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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 11 to 20 of 43

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Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: an AIDS Clinical Trials Group study.
Ribaudo HJ, Liu H, Schwab M, Schaeffeler E, Eichelbaum M, Motsinger-Reif AA, Ritchie MD, Zanger UM, Acosta EP, Morse GD, Gulick RM, Robbins GK, Clifford D, Haas DW
(2010) J Infect Dis 202: 717-22
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, ATP Binding Cassette Transporter, Subfamily B, Member 1, African Continental Ancestry Group, Alkynes, Anti-HIV Agents, Aryl Hydrocarbon Hydroxylases, Benzoxazines, Cyclopropanes, Cytochrome P-450 CYP2B6, Cytochrome P-450 CYP3A, European Continental Ancestry Group, Female, HIV Infections, Hispanic Americans, Humans, Male, Oxidoreductases, N-Demethylating, Pharmacogenetics, Polymorphism, Single Nucleotide, Reverse Transcriptase Inhibitors, Treatment Outcome
Added March 13, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variability.
Ho RH, Leake BF, Kilkenny DM, Meyer Zu Schwabedissen HE, Glaeser H, Kroetz DL, Kim RB
(2010) Pharmacogenet Genomics 20: 45-57
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 11, ATP-Binding Cassette Transporters, Bile Acids and Salts, Cell Line, Cell Membrane, Gene Expression, HeLa Cells, Humans, Liver, Microscopy, Confocal, Mutagenesis, Site-Directed, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, RNA, Messenger, Recombinant Fusion Proteins, Vaccinia virus
Added December 5, 2013
3 Communities
2 Members
1 Resources
16 MeSH Terms
Oral cyclosporin A inhibits CD4 T cell P-glycoprotein activity in HIV-infected adults initiating treatment with nucleoside reverse transcriptase inhibitors.
Hulgan T, Donahue JP, Smeaton L, Pu M, Wang H, Lederman MM, Smith K, Valdez H, Pilcher C, Haas DW, AIDS Clinical Trials Group Study A5138 Team
(2009) Eur J Clin Pharmacol 65: 1081-8
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Adult, Anti-HIV Agents, Antiretroviral Therapy, Highly Active, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Cyclosporine, Enzyme Inhibitors, Female, Flow Cytometry, HIV Infections, Humans, Male, Middle Aged, Young Adult
Added December 10, 2013
0 Communities
2 Members
0 Resources
15 MeSH Terms
Influence of the G2677T/C3435T haplotype of MDR1 on P-glycoprotein trafficking and ibutilide-induced block of HERG.
McBride BF, Yang T, Roden DM
(2009) Pharmacogenomics J 9: 194-201
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, ATP Binding Cassette Transporter, Subfamily B, Member 1, Animals, Anti-Arrhythmia Agents, CHO Cells, Cricetinae, Cricetulus, Dose-Response Relationship, Drug, ERG1 Potassium Channel, Ether-A-Go-Go Potassium Channels, Haplotypes, Humans, Microscopy, Confocal, Microscopy, Fluorescence, Protein Transport, Sulfonamides
Added March 7, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
DeltaNp73alpha regulates MDR1 expression by inhibiting p53 function.
Vilgelm A, Wei JX, Piazuelo MB, Washington MK, Prassolov V, El-Rifai W, Zaika A
(2008) Oncogene 27: 2170-6
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, ATP Binding Cassette Transporter, Subfamily B, Member 1, Carcinoma, DNA-Binding Proteins, Down-Regulation, Gene Expression Regulation, Neoplastic, Genes, p53, Humans, Nuclear Proteins, Promoter Regions, Genetic, Protein Binding, RNA, Messenger, Stomach Neoplasms, Tumor Cells, Cultured, Tumor Suppressor Protein p53, Tumor Suppressor Proteins
Added June 14, 2013
0 Communities
4 Members
0 Resources
16 MeSH Terms
Identification and characterization of a new tubulin-binding tetrasubstituted brominated pyrrole.
Mooberry SL, Weiderhold KN, Dakshanamurthy S, Hamel E, Banner EJ, Kharlamova A, Hempel J, Gupton JT, Brown ML
(2007) Mol Pharmacol 72: 132-40
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Antineoplastic Agents, Cell Cycle, Colchicine, Drug Resistance, Neoplasm, Microtubules, Models, Molecular, Phosphorylation, Poly(ADP-ribose) Polymerases, Proto-Oncogene Proteins c-bcl-2, Pyrroles, Tubulin
Added September 16, 2013
0 Communities
1 Members
0 Resources
12 MeSH Terms
Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II.
Widder JD, Guzik TJ, Mueller CF, Clempus RE, Schmidt HH, Dikalov SI, Griendling KK, Jones DP, Harrison DG
(2007) Arterioscler Thromb Vasc Biol 27: 762-8
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Angiotensin II, Animals, Aorta, Biopterin, Blood Pressure, Endothelium, Vascular, Enzyme Inhibitors, Glutathione Disulfide, Hypertension, Isoenzymes, Male, Mice, Mice, Inbred Strains, Mice, Knockout, NADPH Oxidases, NG-Nitroarginine Methyl Ester, Nitric Oxide, Superoxides, Vasodilation
Added February 17, 2016
0 Communities
1 Members
0 Resources
20 MeSH Terms
Intestinal drug transporter expression and the impact of grapefruit juice in humans.
Glaeser H, Bailey DG, Dresser GK, Gregor JC, Schwarz UI, McGrath JS, Jolicoeur E, Lee W, Leake BF, Tirona RG, Kim RB
(2007) Clin Pharmacol Ther 81: 362-70
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Adult, Aged, Aged, 80 and over, Beverages, Biological Availability, Blotting, Western, Carrier Proteins, Citrus paradisi, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System, Female, Fluorescent Antibody Technique, Food-Drug Interactions, Histamine H1 Antagonists, Humans, Immunohistochemistry, Intestinal Mucosa, Male, Middle Aged, Organic Anion Transporters, Pharmaceutical Preparations, RNA, Reverse Transcriptase Polymerase Chain Reaction, Terfenadine
Added March 27, 2014
1 Communities
1 Members
2 Resources
25 MeSH Terms
Ritonavir, saquinavir, and efavirenz, but not nevirapine, inhibit bile acid transport in human and rat hepatocytes.
McRae MP, Lowe CM, Tian X, Bourdet DL, Ho RH, Leake BF, Kim RB, Brouwer KL, Kashuba AD
(2006) J Pharmacol Exp Ther 318: 1068-75
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 11, ATP-Binding Cassette Transporters, Adolescent, Adult, Aged, Aged, 80 and over, Alkynes, Animals, Anti-HIV Agents, Benzoxazines, Biological Transport, Cells, Cultured, Child, Cyclopropanes, Hepatocytes, Humans, Male, Middle Aged, Nevirapine, Organic Anion Transporters, Organic Anion Transporters, Sodium-Dependent, Oxazines, Rats, Ritonavir, Saquinavir, Symporters, Taurocholic Acid
Added March 5, 2014
2 Communities
2 Members
2 Resources
27 MeSH Terms
Development and characterization of LLC-PK1 cells containing Sprague-Dawley rat Abcb1a (Mdr1a): comparison of rat P-glycoprotein transport to human and mouse.
Booth-Genthe CL, Louie SW, Carlini EJ, Li B, Leake BF, Eisenhandler R, Hochman JH, Mei Q, Kim RB, Rushmore TH, Yamazaki M
(2006) J Pharmacol Toxicol Methods 54: 78-89
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, ATP Binding Cassette Transporter, Subfamily B, Member 1, ATP-Binding Cassette Transporters, Amino Acid Sequence, Animals, Cloning, Molecular, Humans, LLC-PK1 Cells, Mice, Molecular Sequence Data, Protein Transport, Rats, Rats, Sprague-Dawley, Species Specificity
Added March 27, 2014
1 Communities
1 Members
2 Resources
14 MeSH Terms