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Results: 1 to 10 of 50

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Cyclooxygenase-2 deficiency attenuates lipopolysaccharide-induced inflammation, apoptosis, and acute lung injury in adult mice.
Nelin LD, Jin Y, Chen B, Liu Y, Rogers LK, Reese J
(2022) Am J Physiol Regul Integr Comp Physiol 322: R126-R135
MeSH Terms: Acute Lung Injury, Animals, Apoptosis, Caspase 3, Caspase 9, Chemokine CCL2, Cyclooxygenase 2, Disease Models, Animal, Female, Interleukin-10, Lipopolysaccharides, Lung, Male, Mice, Knockout, Pneumonia, Signal Transduction, Tumor Necrosis Factor-alpha
Added February 1, 2022
0 Communities
1 Members
0 Resources
17 MeSH Terms
Successful Establishment of Primary Type II Alveolar Epithelium with 3D Organotypic Coculture.
Sucre JMS, Jetter CS, Loomans H, Williams J, Plosa EJ, Benjamin JT, Young LR, Kropski JA, Calvi CL, Kook S, Wang P, Gleaves L, Eskaros A, Goetzl L, Blackwell TS, Guttentag SH, Zijlstra A
(2018) Am J Respir Cell Mol Biol 59: 158-166
MeSH Terms: Cell Communication, Cells, Cultured, Coculture Techniques, Epithelial Cells, Fibroblasts, Humans, Lung, Lung Injury, Phenotype
Added April 1, 2019
0 Communities
3 Members
0 Resources
9 MeSH Terms
Epithelial Heparan Sulfate Contributes to Alveolar Barrier Function and Is Shed during Lung Injury.
Haeger SM, Liu X, Han X, McNeil JB, Oshima K, McMurtry SA, Yang Y, Ouyang Y, Zhang F, Nozik-Grayck E, Zemans RL, Tuder RM, Bastarache JA, Linhardt RJ, Schmidt EP
(2018) Am J Respir Cell Mol Biol 59: 363-374
MeSH Terms: Animals, Capillary Permeability, Endothelium, Vascular, Glycocalyx, Heparitin Sulfate, Lipopolysaccharides, Lung Injury, Mice, Respiratory Distress Syndrome, Syndecans
Added May 31, 2018
0 Communities
1 Members
0 Resources
10 MeSH Terms
GBT1118, a compound that increases the oxygen affinity of hemoglobin, improves survival in murine hypoxic acute lung injury.
Putz ND, Shaver CM, Dufu K, Li CM, Xu Q, Hutchaleelaha A, Lehrer-Graiwer J, Majka SM, Ware LB, Bastarache JA
(2018) J Appl Physiol (1985) 124: 899-905
MeSH Terms: Acute Lung Injury, Animals, Benzaldehydes, Disease Models, Animal, Drug Evaluation, Preclinical, Hypoxia, Lipopolysaccharides, Male, Mice, Inbred C57BL, Niacinamide
Added May 31, 2018
0 Communities
1 Members
0 Resources
10 MeSH Terms
Vildagliptin ameliorates pulmonary fibrosis in lipopolysaccharide-induced lung injury by inhibiting endothelial-to-mesenchymal transition.
Suzuki T, Tada Y, Gladson S, Nishimura R, Shimomura I, Karasawa S, Tatsumi K, West J
(2017) Respir Res 18: 177
MeSH Terms: Adamantane, Animals, Dipeptidyl-Peptidase IV Inhibitors, Epithelial-Mesenchymal Transition, Lipopolysaccharides, Lung Injury, Male, Mice, Mice, Inbred C57BL, Nitriles, Pulmonary Fibrosis, Pyrrolidines, Vildagliptin
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Endothelial-to-mesenchymal transition in lipopolysaccharide-induced acute lung injury drives a progenitor cell-like phenotype.
Suzuki T, Tada Y, Nishimura R, Kawasaki T, Sekine A, Urushibara T, Kato F, Kinoshita T, Ikari J, West J, Tatsumi K
(2016) Am J Physiol Lung Cell Mol Physiol 310: L1185-98
MeSH Terms: Acute Lung Injury, Animals, Apoptosis, Cell Proliferation, Cell Transdifferentiation, Cells, Cultured, Endothelial Progenitor Cells, Endothelium, Vascular, Female, Gene Expression, Lipopolysaccharides, Mice, Inbred C57BL, NADPH Oxidases, Phenotype, Reactive Oxygen Species, Transforming Growth Factor beta1, Transforming Growth Factor beta2
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Cell-free hemoglobin: a novel mediator of acute lung injury.
Shaver CM, Upchurch CP, Janz DR, Grove BS, Putz ND, Wickersham NE, Dikalov SI, Ware LB, Bastarache JA
(2016) Am J Physiol Lung Cell Mol Physiol 310: L532-41
MeSH Terms: Acute Lung Injury, Alveolar Epithelial Cells, Animals, Biomarkers, Cell Line, Cell Membrane Permeability, Cytokines, Hemoglobins, Humans, Lipopolysaccharides, Lung, Mice, Inbred C57BL, Respiratory Distress Syndrome
Added February 17, 2016
0 Communities
2 Members
0 Resources
13 MeSH Terms
Regulation of alveolar procoagulant activity and permeability in direct acute lung injury by lung epithelial tissue factor.
Shaver CM, Grove BS, Putz ND, Clune JK, Lawson WE, Carnahan RH, Mackman N, Ware LB, Bastarache JA
(2015) Am J Respir Cell Mol Biol 53: 719-27
MeSH Terms: Acute Lung Injury, Animals, Blood Coagulation, Capillary Permeability, Disease Models, Animal, Epithelial Cells, Gene Expression, Hemorrhage, Lipopolysaccharides, Mice, Mice, Knockout, Myeloid Cells, Pulmonary Alveoli, Respiratory Distress Syndrome, Respiratory Mucosa, Thromboplastin
Added February 12, 2016
0 Communities
2 Members
0 Resources
16 MeSH Terms
Clinical and biological heterogeneity in acute respiratory distress syndrome: direct versus indirect lung injury.
Shaver CM, Bastarache JA
(2014) Clin Chest Med 35: 639-53
MeSH Terms: Acute Lung Injury, Animals, Disease Models, Animal, Humans, Respiratory Distress Syndrome, Risk Factors
Added January 28, 2015
0 Communities
1 Members
0 Resources
6 MeSH Terms
Differential role for p120-catenin in regulation of TLR4 signaling in macrophages.
Yang Z, Sun D, Yan Z, Reynolds AB, Christman JW, Minshall RD, Malik AB, Zhang Y, Hu G
(2014) J Immunol 193: 1931-41
MeSH Terms: Acute Lung Injury, Adaptor Proteins, Vesicular Transport, Animals, Bronchoalveolar Lavage Fluid, Catenins, Cells, Cultured, Endocytosis, Interferon Regulatory Factor-3, Interferon-beta, Interleukin-6, Leukocyte Count, Lipopolysaccharides, Macrophages, Alveolar, Male, Mice, Mice, Inbred C57BL, Myeloid Differentiation Factor 88, NF-kappa B, Neutrophils, Protein Transport, RNA Interference, Signal Transduction, Toll-Like Receptor 2, Toll-Like Receptor 3, Toll-Like Receptor 4, Tumor Necrosis Factor-alpha, rhoA GTP-Binding Protein
Added May 2, 2016
1 Communities
1 Members
0 Resources
27 MeSH Terms