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Safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis.
Bernard GR, Macias WL, Joyce DE, Williams MD, Bailey J, Vincent JL
(2003) Crit Care 7: 155-63
MeSH Terms: Adult, Anti-Infective Agents, Consumer Product Safety, Hemorrhage, Humans, Intracranial Hemorrhages, Protein C, Recombinant Proteins, Sepsis
Added March 5, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Clinical trial of interactive and videotaped educational interventions reduce infection, reactive depression, and rehospitalizations for sepsis in patients on home parenteral nutrition.
Smith CE, Curtas S, Kleinbeck SV, Werkowitch M, Mosier M, Seidner DL, Steiger E
(2003) JPEN J Parenter Enteral Nutr 27: 137-45
MeSH Terms: Adolescent, Adult, Catheters, Indwelling, Depression, Equipment Contamination, Female, Hospitalization, Humans, Infection Control, Male, Middle Aged, Parenteral Nutrition, Home, Patient Education as Topic, Problem Solving, Quality of Life, Sepsis, Treatment Outcome, Videotape Recording
Added September 30, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
Abnormal heart rate characteristics preceding neonatal sepsis and sepsis-like illness.
Griffin MP, O'Shea TM, Bissonette EA, Harrell FE, Lake DE, Moorman JR
(2003) Pediatr Res 53: 920-6
MeSH Terms: Heart Rate, Humans, Infant, Newborn, Infant, Newborn, Diseases, Prospective Studies, Sepsis
Added February 28, 2014
0 Communities
1 Members
0 Resources
6 MeSH Terms
Beta 2 microglobulin knockout mice are resistant to lethal intraabdominal sepsis.
Sherwood ER, Lin CY, Tao W, Hartmann CA, Dujon JE, French AJ, Varma TK
(2003) Am J Respir Crit Care Med 167: 1641-9
MeSH Terms: Adoptive Transfer, Animals, CD8-Positive T-Lymphocytes, Cecum, Disease Models, Animal, Female, G(M1) Ganglioside, Immunity, Innate, Inflammation, Killer Cells, Natural, Ligation, Lymphopenia, Mice, Mice, Inbred C57BL, Mice, Knockout, Peritonitis, Sepsis, Survival Analysis, beta 2-Microglobulin
Added October 18, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis.
Ely EW, Laterre PF, Angus DC, Helterbrand JD, Levy H, Dhainaut JF, Vincent JL, Macias WL, Bernard GR, PROWESS Investigators
(2003) Crit Care Med 31: 12-9
MeSH Terms: APACHE, Adult, Aged, Analysis of Variance, Anti-Infective Agents, Double-Blind Method, Female, Hemorrhage, Humans, Logistic Models, Male, Middle Aged, Multivariate Analysis, Protein C, Recombinant Proteins, Risk Factors, Sepsis, Survival Rate
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Drotrecogin alfa (activated) (recombinant human activated protein C) for the treatment of severe sepsis.
Bernard GR
(2003) Crit Care Med 31: S85-93
MeSH Terms: Animals, Anti-Infective Agents, Clinical Trials, Phase II as Topic, Clinical Trials, Phase III as Topic, Disease Models, Animal, Drug Approval, Humans, Protein C, Rats, Recombinant Proteins, Sepsis, Severity of Illness Index, Survival Rate
Added March 5, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Bioartificial kidney alters cytokine response and hemodynamics in endotoxin-challenged uremic animals.
Fissell WH, Dyke DB, Weitzel WF, Buffington DA, Westover AJ, MacKay SM, Gutierrez JM, Humes HD
(2002) Blood Purif 20: 55-60
MeSH Terms: Acute Kidney Injury, Adjuvants, Immunologic, Animals, Blood Pressure, Cytokines, Disease Models, Animal, Dogs, Endotoxins, Hemodynamics, Humans, Interleukin-10, Kidneys, Artificial, Multiple Organ Failure, Renal Replacement Therapy, Sepsis, Uremia
Added August 21, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
Safety and dose relationship of recombinant human activated protein C for coagulopathy in severe sepsis.
Bernard GR, Ely EW, Wright TJ, Fraiz J, Stasek JE, Russell JA, Mayers I, Rosenfeld BA, Morris PE, Yan SB, Helterbrand JD
(2001) Crit Care Med 29: 2051-9
MeSH Terms: Critical Care, Disseminated Intravascular Coagulation, Dose-Response Relationship, Drug, Double-Blind Method, Drug Administration Schedule, Female, Fibrin Fibrinogen Degradation Products, Hospital Mortality, Humans, Infusions, Intravenous, Male, Middle Aged, Protein C, Recombinant Proteins, Sepsis, Severity of Illness Index
Added March 5, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Airway and lung in sepsis.
Martin GS, Bernard GR, International Sepsis Forum
(2001) Intensive Care Med 27 Suppl 1: S63-79
MeSH Terms: Humans, Prognosis, Pulmonary Alveoli, Respiration, Artificial, Respiratory Distress Syndrome, Respiratory Mechanics, Sepsis
Added March 5, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
Pilot study assessing TNF gene polymorphism as a prognostic marker for disease progression in neonates with sepsis.
Weitkamp JH, Stüber F, Bartmann P
(2000) Infection 28: 92-6
MeSH Terms: Adult, Biomarkers, Critical Care, Deoxyribonucleases, Type II Site-Specific, Disease Progression, Female, Genotype, Humans, Infant, Newborn, Infant, Very Low Birth Weight, Lymphotoxin-alpha, Male, Pilot Projects, Polymorphism, Genetic, Prognosis, Sepsis, Tumor Necrosis Factor-alpha
Added February 27, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms