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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 23

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ROCK-nmMyoII, Notch and gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche.
Bankaitis ED, Bechard ME, Gu G, Magnuson MA, Wright CVE
(2018) Development 145:
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Differentiation, Cell Movement, Endocrine Cells, Gene Dosage, Mice, Mice, Transgenic, Nerve Tissue Proteins, Organogenesis, Pancreas, Receptors, Notch, Stem Cells, Transcriptional Activation, rho-Associated Kinases
Added August 24, 2018
3 Communities
2 Members
0 Resources
15 MeSH Terms
Oxidative stress, caspase-3 activation and cleavage of ROCK-1 play an essential role in MeHg-induced cell death in primary astroglial cells.
Dos Santos AA, López-Granero C, Farina M, Rocha JBT, Bowman AB, Aschner M
(2018) Food Chem Toxicol 113: 328-336
MeSH Terms: Animals, Astrocytes, Caspase 3, Caspase 9, Cell Death, Cells, Cultured, Enzyme Activation, Lim Kinases, Methylmercury Compounds, Mice, Inbred C57BL, Myosin-Light-Chain Phosphatase, Oxidative Stress, Phosphorylation, Proteolysis, rho-Associated Kinases
Added April 11, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
p120-Catenin is an obligate haploinsufficient tumor suppressor in intestinal neoplasia.
Short SP, Kondo J, Smalley-Freed WG, Takeda H, Dohn MR, Powell AE, Carnahan RH, Washington MK, Tripathi M, Payne DM, Jenkins NA, Copeland NG, Coffey RJ, Reynolds AB
(2017) J Clin Invest 127: 4462-4476
MeSH Terms: Adenomatous Polyposis Coli Protein, Animals, Catenins, Haploinsufficiency, Intestinal Neoplasms, Mice, Mice, Knockout, rho-Associated Kinases
Added March 14, 2018
0 Communities
2 Members
0 Resources
8 MeSH Terms
The Atypical MAP Kinase SWIP-13/ERK8 Regulates Dopamine Transporters through a Rho-Dependent Mechanism.
Bermingham DP, Hardaway JA, Refai O, Marks CR, Snider SL, Sturgeon SM, Spencer WC, Colbran RJ, Miller DM, Blakely RD
(2017) J Neurosci 37: 9288-9304
MeSH Terms: Animals, Animals, Genetically Modified, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Cells, Cultured, Dopamine, Dopamine Plasma Membrane Transport Proteins, Extracellular Signal-Regulated MAP Kinases, Gene Expression Regulation, Enzymologic, Neurons, rho-Associated Kinases
Added March 21, 2018
0 Communities
2 Members
0 Resources
11 MeSH Terms
The ROCK isoforms differentially regulate the morphological characteristics of carcinoma cells.
Jerrell RJ, Leih MJ, Parekh A
(2020) Small GTPases 11: 131-137
MeSH Terms: Carcinoma, Cell Line, Tumor, Cell Movement, Focal Adhesions, Humans, Phenotype, rho-Associated Kinases
Added June 28, 2017
1 Communities
1 Members
0 Resources
7 MeSH Terms
Regulation of arterial reactivity by concurrent signaling through the E-prostanoid receptor 3 and angiotensin receptor 1.
Kraemer MP, Choi H, Reese J, Lamb FS, Breyer RM
(2016) Vascul Pharmacol 84: 47-54
MeSH Terms: Angiotensin II, Animals, Calcium, Dinoprostone, Dose-Response Relationship, Drug, Femoral Artery, Focal Adhesion Kinase 2, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Receptor, Angiotensin, Type 1, Receptors, Prostaglandin E, EP3 Subtype, Vasoconstriction, rho-Associated Kinases
Added April 6, 2017
0 Communities
2 Members
0 Resources
15 MeSH Terms
Matrix rigidity differentially regulates invadopodia activity through ROCK1 and ROCK2.
Jerrell RJ, Parekh A
(2016) Biomaterials 84: 119-129
MeSH Terms: Biomechanical Phenomena, Cell Line, Tumor, Cell Movement, Extracellular Matrix, Humans, Isoenzymes, Lim Kinases, Myosin Type II, Neoplasm Invasiveness, Phosphorylation, Pseudopodia, Signal Transduction, rho-Associated Kinases
Added February 23, 2016
1 Communities
1 Members
0 Resources
13 MeSH Terms
p120-catenin controls contractility along the vertical axis of epithelial lateral membranes.
Yu HH, Dohn MR, Markham NO, Coffey RJ, Reynolds AB
(2016) J Cell Sci 129: 80-94
MeSH Terms: Amino Acid Sequence, Animals, Cadherins, Catenins, Cell Membrane, Cell Polarity, Cell Shape, Dogs, Epithelial Cells, Madin Darby Canine Kidney Cells, Molecular Sequence Data, Nonmuscle Myosin Type IIA, Phenotype, Protein Binding, rho-Associated Kinases, rhoA GTP-Binding Protein
Added May 2, 2016
1 Communities
2 Members
0 Resources
16 MeSH Terms
PTK7-Src signaling at epithelial cell contacts mediates spatial organization of actomyosin and planar cell polarity.
Andreeva A, Lee J, Lohia M, Wu X, Macara IG, Lu X
(2014) Dev Cell 29: 20-33
MeSH Terms: Actomyosin, Animals, Cell Differentiation, Cell Polarity, Cells, Cultured, Cochlea, Dogs, Epithelial Cells, Intercellular Junctions, Madin Darby Canine Kidney Cells, Mice, Phosphorylation, Receptor Protein-Tyrosine Kinases, Signal Transduction, rho-Associated Kinases
Added May 30, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Association of Rho-associated protein kinase 1 with E-cadherin complexes is mediated by p120-catenin.
Smith AL, Dohn MR, Brown MV, Reynolds AB
(2012) Mol Biol Cell 23: 99-110
MeSH Terms: Actins, Cadherins, Catenins, Cell Line, Gene Knockdown Techniques, Guanine Nucleotide Exchange Factors, Humans, Intercellular Junctions, Microscopy, Fluorescence, Multiprotein Complexes, Protein Binding, Protein Interaction Mapping, Protein Transport, RNA Interference, Repressor Proteins, rho-Associated Kinases
Added March 5, 2014
1 Communities
1 Members
0 Resources
16 MeSH Terms