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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 131 to 137 of 137

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Clinical research subject recruitment: the Volunteer for Vanderbilt Research Program www.volunteer.mc.vanderbilt.edu.
Harris PA, Lane L, Biaggioni I
(2005) J Am Med Inform Assoc 12: 608-13
MeSH Terms: Biomedical Research, Clinical Trials as Topic, Consumer Behavior, Data Collection, Ethics Committees, Research, Human Experimentation, Internet, Patient Selection, Registries, Software, Tennessee
Show Abstract · Added December 10, 2013
This article provides information concerning a novel research subject recruitment registry developed at Vanderbilt University. Project goals were (1) to provide a mechanism for lay individuals to self-enter information conveying interest in volunteering for clinical research and (2) provide tools for researchers to select and contact potential volunteers based on study-specific inclusion criteria. The registry was built and offered as an institutional resource to all university scientists conducting institutional review board-approved research. The authors present (1) a model for redesigning workflow associated with subject registration, volunteer retrieval, and subject contact; (2) details of a Web-based software application used as a focal point in designing workflow for our system; (3) descriptive statistics for volunteer and researcher use of the system during the first 32 months of operation; (4) cost estimates for the project; and (5) a set of recommendations for other medical centers wishing to adopt similar methodology.
0 Communities
2 Members
0 Resources
11 MeSH Terms
Gene expression microarray studies in polygenic psychiatric disorders: applications and data analysis.
Konradi C
(2005) Brain Res Brain Res Rev 50: 142-55
MeSH Terms: Biomedical Research, Databases, Genetic, Gene Expression Profiling, Humans, Mental Disorders, Microarray Analysis, RNA, Messenger, Reverse Transcriptase Polymerase Chain Reaction, Statistics as Topic
Show Abstract · Added May 27, 2014
Gene expression microarrays have become a mainstream technology that can provide valuable insight into psychiatric disorders. Gene expression studies in post mortem brain samples of schizophrenia and bipolar disorder have the potential to yield novel clues about the pathophysiology of these complex trait disorders. In the present review, a short introduction of the genetic and molecular background of schizophrenia and bipolar disorder is followed by a discussion of the basic concept and limits of gene expression microarray technology, and the complexities surrounding the analysis of thousands of gene transcripts. Although this review is intended for use in most platforms, it has a particular focus on the commercially available Affymetrix system. Various computer programs and their principal features are discussed, and it is shown how these programs can be applied to reveal a biological context of microarray findings. I will demonstrate how the programs can help to judge the results rather than focus on their statistical principles. The strength of gene array experiments is their emphasis on broad, biological themes, rather than on specific genes, and proper biostatistical approaches are important to ensure reproducibility of the findings. All results should be verified by independent means. This review is intended to help brain researchers who want to apply gene expression microarray technology to conceptualize research strategies and sample analysis.
0 Communities
1 Members
0 Resources
9 MeSH Terms
The desire to do something good.
Siegel V
(2004) Biotechniques 37: 17
MeSH Terms: Biochemistry, Biomedical Research, History, 21st Century, Mathematics, United States
Added December 1, 2015
0 Communities
1 Members
0 Resources
5 MeSH Terms
A quantitative analysis of qualitative studies in clinical journals for the 2000 publishing year.
McKibbon KA, Gadd CS
(2004) BMC Med Inform Decis Mak 4: 11
MeSH Terms: Bibliometrics, Biomedical Research, Health Services Research, Humans, Nursing Research, Periodicals as Topic, Qualitative Research, Research Design
Show Abstract · Added January 20, 2015
BACKGROUND - Quantitative studies are becoming more recognized as important to understanding health care with all of its richness and complexities. The purpose of this descriptive survey was to provide a quantitative evaluation of the qualitative studies published in 170 core clinical journals for 2000.
METHODS - All identified studies that used qualitative methods were reviewed to ascertain which clinical journals publish qualitative studies and to extract research methods, content (persons and health care issues studied), and whether mixed methods (quantitative and qualitative methods) were used.
RESULTS - 60 330 articles were reviewed. 355 reports of original qualitative studies and 12 systematic review articles were identified in 48 journals. Most of the journals were in the discipline of nursing. Only 4 of the most highly cited health care journals, based on ISI Science Citation Index (SCI) Impact Factors, published qualitative studies. 37 of the 355 original reports used both qualitative and quantitative (mixed) methods. Patients and non-health care settings were the most common groups of people studied. Diseases and conditions were cancer, mental health, pregnancy and childbirth, and cerebrovascular disease with many other diseases and conditions represented. Phenomenology and grounded theory were commonly used; substantial ethnography was also present. No substantial differences were noted for content or methods when articles published in all disciplines were compared with articles published in nursing titles or when studies with mixed methods were compared with studies that included only qualitative methods.
CONCLUSIONS - The clinical literature includes many qualitative studies although they are often published in nursing journals or journals with low SCI Impact Factor journals. Many qualitative studies incorporate both qualitative and quantitative methods.
0 Communities
1 Members
0 Resources
8 MeSH Terms
Mentoring clinical trials in thoracic and cardiovascular surgery: a new role for the Society of Thoracic Surgeons.
Gaissert HA, Casale AS, Creswell LL, Ferguson TB, Fullerton DA, Kernstine KH, McMullan DM, Ring WS, Putnam JB, Society of Thoracic Surgeons Workforce on Clinical Trials
(2004) Ann Thorac Surg 77: 1874-5
MeSH Terms: Biomedical Research, Clinical Trials as Topic, Mentors, Physician's Role, Societies, Medical, Thoracic Surgery
Added March 27, 2014
0 Communities
1 Members
0 Resources
6 MeSH Terms
The rise of litigation in human subjects research.
Murff H
(2004) Ann Intern Med 140: 670
MeSH Terms: Biomedical Research, Humans, Research Subjects, Risk Management, United States
Added March 5, 2014
0 Communities
1 Members
0 Resources
5 MeSH Terms
PLoS biology--we're open.
Bernstein P, Cohen B, MacCallum C, Parthasarathy H, Patterson M, Siegel V
(2003) PLoS Biol 1: E34
MeSH Terms: Access to Information, Biomedical Research, Information Dissemination, Information Storage and Retrieval, Internet, Periodicals as Topic, Publishing
Added December 1, 2015
0 Communities
1 Members
0 Resources
7 MeSH Terms