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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 61

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Interleukin-22 drives nitric oxide-dependent DNA damage and dysplasia in a murine model of colitis-associated cancer.
Wang C, Gong G, Sheh A, Muthupalani S, Bryant EM, Puglisi DA, Holcombe H, Conaway EA, Parry NAP, Bakthavatchalu V, Short SP, Williams CS, Wogan GN, Tannenbaum SR, Fox JG, Horwitz BH
(2017) Mucosal Immunol 10: 1504-1517
MeSH Terms: Animals, Antibodies, Blocking, Colitis, Ulcerative, Colon, Colonic Neoplasms, DNA Breaks, Double-Stranded, DNA-Binding Proteins, Disease Models, Animal, Helicobacter Infections, Helicobacter hepaticus, Humans, Inflammation, Interleukins, Macrophages, Peritoneal, Mice, Mice, 129 Strain, Mice, Knockout, Neoplasms, Nitric Oxide, Nitric Oxide Synthase Type II
Added April 15, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Imbalance between HDAC and HAT activities drives aberrant STAT1/MyD88 expression in macrophages from type 1 diabetic mice.
Filgueiras LR, Brandt SL, Ramalho TR, Jancar S, Serezani CH
(2017) J Diabetes Complications 31: 334-339
MeSH Terms: Acetylation, Animals, Bone Marrow Cells, Cells, Cultured, Diabetes Mellitus, Type 1, Enzyme Inhibitors, Epigenesis, Genetic, Gene Expression Regulation, Glucose, Histone Acetyltransferases, Histone Deacetylases, Histones, Macrophages, Macrophages, Peritoneal, Male, Mice, Inbred C57BL, Myeloid Differentiation Factor 88, Osmolar Concentration, Promoter Regions, Genetic, Protein Processing, Post-Translational, STAT1 Transcription Factor, Streptozocin
Added May 4, 2017
0 Communities
1 Members
0 Resources
22 MeSH Terms
Activation of Epidermal Growth Factor Receptor in Macrophages Mediates Feedback Inhibition of M2 Polarization and Gastrointestinal Tumor Cell Growth.
Zhao G, Liu L, Peek RM, Hao X, Polk DB, Li H, Yan F
(2016) J Biol Chem 291: 20462-72
MeSH Terms: Animals, Cell Line, Tumor, ErbB Receptors, Gastrointestinal Neoplasms, Gene Expression Regulation, Neoplastic, Heparin-binding EGF-like Growth Factor, Humans, Interleukin-4, Macrophages, Peritoneal, Mice, Mice, Knockout, RAW 264.7 Cells, Transcriptional Activation
Added April 6, 2017
0 Communities
1 Members
0 Resources
13 MeSH Terms
Opposing roles of LTB4 and PGE2 in regulating the inflammasome-dependent scorpion venom-induced mortality.
Zoccal KF, Sorgi CA, Hori JI, Paula-Silva FW, Arantes EC, Serezani CH, Zamboni DS, Faccioli LH
(2016) Nat Commun 7: 10760
MeSH Terms: Animals, Arachidonate 5-Lipoxygenase, Blotting, Western, Carrier Proteins, Celecoxib, Cyclic AMP, Cyclic AMP-Dependent Protein Kinases, Cyclooxygenase Inhibitors, Dinoprostone, In Vitro Techniques, Indoles, Indomethacin, Inflammasomes, Interleukin-1beta, Leukotriene B4, Lipoxygenase Inhibitors, Macrophages, Macrophages, Peritoneal, Mice, Mice, Knockout, NF-kappa B, NLR Family, Pyrin Domain-Containing 3 Protein, Phosphoproteins, Prostaglandin Antagonists, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Prostaglandin E, EP4 Subtype, Reverse Transcriptase Polymerase Chain Reaction, Scorpion Stings, Scorpion Venoms, Scorpions, Xanthones
Added May 4, 2017
0 Communities
1 Members
0 Resources
31 MeSH Terms
Macrophage IKKα Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival, and Decreases Early Atherosclerosis.
Babaev VR, Ding L, Zhang Y, May JM, Lin PC, Fazio S, Linton MF
(2016) Arterioscler Thromb Vasc Biol 36: 598-607
MeSH Terms: Animals, Apoptosis, Atherosclerosis, Cell Survival, Cells, Cultured, Diet, Western, Disease Models, Animal, Female, I-kappa B Kinase, Inflammation Mediators, Liver, Liver Transplantation, Macrophages, Peritoneal, Male, Mechanistic Target of Rapamycin Complex 2, Mice, Inbred C57BL, Mice, Knockout, Multiprotein Complexes, Phosphorylation, Protein Kinase Inhibitors, Proto-Oncogene Proteins c-akt, Receptors, LDL, Signal Transduction, TOR Serine-Threonine Kinases, Time Factors
Added February 22, 2016
0 Communities
2 Members
0 Resources
25 MeSH Terms
The homing receptor CD44 is involved in the progression of precancerous gastric lesions in patients infected with Helicobacter pylori and in development of mucous metaplasia in mice.
Garay J, Piazuelo MB, Majumdar S, Li L, Trillo-Tinoco J, Del Valle L, Schneider BG, Delgado AG, Wilson KT, Correa P, Zabaleta J
(2016) Cancer Lett 371: 90-8
MeSH Terms: Animals, Antigens, Ly, Cells, Cultured, Chemotaxis, Leukocyte, Disease Models, Animal, Disease Progression, Female, Gastric Mucosa, Gastritis, Atrophic, Helicobacter Infections, Helicobacter pylori, Humans, Hyaluronan Receptors, Interferon-gamma, Macrophages, Peritoneal, Mice, Knockout, Neutrophil Infiltration, Neutrophils, Precancerous Conditions, Signal Transduction, Stomach Neoplasms, Time Factors
Added February 15, 2016
0 Communities
1 Members
0 Resources
22 MeSH Terms
Outer surface protein OspC is an antiphagocytic factor that protects Borrelia burgdorferi from phagocytosis by macrophages.
Carrasco SE, Troxell B, Yang Y, Brandt SL, Li H, Sandusky GE, Condon KW, Serezani CH, Yang XF
(2015) Infect Immun 83: 4848-60
MeSH Terms: Animals, Antigens, Bacterial, B-Lymphocytes, Bacterial Outer Membrane Proteins, Borrelia burgdorferi, Cell Line, Female, Gene Expression Regulation, Bacterial, Genes, Reporter, Green Fluorescent Proteins, Humans, Immune Evasion, Killer Cells, Natural, Lyme Disease, Macrophages, Peritoneal, Mice, Mice, Inbred NOD, Mice, Knockout, Mice, SCID, Neutrophils, T-Lymphocytes
Added May 4, 2017
0 Communities
1 Members
0 Resources
21 MeSH Terms
Local effects of human PCSK9 on the atherosclerotic lesion.
Giunzioni I, Tavori H, Covarrubias R, Major AS, Ding L, Zhang Y, DeVay RM, Hong L, Fan D, Predazzi IM, Rashid S, Linton MF, Fazio S
(2016) J Pathol 238: 52-62
MeSH Terms: Animals, Atherosclerosis, Disease Models, Animal, Flow Cytometry, Fluorescent Antibody Technique, Humans, Immunohistochemistry, Immunoprecipitation, Macrophages, Peritoneal, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Proprotein Convertase 9, Proprotein Convertases, Receptors, LDL, Serine Endopeptidases, Transplantation Chimera
Added February 3, 2017
1 Communities
2 Members
0 Resources
18 MeSH Terms
Hepcidin-ferroportin axis controls toll-like receptor 4 dependent macrophage inflammatory responses in human atherosclerotic plaques.
Habib A, Polavarapu R, Karmali V, Guo L, Van Dam R, Cheng Q, Akahori H, Saeed O, Nakano M, Pachura K, Hong CC, Shin E, Kolodgie F, Virmani R, Finn AV
(2015) Atherosclerosis 241: 692-700
MeSH Terms: Animals, Antigens, CD, Antigens, Differentiation, Myelomonocytic, Cation Transport Proteins, Foam Cells, Haptoglobins, Hemoglobins, Hepcidins, Humans, Inflammation, Iron, Lipopolysaccharides, Lipoproteins, LDL, Macrophages, Macrophages, Peritoneal, Male, Membrane Microdomains, Mice, Mice, Inbred C57BL, Mice, Knockout, Myeloid Differentiation Factor 88, Plaque, Atherosclerotic, Receptors, Cell Surface, Signal Transduction, Toll-Like Receptor 4, Tumor Necrosis Factor-alpha
Added July 7, 2015
1 Communities
1 Members
0 Resources
26 MeSH Terms
IκB kinase activity drives fetal lung macrophage maturation along a non-M1/M2 paradigm.
Stouch AN, Zaynagetdinov R, Barham WJ, Stinnett AM, Slaughter JC, Yull FE, Hoffman HM, Blackwell TS, Prince LS
(2014) J Immunol 193: 1184-93
MeSH Terms: Animals, Animals, Newborn, Biomarkers, Cell Differentiation, Enzyme Activation, Female, Gene Expression Regulation, Developmental, Gene Expression Regulation, Enzymologic, Humans, I-kappa B Kinase, Immunophenotyping, Inflammation, Lung Diseases, Macrophage Activation, Macrophages, Alveolar, Macrophages, Peritoneal, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic
Added December 17, 2014
1 Communities
3 Members
0 Resources
20 MeSH Terms