Tetrodotoxin, Tritium
Added September 28, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Development of myelination and cholinergic innervation in the central auditory system of a prosimian primate (Otolemur garnetti).
Miller DJ, Lackey EP, Hackett TA, Kaas JH
(2013) J Comp Neurol 521: 3804-16
MeSH Terms: Acetylcholine, Acetylcholinesterase, Age Factors, Animals, Animals, Newborn, Auditory Cortex, Auditory Pathways, Brain Mapping, Cell Count, Geniculate Bodies, Inferior Colliculi, Myelin Sheath, Stereotaxic Techniques, Strepsirhini
Added February 22, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
The presynaptic choline transporter imposes limits on sustained cortical acetylcholine release and attention.
Parikh V, St Peters M, Blakely RD, Sarter M
(2013) J Neurosci 33: 2326-37
MeSH Terms: Acetylcholine, Animals, Attention, Female, Male, Membrane Transport Proteins, Mice, Mice, Inbred C57BL, Mice, Transgenic, Presynaptic Terminals, Random Allocation
Added July 10, 2013
1 Communities
1 Members
0 Resources
11 MeSH Terms
Further exploration of M₁ allosteric agonists: subtle structural changes abolish M₁ allosteric agonism and result in pan-mAChR orthosteric antagonism.
Sheffler DJ, Sevel C, Le U, Lovell KM, Tarr JC, Carrington SJ, Cho HP, Digby GJ, Niswender CM, Conn PJ, Hopkins CR, Wood MR, Lindsley CW
(2013) Bioorg Med Chem Lett 23: 223-7
MeSH Terms: Acetylcholine, Allosteric Regulation, Allosteric Site, Animals, Benzamides, Benzimidazoles, CHO Cells, Calcium, Cricetinae, Cricetulus, Humans, Piperidines, Rats, Receptor, Muscarinic M1, Receptors, Muscarinic, Structure-Activity Relationship, Transfection
Added March 7, 2014
1 Communities
3 Members
0 Resources
17 MeSH Terms
Synthesis and biological characterization of a series of novel diaryl amide M₁ antagonists.
Poslusney MS, Sevel C, Utley TJ, Bridges TM, Morrison RD, Kett NR, Sheffler DJ, Niswender CM, Daniels JS, Conn PJ, Lindsley CW, Wood MR
(2012) Bioorg Med Chem Lett 22: 6923-8
MeSH Terms: Acetylcholine, Amides, Animals, Binding, Competitive, CHO Cells, Cricetinae, Cricetulus, Humans, Piperazines, Receptor, Muscarinic M1, Stereoisomerism, Stilbenes, Structure-Activity Relationship
Added March 7, 2014
1 Communities
3 Members
0 Resources
13 MeSH Terms
Cognitive effects of dopamine depletion in the context of diminished acetylcholine signaling capacity in mice.
Zurkovsky L, Bychkov E, Tsakem EL, Siedlecki C, Blakely RD, Gurevich EV
(2013) Dis Model Mech 6: 171-83
MeSH Terms: Acetylcholine, Animals, Cholinergic Agents, Cognition Disorders, Dementia, Disease Models, Animal, Dopamine, Hemicholinium 3, Humans, Male, Membrane Transport Proteins, Memory, Mice, Mice, Inbred C57BL, Mice, Knockout, Parkinsonian Disorders, Signal Transduction
Added July 10, 2013
1 Communities
1 Members
0 Resources
17 MeSH Terms
Muscarinic receptor pharmacology and circuitry for the modulation of cognition.
Bubser M, Byun N, Wood MR, Jones CK
(2012) Handb Exp Pharmacol : 121-66
MeSH Terms: Acetylcholine, Animals, Brain, Cognition, Cognition Disorders, Humans, Muscarinic Agonists, Muscarinic Antagonists, Nootropic Agents, Receptors, Muscarinic, Signal Transduction
Added March 14, 2018
0 Communities
2 Members
0 Resources
11 MeSH Terms
Recurrent deletions and reciprocal duplications of 10q11.21q11.23 including CHAT and SLC18A3 are likely mediated by complex low-copy repeats.
Stankiewicz P, Kulkarni S, Dharmadhikari AV, Sampath S, Bhatt SS, Shaikh TH, Xia Z, Pursley AN, Cooper ML, Shinawi M, Paciorkowski AR, Grange DK, Noetzel MJ, Saunders S, Simons P, Summar M, Lee B, Scaglia F, Fellmann F, Martinet D, Beckmann JS, Asamoah A, Platky K, Sparks S, Martin AS, Madan-Khetarpal S, Hoover J, Medne L, Bonnemann CG, Moeschler JB, Vallee SE, Parikh S, Irwin P, Dalzell VP, Smith WE, Banks VC, Flannery DB, Lovell CM, Bellus GA, Golden-Grant K, Gorski JL, Kussmann JL, McGregor TL, Hamid R, Pfotenhauer J, Ballif BC, Shaw CA, Kang SH, Bacino CA, Patel A, Rosenfeld JA, Cheung SW, Shaffer LG
(2012) Hum Mutat 33: 165-79
MeSH Terms: Abnormalities, Multiple, Child, Child, Preschool, Chromosome Aberrations, Chromosome Mapping, Chromosomes, Human, Pair 10, DNA Copy Number Variations, Developmental Disabilities, Female, Genetic Variation, Homologous Recombination, Humans, In Situ Hybridization, Fluorescence, Infant, Intellectual Disability, Male, Nerve Growth Factors, Oligonucleotide Array Sequence Analysis, Penetrance, Segmental Duplications, Genomic, Sequence Deletion, Vesicular Acetylcholine Transport Proteins
Added March 27, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
The cholinergic hypothesis of cognitive aging revisited again: cholinergic functional compensation.
Dumas JA, Newhouse PA
(2011) Pharmacol Biochem Behav 99: 254-61
MeSH Terms: Acetylcholine, Aging, Alzheimer Disease, Cognition, Cognition Disorders, Humans, Models, Neurological, Models, Psychological, Nootropic Agents, Receptors, Cholinergic
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Motor neuron-specific overexpression of the presynaptic choline transporter: impact on motor endurance and evoked muscle activity.
Lund D, Ruggiero AM, Ferguson SM, Wright J, English BA, Reisz PA, Whitaker SM, Peltier AC, Blakely RD
(2010) Neuroscience 171: 1041-53
MeSH Terms: Acetylcholine, Acetylcholinesterase, Action Potentials, Animals, Animals, Newborn, Behavior, Animal, Brain, Choline O-Acetyltransferase, Electric Stimulation, Exercise Test, GPI-Linked Proteins, Gene Expression Regulation, Developmental, Green Fluorescent Proteins, Homeodomain Proteins, Membrane Transport Proteins, Mice, Mice, Transgenic, Motor Activity, Motor Neurons, Muscle, Skeletal, Nerve Tissue Proteins, Neuromuscular Junction, Statistics, Nonparametric, Synapses, Transcription Factors
Added July 11, 2013
2 Communities
3 Members
0 Resources
25 MeSH Terms