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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 71

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The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling.
Shen C, Nayak A, Neitzel LR, Adams AA, Silver-Isenstadt M, Sawyer LM, Benchabane H, Wang H, Bunnag N, Li B, Wynn DT, Yang F, Garcia-Contreras M, Williams CH, Dakshanamurthy S, Hong CC, Ayad NG, Capobianco AJ, Ahmed Y, Lee E, Robbins DJ
(2021) Nat Commun 12: 5263
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Casein Kinase Ialpha, Drosophila Proteins, Drosophila melanogaster, Embryo, Nonmammalian, Evolution, Molecular, HEK293 Cells, Humans, Immunologic Factors, Lenalidomide, Mice, Organoids, Peptide Hydrolases, Ubiquitin-Protein Ligases, Ubiquitination, Wnt Signaling Pathway, Zebrafish, Zebrafish Proteins
Added September 11, 2021
0 Communities
1 Members
0 Resources
19 MeSH Terms
Cell differentiation is disrupted by MYO5B loss through Wnt/Notch imbalance.
Kaji I, Roland JT, Rathan-Kumar S, Engevik AC, Burman A, Goldstein AE, Watanabe M, Goldenring JR
(2021) JCI Insight 6:
MeSH Terms: Animals, Cell Differentiation, Cells, Cultured, Dibenzazepines, Disease Models, Animal, Enterocytes, Humans, Intestinal Mucosa, Jejunum, Lysophospholipids, Malabsorption Syndromes, Mice, Mice, Knockout, Microvilli, Mucolipidoses, Myosin Type V, Organoids, Primary Cell Culture, Receptors, Notch, Stem Cells, Wnt Signaling Pathway
Added August 16, 2021
1 Communities
0 Members
0 Resources
21 MeSH Terms
Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation during zebrafish heart regeneration.
Peng X, Lai KS, She P, Kang J, Wang T, Li G, Zhou Y, Sun J, Jin D, Xu X, Liao L, Liu J, Lee E, Poss KD, Zhong TP
(2021) J Mol Cell Biol 13: 41-58
MeSH Terms: Animals, Cell Proliferation, Disease Models, Animal, Heart Injuries, Humans, Intercellular Signaling Peptides and Proteins, Myocytes, Cardiac, Protein Serine-Threonine Kinases, Regeneration, Sarcomeres, Wnt Signaling Pathway, Zebrafish, Zebrafish Proteins, beta Catenin
Added June 6, 2022
0 Communities
1 Members
0 Resources
MeSH Terms
Casein Kinase 1α as a Regulator of Wnt-Driven Cancer.
Shen C, Nayak A, Melendez RA, Wynn DT, Jackson J, Lee E, Ahmed Y, Robbins DJ
(2020) Int J Mol Sci 21:
MeSH Terms: Animals, Antineoplastic Agents, Casein Kinase Ialpha, Enzyme Activators, Humans, Neoplasms, Wnt Signaling Pathway
Added August 24, 2020
0 Communities
1 Members
0 Resources
7 MeSH Terms
Nuclear Regulation of Wnt/β-Catenin Signaling: It's a Complex Situation.
Anthony CC, Robbins DJ, Ahmed Y, Lee E
(2020) Genes (Basel) 11:
MeSH Terms: Active Transport, Cell Nucleus, Animals, Cell Nucleus, Gene Expression Regulation, Developmental, Humans, Wnt Signaling Pathway, beta Catenin
Added August 10, 2020
0 Communities
1 Members
0 Resources
7 MeSH Terms
Single-Cell Analyses Confirm the Critical Role of LRP6 for Wnt Signaling in APC-Deficient Cells.
Cabel CR, Alizadeh E, Robbins DJ, Ahmed Y, Lee E, Thorne CA
(2019) Dev Cell 49: 827-828
MeSH Terms: Clathrin, Low Density Lipoprotein Receptor-Related Protein-6, Single-Cell Analysis, Wnt Signaling Pathway
Added July 23, 2019
0 Communities
1 Members
0 Resources
4 MeSH Terms
Discovering small molecules as Wnt inhibitors that promote heart regeneration and injury repair.
Xie S, Fu W, Yu G, Hu X, Lai KS, Peng X, Zhou Y, Zhu X, Christov P, Sawyer L, Ni TT, Sulikowski GA, Yang Z, Lee E, Zeng C, Wang WE, Zhong TP
(2020) J Mol Cell Biol 12: 42-54
MeSH Terms: Animals, Animals, Genetically Modified, Cell Differentiation, Cell Line, Cell Proliferation, Disease Models, Animal, Heart Injuries, Male, Mice, Mice, Inbred C57BL, Mouse Embryonic Stem Cells, Myocardial Infarction, Myocytes, Cardiac, Regenerative Medicine, Signal Transduction, Small Molecule Libraries, Wnt Proteins, Wnt Signaling Pathway, Wound Healing, Zebrafish, Zebrafish Proteins, beta Catenin
Added April 10, 2019
0 Communities
1 Members
0 Resources
22 MeSH Terms
Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway.
Neitzel LR, Spencer ZT, Nayak A, Cselenyi CS, Benchabane H, Youngblood CQ, Zouaoui A, Ng V, Stephens L, Hann T, Patton JG, Robbins D, Ahmed Y, Lee E
(2019) Mech Dev 156: 20-31
MeSH Terms: Animals, Body Patterning, Drosophila, Embryonic Development, Evolution, Molecular, Gene Expression Regulation, Developmental, Glycosylation, Humans, Phosphotransferases (Alcohol Group Acceptor), Wnt Signaling Pathway, Xenopus laevis, Zebrafish
Added April 10, 2019
0 Communities
1 Members
0 Resources
12 MeSH Terms
Bergmann glial Sonic hedgehog signaling activity is required for proper cerebellar cortical expansion and architecture.
Cheng FY, Fleming JT, Chiang C
(2018) Dev Biol 440: 152-166
MeSH Terms: Animals, Astrocytes, Cell Differentiation, Cell Division, Cell Proliferation, Cells, Cultured, Cerebellar Cortex, Cerebellar Neoplasms, Cerebellum, Developmental Disabilities, Hedgehog Proteins, Mice, Nervous System Malformations, Neural Stem Cells, Neuroglia, Neurons, Purkinje Cells, Signal Transduction, Wnt Signaling Pathway
Added April 10, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling.
Ng VH, Hang BI, Sawyer LM, Neitzel LR, Crispi EE, Rose KL, Popay TM, Zhong A, Lee LA, Tansey WP, Huppert S, Lee E
(2018) J Cell Sci 131:
MeSH Terms: Amino Acid Motifs, Animals, Apoptosis Regulatory Proteins, Cell Line, Glycogen Synthase Kinase 3, Humans, Intracellular Signaling Peptides and Proteins, Mitochondrial Proteins, Phosphorylation, Protein Binding, Threonine, Wnt Signaling Pathway, Wnt3A Protein, X-Linked Inhibitor of Apoptosis Protein, Xenopus
Added July 6, 2018
0 Communities
2 Members
0 Resources
15 MeSH Terms