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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 33

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Simplified LC/MS assay for the measurement of isolevuglandin protein adducts in plasma and tissue samples.
Yermalitsky VN, Matafonova E, Tallman K, Li Z, Zackert W, Roberts LJ, Amarnath V, Davies SS
(2019) Anal Biochem 566: 89-101
MeSH Terms: Aldehydes, Animals, Chromatography, Liquid, Ketones, Lipids, Mice, Mice, Inbred C57BL, Protein Processing, Post-Translational, Proteins, Tandem Mass Spectrometry
Added July 17, 2019
1 Communities
1 Members
0 Resources
10 MeSH Terms
Modification by isolevuglandins, highly reactive γ-ketoaldehydes, deleteriously alters high-density lipoprotein structure and function.
May-Zhang LS, Yermalitsky V, Huang J, Pleasent T, Borja MS, Oda MN, Jerome WG, Yancey PG, Linton MF, Davies SS
(2018) J Biol Chem 293: 9176-9187
MeSH Terms: Aldehydes, Animals, Apolipoprotein A-I, Apolipoprotein A-II, Cells, Cultured, Cholesterol, Female, Humans, Hyperlipoproteinemia Type II, Ketones, Lipid Metabolism, Lipids, Lipoproteins, HDL, Macrophages, Male, Mice, Mice, Inbred C57BL, Phosphatidylethanolamines
Added August 3, 2018
1 Communities
4 Members
0 Resources
18 MeSH Terms
To Avoid Chasing Incorrect Chemical Structures of Chiral Compounds: Raman Optical Activity and Vibrational Circular Dichroism Spectroscopies.
Polavarapu PL, Covington CL, Raghavan V
(2017) Chemphyschem 18: 2459-2465
MeSH Terms: Alcohols, Alkynes, Circular Dichroism, Furans, Ketones, Lactones, Molecular Structure, Quantum Theory, Sesquiterpenes, Spectrum Analysis, Raman
Added April 10, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Electrophilic Modification of PKM2 by 4-Hydroxynonenal and 4-Oxononenal Results in Protein Cross-Linking and Kinase Inhibition.
Camarillo JM, Ullery JC, Rose KL, Marnett LJ
(2017) Chem Res Toxicol 30: 635-641
MeSH Terms: Aldehydes, Cell Line, Tumor, Chromatography, Liquid, Click Chemistry, Enzyme Inhibitors, Humans, Ketones, Pyruvate Kinase, Tandem Mass Spectrometry
Added April 22, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition.
Wood MR, Noetzel MJ, Tarr JC, Rodriguez AL, Lamsal A, Chang S, Foster JJ, Smith E, Chase P, Hodder PS, Engers DW, Niswender CM, Brandon NJ, Wood MW, Duggan ME, Conn PJ, Bridges TM, Lindsley CW
(2016) Bioorg Med Chem Lett 26: 4282-6
MeSH Terms: Allosteric Regulation, Animals, Central Nervous System, Drug Discovery, Humans, Ketones, Molecular Structure, Receptor, Muscarinic M1, Structure-Activity Relationship
Added April 6, 2017
0 Communities
2 Members
0 Resources
9 MeSH Terms
A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells.
Hight MR, Cheung YY, Nickels ML, Dawson ES, Zhao P, Saleh S, Buck JR, Tang D, Washington MK, Coffey RJ, Manning HC
(2014) Clin Cancer Res 20: 2126-35
MeSH Terms: Amino Acid Chloromethyl Ketones, Animals, Apoptosis, Caspase 3, Caspase Inhibitors, Cell Line, Tumor, Colonic Neoplasms, Colorectal Neoplasms, Female, Fluorine Radioisotopes, Fluorobenzenes, Humans, Imidazoles, Immunoblotting, Immunohistochemistry, Indoles, Mice, Inbred C57BL, Mice, Nude, Organophosphates, Peptides, Positron-Emission Tomography, Protein Kinase Inhibitors, Quinazolines, Quinolines, Radiopharmaceuticals, Sulfonamides, Tissue Distribution, Xenograft Model Antitumor Assays
Added March 20, 2014
1 Communities
3 Members
0 Resources
28 MeSH Terms
Preconditioning mesenchymal stem cells with caspase inhibition and hyperoxia prior to hypoxia exposure increases cell proliferation.
Saini U, Gumina RJ, Wolfe B, Kuppusamy ML, Kuppusamy P, Boudoulas KD
(2013) J Cell Biochem 114: 2612-23
MeSH Terms: Amino Acid Chloromethyl Ketones, Animals, Caspase 1, Caspase 3, Caspase 6, Caspase 7, Caspase 9, Cell Hypoxia, Cell Proliferation, Cells, Cultured, Male, Mesenchymal Stem Cells, Rats
Added February 21, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Site-specific AGE modifications in the extracellular matrix: a role for glyoxal in protein damage in diabetes.
Voziyan P, Brown KL, Chetyrkin S, Hudson B
(2014) Clin Chem Lab Med 52: 39-45
MeSH Terms: Aldehydes, Diabetes Mellitus, Extracellular Matrix, Extracellular Matrix Proteins, Glycation End Products, Advanced, Glyoxal, Humans, Ketones
Added February 25, 2014
1 Communities
3 Members
0 Resources
8 MeSH Terms
High-throughput quantification of bioactive lipids by MALDI mass spectrometry: application to prostaglandins.
Manna JD, Reyzer ML, Latham JC, Weaver CD, Marnett LJ, Caprioli RM
(2011) Anal Chem 83: 6683-8
MeSH Terms: Animals, Cell Line, Tumor, Cyclooxygenase 2, High-Throughput Screening Assays, Ketones, Lipids, Metabolome, Mice, Prostaglandins, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Added March 7, 2014
1 Communities
3 Members
0 Resources
10 MeSH Terms
Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030.
Lin L, Liu Y, Li H, Li PK, Fuchs J, Shibata H, Iwabuchi Y, Lin J
(2011) Br J Cancer 105: 212-20
MeSH Terms: Animals, Antineoplastic Agents, Benzene Derivatives, Carcinoma, Cell Line, Tumor, Colonic Neoplasms, Curcumin, Drug Delivery Systems, Female, HCT116 Cells, HT29 Cells, Humans, Ketones, Mice, Mice, Inbred NOD, Mice, SCID, Neoplastic Stem Cells, Xenograft Model Antitumor Assays
Added June 14, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms