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Results: 171 to 174 of 174

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The 1988 National Maternal and Infant Health Survey: design, content, and data availability.
Sanderson M, Placek PJ, Keppel KG
(1991) Birth 18: 26-32
MeSH Terms: Data Collection, Databases, Factual, Female, Health Surveys, Humans, National Center for Health Statistics, U.S., Pregnancy, Pregnancy Outcome, Research, Research Design, Surveys and Questionnaires, United States
Show Abstract · Added March 11, 2014
The 1988 National Maternal and Infant Health Survey was conducted by the National Center for Health Statistics to study factors related to poor pregnancy outcome, such as adequacy of prenatal care; inadequate and excessive weight gain during pregnancy; maternal smoking, drinking, and drug use; and pregnancy and delivery complications. The survey is a nationally representative sample of 11,000 women who had live births, 4000 who had late fetal deaths, and 6000 who had infant deaths in 1988. Mothers were mailed questionnaires based on information from certificates of live birth, reports of fetal death, and certificates of infant death. Information supplied by the mother, prenatal care providers, and hospitals of delivery was linked with the vital records to expand knowledge of maternal and infant health in the United States. Data collection from the Longitudinal Followup of mothers in the survey began in January 1991. It provides information on health and development of low- and very low-birthweight babies, child care and safety, maternal health, maternal depression, and plans for adoption and foster care. Both surveys will provide useful data for clinicians in maternal and child health.
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1 Members
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12 MeSH Terms
A pharmacodynamic interaction between caffeine and phenylpropanolamine.
Brown NJ, Ryder D, Branch RA
(1991) Clin Pharmacol Ther 50: 363-71
MeSH Terms: Adult, Analysis of Variance, Blood Pressure, Caffeine, Catecholamines, Dose-Response Relationship, Drug, Double-Blind Method, Drug Interactions, Female, Heart Rate, Humans, Male, Natriuresis, Phenylpropanolamine, Random Allocation, Reference Values, Renin-Angiotensin System, Research Design, Time Factors
Show Abstract · Added December 10, 2013
The pharmacokinetic and pharmacodynamic interaction between caffeine and phenylpropanolamine has been investigated in six normal subjects in a double-blind, placebo-controlled, Latin-square design study. After 3 days on a 100 mEq sodium, xanthine-free diet, fasting subjects were placed in a supine position and were given 25 mg phenylpropanolamine and placebo, 250 mg caffeine and placebo, or 25 mg phenylpropanolamine and 250 mg caffeine in random order. Blood pressure, pulse, plasma renin activity, and plasma catecholamine levels were measured before and for 3 hours after drug administration. Plasma and urinary phenylpropanolamine, caffeine, and caffeine metabolite levels were measured serially for 48 hours. Coadministration of caffeine and phenylpropanolamine produced an additive increase in blood pressure. This effect could not be explained by any pharmacokinetic interaction between the two drugs and occurred even though phenylpropanolamine attenuated the epinephrine and renin response to caffeine. These data suggest that a clinically relevant interaction between caffeine and phenylpropanolamine does occur in drug-free subjects and that this interaction cannot be explained by a mechanism involving the sympathetic or renin-angiotensin systems.
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19 MeSH Terms
Adaptation in patients with chronic rheumatoid arthritis: application of a general model.
Smith CA, Wallston KA
(1992) Health Psychol 11: 151-62
MeSH Terms: Adaptation, Psychological, Adult, Arthritis, Rheumatoid, Chronic Disease, Depressive Disorder, Female, Health Status, Humans, Male, Middle Aged, Models, Theoretical, Pain, Research Design, Surveys and Questionnaires
Show Abstract · Added July 28, 2015
We derived a model of appraisal, coping, and adaptation in patients with rheumatoid arthritis (RA) from the more general theory of Lazarus and Folkman (1984) and examined this model using a longitudinal data set spanning 4 years and involving 239 RA patients (of whom 157 contributed to the primary analyses, with the remainder contributing to various follow-up analyses). This model attempted to identify the short- and long-term adaptational consequences of coping as well as the antecedents (appraisals, beliefs, social support, disease activity, etc.) that promote particular coping styles. Interrelations among the variables were examined using path-analytic techniques. Many observed relations were consistent with the model. Significant relations were subjected to more stringent analyses examining the ability of hypothesized causal variables to predict changes in outcome variables 1 year later. These analyses provided additional support for many observed relations and suggested the existence of a vicious cycle involving helplessness appraisals, passive coping with pain, and psychosocial impairment that promotes maladaptation in the face of RA. Theoretical implications, strengths, and limitations of the study are discussed.
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1 Members
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14 MeSH Terms
Making causal inferences from observational data.
Dupont WD
(1978) Biometrics 34: 713-4
MeSH Terms: Environment, Epidemiologic Methods, Humans, Lung Neoplasms, Research Design, Smoking, Statistics as Topic
Added March 21, 2014
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7 MeSH Terms