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Editorial: Role of CD1- and MR1-Restricted T Cells in Immunity and Disease.
Iwabuchi K, Van Kaer L
(2019) Front Immunol 10: 1837
MeSH Terms: Animals, Antigens, CD1, Histocompatibility Antigens Class I, Humans, Minor Histocompatibility Antigens, Mucosal-Associated Invariant T Cells, Natural Killer T-Cells, Receptors, Antigen, T-Cell, T-Lymphocytes
Added March 3, 2020
0 Communities
1 Members
0 Resources
9 MeSH Terms
NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines.
van Montfoort N, Borst L, Korrer MJ, Sluijter M, Marijt KA, Santegoets SJ, van Ham VJ, Ehsan I, Charoentong P, André P, Wagtmann N, Welters MJP, Kim YJ, Piersma SJ, van der Burg SH, van Hall T
(2018) Cell 175: 1744-1755.e15
MeSH Terms: Animals, Antibodies, Neoplasm, Antigens, CD, CD8-Positive T-Lymphocytes, Cancer Vaccines, Cell Line, Tumor, Histocompatibility Antigens Class I, Humans, Immunity, Cellular, Integrin alpha Chains, Mice, NK Cell Lectin-Like Receptor Subfamily C, Neoplasm Proteins, Neoplasms, Experimental, Vaccination
Added December 11, 2020
2 Communities
0 Members
0 Resources
MeSH Terms
Biological Consequences of MHC-II Expression by Tumor Cells in Cancer.
Axelrod ML, Cook RS, Johnson DB, Balko JM
(2019) Clin Cancer Res 25: 2392-2402
MeSH Terms: Animals, Antigen Presentation, Antigen-Presenting Cells, Biomarkers, CD4-Positive T-Lymphocytes, Disease Management, Disease Models, Animal, Disease Susceptibility, Gene Expression, Gene Expression Regulation, Neoplastic, Histocompatibility Antigens Class I, Histocompatibility Antigens Class II, Humans, Immunotherapy, Neoplasms, Signal Transduction
Added April 15, 2019
0 Communities
1 Members
0 Resources
16 MeSH Terms
Host Expression of the CD8 Treg/NK Cell Restriction Element Qa-1 is Dispensable for Transplant Tolerance.
Stocks BT, Wilson CS, Marshall AF, Brewer LA, Moore DJ
(2017) Sci Rep 7: 11181
MeSH Terms: Animals, B-Lymphocytes, CD4-Positive T-Lymphocytes, Histocompatibility Antigens Class I, Immune Tolerance, Killer Cells, Natural, Mice, Inbred C57BL, Mice, Knockout, T-Lymphocytes, Regulatory, Transplantation
Added September 13, 2017
0 Communities
1 Members
0 Resources
10 MeSH Terms
Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles.
Pavlos R, McKinnon EJ, Ostrov DA, Peters B, Buus S, Koelle D, Chopra A, Schutte R, Rive C, Redwood A, Restrepo S, Bracey A, Kaever T, Myers P, Speers E, Malaker SA, Shabanowitz J, Jing Y, Gaudieri S, Hunt DF, Carrington M, Haas DW, Mallal S, Phillips EJ
(2017) Sci Rep 7: 8653
MeSH Terms: Alleles, Anti-HIV Agents, Case-Control Studies, Disease Susceptibility, Drug Hypersensitivity, Histocompatibility Antigens Class I, Histocompatibility Antigens Class II, Humans, Nevirapine, Odds Ratio, Peptides, Protein Binding, Risk Assessment, T-Lymphocytes
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Autophagy-related protein Vps34 controls the homeostasis and function of antigen cross-presenting CD8α dendritic cells.
Parekh VV, Pabbisetty SK, Wu L, Sebzda E, Martinez J, Zhang J, Van Kaer L
(2017) Proc Natl Acad Sci U S A 114: E6371-E6380
MeSH Terms: Animals, Antigen Presentation, Autophagy, Autophagy-Related Proteins, CD8 Antigens, CD8-Positive T-Lymphocytes, Cells, Cultured, Class III Phosphatidylinositol 3-Kinases, Cross-Priming, Cytokines, Dendritic Cells, Endocytosis, Histocompatibility Antigens Class I, Melanoma, Experimental, Membrane Proteins, Mice, Mice, Knockout, Phagocytosis
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants.
Karnes JH, Bastarache L, Shaffer CM, Gaudieri S, Xu Y, Glazer AM, Mosley JD, Zhao S, Raychaudhuri S, Mallal S, Ye Z, Mayer JG, Brilliant MH, Hebbring SJ, Roden DM, Phillips EJ, Denny JC
(2017) Sci Transl Med 9:
MeSH Terms: Alleles, Diabetes Mellitus, Type 1, Genetic Predisposition to Disease, Genome-Wide Association Study, HLA-DQ beta-Chains, Histocompatibility Antigens Class II, Humans, Polymorphism, Single Nucleotide
Added March 14, 2018
0 Communities
3 Members
0 Resources
8 MeSH Terms
Expression Quantitative Trait Locus Mapping Studies in Mid-secretory Phase Endometrial Cells Identifies HLA-F and TAP2 as Fecundability-Associated Genes.
Burrows CK, Kosova G, Herman C, Patterson K, Hartmann KE, Velez Edwards DR, Stephenson MD, Lynch VJ, Ober C
(2016) PLoS Genet 12: e1005858
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 3, Adult, Chromosome Mapping, Endometrium, Female, Fertility, Gene Expression Regulation, Genetic Predisposition to Disease, Genome-Wide Association Study, Histocompatibility Antigens Class I, Humans, Phenotype, Polymorphism, Single Nucleotide, Pregnancy, Quantitative Trait Loci, Regulatory Sequences, Nucleic Acid
Added February 21, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Viral infection causes a shift in the self peptide repertoire presented by human MHC class I molecules.
Spencer CT, Bezbradica JS, Ramos MG, Arico CD, Conant SB, Gilchuk P, Gray JJ, Zheng M, Niu X, Hildebrand W, Link AJ, Joyce S
(2015) Proteomics Clin Appl 9: 1035-52
MeSH Terms: Amino Acid Sequence, Antigen Presentation, Cell Line, Histocompatibility Antigens Class I, Humans, Molecular Sequence Data, Oncogenes, Peptides, Proteomics, Vaccinia virus
Added February 15, 2016
0 Communities
2 Members
0 Resources
10 MeSH Terms
Penetrance of Hemochromatosis in HFE Genotypes Resulting in p.Cys282Tyr and p.[Cys282Tyr];[His63Asp] in the eMERGE Network.
Gallego CJ, Burt A, Sundaresan AS, Ye Z, Shaw C, Crosslin DR, Crane PK, Fullerton SM, Hansen K, Carrell D, Kuivaniemi H, Derr K, de Andrade M, McCarty CA, Kitchner TE, Ragon BK, Stallings SC, Papa G, Bochenek J, Smith ME, Aufox SA, Pacheco JA, Patel V, Friesema EM, Erwin AL, Gottesman O, Gerhard GS, Ritchie M, Motulsky AG, Kullo IJ, Larson EB, Tromp G, Brilliant MH, Bottinger E, Denny JC, Roden DM, Williams MS, Jarvik GP
(2015) Am J Hum Genet 97: 512-20
MeSH Terms: Adult, Aged, Amino Acid Substitution, Child, Cohort Studies, Female, Follow-Up Studies, Genetic Variation, Genotype, Hemochromatosis, Hemochromatosis Protein, Heterozygote, Histocompatibility Antigens Class I, Homozygote, Humans, Male, Membrane Proteins, Middle Aged, Penetrance, Prognosis, United States
Added March 14, 2018
0 Communities
2 Members
0 Resources
21 MeSH Terms