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Results: 1 to 10 of 37

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Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans.
Jeff JM, Armstrong LL, Ritchie MD, Denny JC, Kho AN, Basford MA, Wolf WA, Pacheco JA, Li R, Chisholm RL, Roden DM, Hayes MG, Crawford DC
(2014) PLoS One 9: e86931
MeSH Terms: Blacks, Chromosome Mapping, Chromosomes, Human, Pair 11, Diabetes Mellitus, Type 2, Genome-Wide Association Study, Humans, Linkage Disequilibrium, Polymorphism, Single Nucleotide
Added May 23, 2014
0 Communities
3 Members
0 Resources
8 MeSH Terms
Cytogenetic prognostication within medulloblastoma subgroups.
Shih DJ, Northcott PA, Remke M, Korshunov A, Ramaswamy V, Kool M, Luu B, Yao Y, Wang X, Dubuc AM, Garzia L, Peacock J, Mack SC, Wu X, Rolider A, Morrissy AS, Cavalli FM, Jones DT, Zitterbart K, Faria CC, Schüller U, Kren L, Kumabe T, Tominaga T, Shin Ra Y, Garami M, Hauser P, Chan JA, Robinson S, Bognár L, Klekner A, Saad AG, Liau LM, Albrecht S, Fontebasso A, Cinalli G, De Antonellis P, Zollo M, Cooper MK, Thompson RC, Bailey S, Lindsey JC, Di Rocco C, Massimi L, Michiels EM, Scherer SW, Phillips JJ, Gupta N, Fan X, Muraszko KM, Vibhakar R, Eberhart CG, Fouladi M, Lach B, Jung S, Wechsler-Reya RJ, Fèvre-Montange M, Jouvet A, Jabado N, Pollack IF, Weiss WA, Lee JY, Cho BK, Kim SK, Wang KC, Leonard JR, Rubin JB, de Torres C, Lavarino C, Mora J, Cho YJ, Tabori U, Olson JM, Gajjar A, Packer RJ, Rutkowski S, Pomeroy SL, French PJ, Kloosterhof NK, Kros JM, Van Meir EG, Clifford SC, Bourdeaut F, Delattre O, Doz FF, Hawkins CE, Malkin D, Grajkowska WA, Perek-Polnik M, Bouffet E, Rutka JT, Pfister SM, Taylor MD
(2014) J Clin Oncol 32: 886-96
MeSH Terms: Adolescent, Biomarkers, Tumor, Child, Child, Preschool, Chromosomes, Human, Pair 11, Chromosomes, Human, Pair 14, Cytogenetics, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Hedgehog Proteins, Humans, In Situ Hybridization, Fluorescence, Infant, Kruppel-Like Transcription Factors, Male, Medulloblastoma, Nuclear Proteins, Predictive Value of Tests, Prognosis, Proportional Hazards Models, Proto-Oncogene Proteins c-myc, Reproducibility of Results, Risk Assessment, Risk Factors, Tissue Array Analysis, Wnt Proteins, Young Adult, Zinc Finger Protein Gli2
Added March 21, 2014
0 Communities
1 Members
0 Resources
29 MeSH Terms
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers.
French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D, Tessier DC, Vincent D, Bacot F, Luccarini C, Baynes C, Conroy D, Dennis J, Bolla MK, Wang Q, Hopper JL, Southey MC, Schmidt MK, Broeks A, Verhoef S, Cornelissen S, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Loehberg CR, Ekici AB, Beckmann MW, Peto J, dos Santos Silva I, Johnson N, Aitken Z, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Guénel P, Truong T, Laurent-Puig P, Menegaux F, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Milne RL, Zamora MP, Arias Perez JI, Benitez J, Anton-Culver H, Brenner H, Müller H, Arndt V, Stegmaier C, Meindl A, Lichtner P, Schmutzler RK, Engel C, Brauch H, Hamann U, Justenhoven C, GENICA Network, Aaltonen K, Heikkilä P, Aittomäki K, Blomqvist C, Matsuo K, Ito H, Iwata H, Sueta A, Bogdanova NV, Antonenkova NN, Dörk T, Lindblom A, Margolin S, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, kConFab Investigators, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Lambrechts D, Peeters S, Smeets A, Floris G, Chang-Claude J, Rudolph A, Nickels S, Flesch-Janys D, Radice P, Peterlongo P, Bonanni B, Sardella D, Couch FJ, Wang X, Pankratz VS, Lee A, Giles GG, Severi G, Baglietto L, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Simard J, Goldberg MS, Labrèche F, Dumont M, Teo SH, Yip CH, Ng CH, Vithana EN, Kristensen V, Zheng W, Deming-Halverson S, Shrubsole M, Long J, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Devilee P, Seynaeve C, García-Closas M, Figueroa J, Chanock SJ, Lissowska J, Czene K, Klevebring D, Schoof N, Hooning MJ, Martens JW, Collée JM, Tilanus-Linthorst M, Hall P, Li J, Liu J, Humphreys K, Shu XO, Lu W, Gao YT, Cai H, Cox A, Balasubramanian SP, Blot W, Signorello LB, Cai Q, Pharoah PD, Healey CS, Shah M, Pooley KA, Kang D, Yoo KY, Noh DY, Hartman M, Miao H, Sng JH, Sim X, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Sangrajrang S, Gaborieau V, McKay J, Toland AE, Ambrosone CB, Yannoukakos D, Godwin AK, Shen CY, Hsiung CN, Wu PE, Chen ST, Swerdlow A, Ashworth A, Orr N, Schoemaker MJ, Ponder BA, Nevanlinna H, Brown MA, Chenevix-Trench G, Easton DF, Dunning AM
(2013) Am J Hum Genet 92: 489-503
MeSH Terms: Binding Sites, Breast Neoplasms, Case-Control Studies, Cell Line, Tumor, Chromatin, Chromatin Immunoprecipitation, Chromosomes, Human, Pair 11, Cyclin D1, Electrophoretic Mobility Shift Assay, Enhancer Elements, Genetic, Female, GATA3 Transcription Factor, Gene Expression Regulation, Neoplastic, Humans, Luciferases, Polymorphism, Single Nucleotide, Promoter Regions, Genetic, RNA, Messenger, RNA, Small Interfering, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Silencer Elements, Transcriptional, ets-Domain Protein Elk-4
Added March 10, 2014
0 Communities
2 Members
0 Resources
23 MeSH Terms
Circulating CD34(+) progenitor cell frequency is associated with clinical and genetic factors.
Cohen KS, Cheng S, Larson MG, Cupples LA, McCabe EL, Wang YA, Ngwa JS, Martin RP, Klein RJ, Hashmi B, Ge Y, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ
(2013) Blood 121: e50-6
MeSH Terms: Aged, Antigens, CD34, Biomarkers, Tumor, Cardiovascular Diseases, Carrier Proteins, Chromosomes, Human, Pair 1, Chromosomes, Human, Pair 11, DNA-Binding Proteins, Female, Genome-Wide Association Study, Hematopoiesis, Hematopoietic Stem Cells, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Male, Massachusetts, Middle Aged, Oligonucleotide Array Sequence Analysis, Phosphopyruvate Hydratase, Prevalence, Risk Factors, Sex Distribution, Smoking, Tumor Suppressor Proteins
Added April 15, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer.
Long J, Cai Q, Sung H, Shi J, Zhang B, Choi JY, Wen W, Delahanty RJ, Lu W, Gao YT, Shen H, Park SK, Chen K, Shen CY, Ren Z, Haiman CA, Matsuo K, Kim MK, Khoo US, Iwasaki M, Zheng Y, Xiang YB, Gu K, Rothman N, Wang W, Hu Z, Liu Y, Yoo KY, Noh DY, Han BG, Lee MH, Zheng H, Zhang L, Wu PE, Shieh YL, Chan SY, Wang S, Xie X, Kim SW, Henderson BE, Le Marchand L, Ito H, Kasuga Y, Ahn SH, Kang HS, Chan KY, Iwata H, Tsugane S, Li C, Shu XO, Kang DH, Zheng W
(2012) PLoS Genet 8: e1002532
MeSH Terms: Adaptor Proteins, Signal Transducing, Adult, Asians, Breast Neoplasms, Chromosomes, Human, Pair 11, Chromosomes, Human, Pair 6, Estrogen Receptor alpha, Far East, Female, Genetic Loci, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Middle Aged
Added December 10, 2013
0 Communities
4 Members
0 Resources
14 MeSH Terms
Common genetic determinants of vitamin D insufficiency: a genome-wide association study.
Wang TJ, Zhang F, Richards JB, Kestenbaum B, van Meurs JB, Berry D, Kiel DP, Streeten EA, Ohlsson C, Koller DL, Peltonen L, Cooper JD, O'Reilly PF, Houston DK, Glazer NL, Vandenput L, Peacock M, Shi J, Rivadeneira F, McCarthy MI, Anneli P, de Boer IH, Mangino M, Kato B, Smyth DJ, Booth SL, Jacques PF, Burke GL, Goodarzi M, Cheung CL, Wolf M, Rice K, Goltzman D, Hidiroglou N, Ladouceur M, Wareham NJ, Hocking LJ, Hart D, Arden NK, Cooper C, Malik S, Fraser WD, Hartikainen AL, Zhai G, Macdonald HM, Forouhi NG, Loos RJ, Reid DM, Hakim A, Dennison E, Liu Y, Power C, Stevens HE, Jaana L, Vasan RS, Soranzo N, Bojunga J, Psaty BM, Lorentzon M, Foroud T, Harris TB, Hofman A, Jansson JO, Cauley JA, Uitterlinden AG, Gibson Q, Järvelin MR, Karasik D, Siscovick DS, Econs MJ, Kritchevsky SB, Florez JC, Todd JA, Dupuis J, Hyppönen E, Spector TD
(2010) Lancet 376: 180-8
MeSH Terms: Canada, Chromosomes, Human, Pair 11, Chromosomes, Human, Pair 4, Cohort Studies, Dietary Supplements, Europe, Genetic Predisposition to Disease, Genome-Wide Association Study, Heterozygote, Homozygote, Humans, Immunoassay, International Cooperation, Linkage Disequilibrium, Polymorphism, Single Nucleotide, Seasons, United States, Vitamin D, Vitamin D Deficiency, Whites
Added April 15, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Examination of tetrahydrobiopterin pathway genes in autism.
Schnetz-Boutaud NC, Anderson BM, Brown KD, Wright HH, Abramson RK, Cuccaro ML, Gilbert JR, Pericak-Vance MA, Haines JL
(2009) Genes Brain Behav 8: 753-7
MeSH Terms: Adolescent, Autistic Disorder, Biopterin, Brain, Child, Child, Preschool, Chromosomes, Human, Pair 11, DNA Mutational Analysis, Female, Gene Expression Regulation, Genetic Markers, Genetic Predisposition to Disease, Genetic Testing, Genotype, Humans, Male, Phosphorus-Oxygen Lyases, Polymorphism, Single Nucleotide, Signal Transduction, Young Adult
Added March 5, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Aggressiveness of HNSCC tumors depends on expression levels of cortactin, a gene in the 11q13 amplicon.
Clark ES, Brown B, Whigham AS, Kochaishvili A, Yarbrough WG, Weaver AM
(2009) Oncogene 28: 431-44
MeSH Terms: Animals, Apoptosis, Autocrine Communication, Carcinoma, Squamous Cell, Cell Proliferation, Chromosomes, Human, Pair 11, Coculture Techniques, Cortactin, Gene Expression Regulation, Neoplastic, Head and Neck Neoplasms, Humans, Mice, Mice, Nude, Neoplasm Invasiveness, Nerve Growth Factors, RNA, Small Interfering, Rats, Trachea, Tumor Cells, Cultured
Added March 5, 2014
1 Communities
1 Members
0 Resources
19 MeSH Terms
Chromosomal microarray mapping suggests a role for BSX and Neurogranin in neurocognitive and behavioral defects in the 11q terminal deletion disorder (Jacobsen syndrome).
Coldren CD, Lai Z, Shragg P, Rossi E, Glidewell SC, Zuffardi O, Mattina T, Ivy DD, Curfs LM, Mattson SN, Riley EP, Treier M, Grossfeld PD
(2009) Neurogenetics 10: 89-95
MeSH Terms: Adolescent, Adult, Animals, Child, Chromosome Deletion, Chromosome Mapping, Chromosomes, Human, Pair 11, Cognition Disorders, Female, Homeodomain Proteins, Humans, Jacobsen Distal 11q Deletion Syndrome, Male, Mental Disorders, Mice, Microarray Analysis, Nerve Tissue Proteins, Neurogranin, Prospective Studies, Young Adult
Added November 17, 2011
0 Communities
1 Members
0 Resources
20 MeSH Terms
Genome-wide linkage analyses of quantitative and categorical autism subphenotypes.
Liu XQ, Paterson AD, Szatmari P, Autism Genome Project Consortium
(2008) Biol Psychiatry 64: 561-70
MeSH Terms: Autistic Disorder, Child, Chromosomes, Human, Pair 11, Chromosomes, Human, Pair 15, Female, Genetic Linkage, Genetic Markers, Genome-Wide Association Study, Humans, Interpersonal Relations, Male, Phenotype, Verbal Behavior
Added February 20, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms