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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 40

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ErbB3 drives mammary epithelial survival and differentiation during pregnancy and lactation.
Williams MM, Vaught DB, Joly MM, Hicks DJ, Sanchez V, Owens P, Rahman B, Elion DL, Balko JM, Cook RS
(2017) Breast Cancer Res 19: 105
MeSH Terms: Alleles, Animals, Breast, Cell Differentiation, Cell Proliferation, Cell Survival, Epithelial Cells, Female, Gene Knockout Techniques, Immunohistochemistry, Lactation, Mice, Mice, Transgenic, Phosphatidylinositol 3-Kinases, Pregnancy, Proto-Oncogene Proteins c-akt, RNA, Messenger, Receptor, ErbB-3, Receptor, ErbB-4, STAT5 Transcription Factor, Signal Transduction
Added March 14, 2018
0 Communities
2 Members
0 Resources
21 MeSH Terms
The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1.
Almohazey D, Lo YH, Vossler CV, Simmons AJ, Hsieh JJ, Bucar EB, Schumacher MA, Hamilton KE, Lau KS, Shroyer NF, Frey MR
(2017) Cell Death Differ 24: 855-865
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Communication, Cell Count, Cell Differentiation, Extracellular Signal-Regulated MAP Kinases, Female, Gene Expression Regulation, HT29 Cells, Humans, Ileum, MAP Kinase Signaling System, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Paneth Cells, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Receptor, ErbB-3, Receptors, G-Protein-Coupled, Stem Cell Niche, Stem Cells
Added October 16, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Integrated genomic and molecular characterization of cervical cancer.
Cancer Genome Atlas Research Network, Albert Einstein College of Medicine, Analytical Biological Services, Barretos Cancer Hospital, Baylor College of Medicine, Beckman Research Institute of City of Hope, Buck Institute for Research on Aging, Canada's Michael Smith Genome Sciences Centre, Harvard Medical School, Helen F. Graham Cancer Center &Research Institute at Christiana Care Health Services, HudsonAlpha Institute for Biotechnology, ILSbio, LLC, Indiana University School of Medicine, Institute of Human Virology, Institute for Systems Biology, International Genomics Consortium, Leidos Biomedical, Massachusetts General Hospital, McDonnell Genome Institute at Washington University, Medical College of Wisconsin, Medical University of South Carolina, Memorial Sloan Kettering Cancer Center, Montefiore Medical Center, NantOmics, National Cancer Institute, National Hospital, Abuja, Nigeria, National Human Genome Research Institute, National Institute of Environmental Health Sciences, National Institute on Deafness &Other Communication Disorders, Ontario Tumour Bank, London Health Sciences Centre, Ontario Tumour Bank, Ontario Institute for Cancer Research, Ontario Tumour Bank, The Ottawa Hospital, Oregon Health &Science University, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, SRA International, St Joseph's Candler Health System, Eli &Edythe L. Broad Institute of Massachusetts Institute of Technology &Harvard University, Research Institute at Nationwide Children's Hospital, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, University of Bergen, University of Texas MD Anderson Cancer Center, University of Abuja Teaching Hospital, University of Alabama at Birmingham, University of California, Irvine, University of California Santa Cruz, University of Kansas Medical Center, University of Lausanne, University of New Mexico Health Sciences Center, University of North Carolina at Chapel Hill, University of Oklahoma Health Sciences Center, University of Pittsburgh, University of São Paulo, Ribeir ão Preto Medical School, University of Southern California, University of Washington, University of Wisconsin School of Medicine &Public Health, Van Andel Research Institute, Washington University in St Louis
(2017) Nature 543: 378-384
MeSH Terms: APOBEC-1 Deaminase, Adenocarcinoma, B7-H1 Antigen, Carcinoma, Squamous Cell, Caspase 8, DNA-Binding Proteins, Female, Genomics, HLA-A Antigens, Human papillomavirus 16, Humans, Keratins, Mitogen-Activated Protein Kinase Kinases, Molecular Targeted Therapy, Mutation, Nuclear Proteins, PTEN Phosphohydrolase, Phosphatidylinositol 3-Kinases, Programmed Cell Death 1 Ligand 2 Protein, Protein-Serine-Threonine Kinases, Proteomics, Proto-Oncogene Proteins p21(ras), RNA, Long Noncoding, Receptor, ErbB-3, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, Transcription Factors, Uterine Cervical Neoplasms, Virus Integration
Added October 30, 2019
0 Communities
1 Members
0 Resources
30 MeSH Terms
Loss of hepatocyte ERBB3 but not EGFR impairs hepatocarcinogenesis.
Scheving LA, Zhang X, Stevenson MC, Weintraub MA, Abbasi A, Clarke AM, Threadgill DW, Russell WE
(2015) Am J Physiol Gastrointest Liver Physiol 309: G942-54
MeSH Terms: Age Factors, Animals, Cell Proliferation, Cell Transformation, Neoplastic, Diethylnitrosamine, ErbB Receptors, Genotype, Hepatocytes, Liver Neoplasms, Liver Regeneration, Male, Mice, 129 Strain, Mice, Inbred C3H, Mice, Knockout, Phenotype, Phosphorylation, Receptor, ErbB-3, STAT3 Transcription Factor, Signal Transduction
Added May 5, 2016
0 Communities
1 Members
0 Resources
19 MeSH Terms
Decreased LRIG1 in fulvestrant-treated luminal breast cancer cells permits ErbB3 upregulation and increased growth.
Morrison MM, Williams MM, Vaught DB, Hicks D, Lim J, McKernan C, Aurisicchio L, Ciliberto G, Simion C, Sweeney C, Cook RS
(2016) Oncogene 35: 1143-52
MeSH Terms: Animals, Breast Neoplasms, Cell Proliferation, Disease-Free Survival, Drug Resistance, Neoplasm, Estradiol, Estrogen Receptor alpha, Estrogens, Female, Fulvestrant, Gene Expression Regulation, Neoplastic, Humans, MCF-7 Cells, Membrane Glycoproteins, Mice, Receptor, ErbB-3, Xenograft Model Antitumor Assays
Added April 15, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Loss of hepatocyte EGFR has no effect alone but exacerbates carbon tetrachloride-induced liver injury and impairs regeneration in hepatocyte Met-deficient mice.
Scheving LA, Zhang X, Stevenson MC, Threadgill DW, Russell WE
(2015) Am J Physiol Gastrointest Liver Physiol 308: G364-77
MeSH Terms: Animals, Carbon Tetrachloride, Chemical and Drug Induced Liver Injury, Cyclin A, Cyclin D1, Epidermal Growth Factor, ErbB Receptors, Hepatocytes, Liver Regeneration, Mice, Neuregulin-1, Proto-Oncogene Proteins c-met, Receptor, ErbB-3
Added May 5, 2016
0 Communities
1 Members
0 Resources
13 MeSH Terms
ERBB receptors: from oncogene discovery to basic science to mechanism-based cancer therapeutics.
Arteaga CL, Engelman JA
(2014) Cancer Cell 25: 282-303
MeSH Terms: Animals, Antibodies, Monoclonal, Humanized, Drug Resistance, Neoplasm, ErbB Receptors, Humans, Mice, Neoplasms, Receptor, ErbB-2, Receptor, ErbB-3, Receptor, ErbB-4, Signal Transduction
Added April 1, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Neuregulin-1β induces embryonic stem cell cardiomyogenesis via ErbB3/ErbB2 receptors.
Hao J, Galindo CL, Tran TL, Sawyer DB
(2014) Biochem J 458: 335-41
MeSH Terms: Animals, Cell Differentiation, Cell Line, Cyclic AMP Response Element-Binding Protein, Embryonic Stem Cells, Gene Knockdown Techniques, Mice, Myocytes, Cardiac, Nerve Tissue Proteins, Neuregulin-1, RNA, Small Interfering, Receptor, ErbB-2, Receptor, ErbB-3, Signal Transduction
Added May 21, 2014
1 Communities
1 Members
0 Resources
14 MeSH Terms
ErbB3 downregulation enhances luminal breast tumor response to antiestrogens.
Morrison MM, Hutchinson K, Williams MM, Stanford JC, Balko JM, Young C, Kuba MG, Sánchez V, Williams AJ, Hicks DJ, Arteaga CL, Prat A, Perou CM, Earp HS, Massarweh S, Cook RS
(2013) J Clin Invest 123: 4329-43
MeSH Terms: Animals, Antibodies, Monoclonal, Antineoplastic Agents, Hormonal, Breast Neoplasms, Cell Proliferation, Cell Survival, Down-Regulation, Drug Resistance, Neoplasm, Drug Synergism, ErbB Receptors, Estradiol, Estrogen Receptor Modulators, Female, Fulvestrant, Gene Dosage, Gene Expression, Gene Expression Regulation, Neoplastic, Humans, MCF-7 Cells, Mice, Mice, Inbred BALB C, Mice, Nude, Oligonucleotide Array Sequence Analysis, Receptor, ErbB-2, Receptor, ErbB-3, Signal Transduction, Survival Analysis, Transcriptome, Xenograft Model Antitumor Assays
Added March 7, 2014
1 Communities
3 Members
0 Resources
29 MeSH Terms
Mapping C-terminal transactivation domains of the nuclear HER family receptor tyrosine kinase HER3.
Brand TM, Iida M, Luthar N, Wleklinski MJ, Starr MM, Wheeler DL
(2013) PLoS One 8: e71518
MeSH Terms: Cell Line, Cell Nucleus, Cyclin D1, Humans, Mutation, Promoter Regions, Genetic, Protein Structure, Tertiary, Receptor, ErbB-3, Transcriptional Activation
Added June 22, 2015
0 Communities
1 Members
0 Resources
9 MeSH Terms