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Chloroquine affects biosynthesis of Ia molecules by inhibiting dissociation of invariant (gamma) chains from alpha-beta dimers in B cells.
Nowell J, Quaranta V
(1985) J Exp Med 162: 1371-6
MeSH Terms: B-Lymphocytes, Cell Line, Chloroquine, Histocompatibility Antigens Class II, Humans, Immunoglobulin Heavy Chains, Immunoglobulin gamma-Chains
Added March 27, 2014
1 Communities
1 Members
0 Resources
7 MeSH Terms
The human invariant chain is the core protein of the human class II-associated proteoglycan.
Giacoletto KS, Sant AJ, Bono C, Gorka J, O'Sullivan DM, Quaranta V, Schwartz BD
(1986) J Exp Med 164: 1422-39
MeSH Terms: Antigens, Differentiation, B-Lymphocyte, Chondroitin Sulfate Proteoglycans, Chondroitinases and Chondroitin Lyases, Chromobox Protein Homolog 5, Electrophoresis, Polyacrylamide Gel, Histocompatibility Antigens Class II, Humans, Methionine, Molecular Weight, Proteoglycans, Solubility
Added March 27, 2014
1 Communities
1 Members
0 Resources
11 MeSH Terms
Structure of the human Ia-associated invariant (gamma)-chain gene: identification of 5' sequences shared with major histocompatibility complex class II genes.
O'Sullivan DM, Larhammar D, Wilson MC, Peterson PA, Quaranta V
(1986) Proc Natl Acad Sci U S A 83: 4484-8
MeSH Terms: Base Sequence, Chromosome Mapping, Cloning, Molecular, Gene Expression Regulation, Genes, HLA-DR Antigens, Histocompatibility Antigens Class II, Humans, Macromolecular Substances, Promoter Regions, Genetic, Sequence Homology, Nucleic Acid
Added March 27, 2014
1 Communities
1 Members
0 Resources
11 MeSH Terms
Acute tubulointerstitial nephritis associated with aminonucleoside nephrosis.
Eddy AA, Michael AF
(1988) Kidney Int 33: 14-23
MeSH Terms: Albuminuria, Animals, Female, Histocompatibility Antigens Class II, Immunohistochemistry, Leukocytes, Mononuclear, Nephritis, Interstitial, Nephrosis, Lipoid, Puromycin, Puromycin Aminonucleoside, Rats, Rats, Inbred Lew
Added February 3, 2012
0 Communities
1 Members
0 Resources
12 MeSH Terms
Immunoregulation by T cells. I. Characterization of the IEk-specific Lbd self-reactive T cell clone that helps, suppresses and contrasupresses B cell responses.
Quintáns J, Suzuki H, Sosman JA, Shah PD
(1986) J Immunol 136: 1974-81
MeSH Terms: Animals, Antibodies, Monoclonal, Antibody Formation, Antigens, Differentiation, T-Lymphocyte, Antigens, Ly, Antigens, Surface, B-Lymphocytes, Clone Cells, Histocompatibility Antigens, Histocompatibility Antigens Class II, Immune Tolerance, Immunologic Memory, Lymphocyte Activation, Major Histocompatibility Complex, Mice, Mice, Inbred Strains, T-Lymphocytes, T-Lymphocytes, Helper-Inducer, T-Lymphocytes, Regulatory
Added March 5, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Antigen-specific recognition of autologous leukemia cells and allogeneic class-I MHC antigens by IL-2-activated cytotoxic T cells from a patient with acute T-cell leukemia.
Fisch P, Weil-Hillman G, Uppenkamp M, Hank JA, Chen BP, Sosman JA, Bridges A, Colamonici OR, Sondel PM
(1989) Blood 74: 343-53
MeSH Terms: Adult, Antibodies, Monoclonal, Antigens, Differentiation, T-Lymphocyte, Antigens, Neoplasm, CD3 Complex, Cytotoxicity, Immunologic, Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor, Histocompatibility Antigens Class I, Humans, Immunity, Cellular, Immunologic Techniques, In Vitro Techniques, Interleukin-2, Killer Cells, Natural, Leukemia-Lymphoma, Adult T-Cell, Lymphocyte Activation, Male, Receptors, Antigen, T-Cell, Receptors, Antigen, T-Cell, gamma-delta, T-Lymphocytes, Cytotoxic, Tumor Cells, Cultured
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Transgenic HLA-DR alpha faithfully reconstitutes IE-controlled immune functions and induces cross-tolerance to E alpha in E alpha 0 mutant mice.
Lawrance SK, Karlsson L, Price J, Quaranta V, Ron Y, Sprent J, Peterson PA
(1989) Cell 58: 583-94
MeSH Terms: Animals, Genes, Genetic Complementation Test, HLA-DR Antigens, Histocompatibility Antigens Class II, Humans, Immunity, Cellular, Lymphocyte Culture Test, Mixed, Macromolecular Substances, Mice, Mice, Transgenic, Protein Binding, Receptors, Antigen, T-Cell, Structure-Activity Relationship, T-Lymphocytes, Tissue Distribution
Added March 27, 2014
1 Communities
1 Members
0 Resources
16 MeSH Terms
A lipopolysaccharide-induced DNA-binding protein for a class II gene in B cells is distinct from NF-kappa B.
Gravallese EM, Boothby MR, Smas CM, Glimcher LH
(1989) Mol Cell Biol 9: 3184-92
MeSH Terms: Animals, B-Lymphocytes, Base Sequence, Cell Nucleus, DNA, DNA-Binding Proteins, Deoxyribonuclease I, Histocompatibility Antigens Class II, Lipopolysaccharides, Mice, Mice, Nude, Molecular Sequence Data, NF-kappa B, RNA, Spleen, Transcription Factors
Added December 10, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
Cyclosporine-induced autoimmunity in rats carrying thymus allografts.
Babcock SK, Niswender K, Wilson DB, Bellgrau D
(1990) Transplantation 50: 278-81
MeSH Terms: Animals, Antigens, Differentiation, B-Lymphocyte, Antigens, Differentiation, T-Lymphocyte, Autoimmune Diseases, Cyclosporins, Histocompatibility Antigens Class II, Lymphocyte Activation, Lymphocytes, Rats, Rats, Inbred Strains, Thymus Gland
Added February 15, 2016
0 Communities
1 Members
0 Resources
11 MeSH Terms
Recognition of the product of a novel MHC TL region gene (27b) by a mouse gamma delta T cell receptor.
Ito K, Van Kaer L, Bonneville M, Hsu S, Murphy DB, Tonegawa S
(1990) Cell 62: 549-61
MeSH Terms: Amino Acid Sequence, Animals, Base Sequence, DNA Probes, Exons, Genes, MHC Class I, Histocompatibility Antigens Class I, Introns, Lymphocyte Activation, Lymphocytes, Mice, Mice, Inbred BALB C, Mice, Inbred Strains, Molecular Sequence Data, RNA Splicing, Receptors, Antigen, T-Cell, T-Lymphocytes, Transfection
Added December 10, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms