Association of Aortic Stiffness With Biomarkers of Neuroinflammation, Synaptic Dysfunction, and Neurodegeneration.
Moore EE, Liu D, Li J, Schimmel SJ, Cambronero FE, Terry JG, Nair S, Pechman KR, Moore ME, Bell SP, Beckman JA, Gifford KA, Hohman TJ, Blennow K, Zetterberg H, Carr JJ, Jefferson AL
(2021) Neurology 97
: e329-e340MeSH Terms: Aged, Aged, 80 and over, Aging, Amyloid beta-Peptides, Biomarkers, Female, Heart, Humans, Inflammation, Male, Middle Aged, Neurodegenerative Diseases, Phosphorylation, Pulse Wave Analysis, Vascular Stiffness, tau ProteinsAdded June 9, 2021
16 MeSH Terms
Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8 T cells during the primary immune response.
Levine LS, Hiam-Galvez KJ, Marquez DM, Tenvooren I, Madden MZ, Contreras DC, Dahunsi DO, Irish JM, Oluwole OO, Rathmell JC, Spitzer MH
(2021) Immunity 54
: 829-844.e5MeSH Terms: Animals, CD8-Positive T-Lymphocytes, Cell Proliferation, Female, Glycolysis, Immunologic Memory, Listeria monocytogenes, Listeriosis, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Mice, Transgenic, Oxidative Phosphorylation, Receptors, Chimeric Antigen, Signal Transduction, Single-Cell AnalysisAdded March 26, 2021
16 MeSH Terms
RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT.
Kryshtal DO, Blackwell DJ, Egly CL, Smith AN, Batiste SM, Johnston JN, Laver DR, Knollmann BC
(2021) Circ Res 128
: 321-331MeSH Terms: Action Potentials, Animals, Anti-Arrhythmia Agents, Calcium Channel Blockers, Calcium Signaling, Calsequestrin, Disease Models, Animal, Female, Flecainide, HEK293 Cells, Heart Rate, Humans, Male, Mice, Knockout, Myocytes, Cardiac, Phosphorylation, Ryanodine Receptor Calcium Release Channel, Sarcoplasmic Reticulum, Sheep, Domestic, Tachycardia, Ventricular, Voltage-Gated Sodium Channel BlockersAdded December 21, 2020
21 MeSH Terms
Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion via Tau Phosphorylation.
Ho KH, Yang X, Osipovich AB, Cabrera O, Hayashi ML, Magnuson MA, Gu G, Kaverina I
(2020) Diabetes 69
: 1936-1947MeSH Terms: Animals, Cyclic AMP-Dependent Protein Kinases, Cyclin-Dependent Kinase 5, Glucose, Glycogen Synthase Kinase 3, Insulin Secretion, Insulin-Secreting Cells, Mice, Microtubules, Phosphorylation, Protein Kinase C, tau ProteinsAdded July 2, 2020
12 MeSH Terms
Training Novices in Generation and Analysis of High-Dimensional Human Cell Phospho-Flow Cytometry Data.
Roe CE, Hayes MJ, Barone SM, Irish JM
(2020) Curr Protoc Cytom 93
: e71MeSH Terms: Automation, Cells, Data Analysis, Education, Flow Cytometry, Humans, PhosphorylationAdded June 8, 2020
7 MeSH Terms
DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division.
Bhattacharjee R, Mangione MC, Wos M, Chen JS, Snider CE, Roberts-Galbraith RH, McDonald NA, Presti LL, Martin SG, Gould KL
(2020) Mol Biol Cell 31
: 917-929MeSH Terms: Cell Cycle Proteins, Cytokinesis, Cytoskeletal Proteins, GTP-Binding Proteins, Phosphorylation, Protein Kinases, Protein Processing, Post-Translational, Schizosaccharomyces, Schizosaccharomyces pombe ProteinsAdded March 3, 2020
9 MeSH Terms
BRAF molecular testing in cytopathology: Implications for diagnosis, prognosis, and targeted therapeutics.
Bergdorf KN, Lee LA, Weiss VL
(2020) Cancer Cytopathol 128
: 9-11MeSH Terms: Antineoplastic Agents, Genetic Testing, Humans, MAP Kinase Signaling System, Molecular Targeted Therapy, Mutation, Neoplasms, Phosphorylation, Precision Medicine, Prognosis, Proto-Oncogene Proteins B-rafAdded March 3, 2020
11 MeSH Terms
Developmentally regulated KCC2 phosphorylation is essential for dynamic GABA-mediated inhibition and survival.
Watanabe M, Zhang J, Mansuri MS, Duan J, Karimy JK, Delpire E, Alper SL, Lifton RP, Fukuda A, Kahle KT
(2019) Sci Signal 12
: MeSH Terms: Animals, Animals, Newborn, Binding Sites, Cells, Cultured, Central Nervous System, Chlorides, Gene Expression Regulation, Developmental, Male, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Knockout, Neurons, Phosphorylation, Signal Transduction, Symporters, gamma-Aminobutyric AcidAdded March 18, 2020
16 MeSH Terms
Interaction of α Carboxyl Terminus 1 Peptide With the Connexin 43 Carboxyl Terminus Preserves Left Ventricular Function After Ischemia-Reperfusion Injury.
Jiang J, Hoagland D, Palatinus JA, He H, Iyyathurai J, Jourdan LJ, Bultynck G, Wang Z, Zhang Z, Schey K, Poelzing S, McGowan FX, Gourdie RG
(2019) J Am Heart Assoc 8
: e012385MeSH Terms: Animals, Computer Simulation, Connexin 43, Mice, Microscopy, Confocal, Myocardial Contraction, Myocardial Reperfusion Injury, Peptide Fragments, Phosphorylation, Surface Plasmon Resonance, Tandem Mass Spectrometry, Ventricular Function, Left, Zonula Occludens-1 ProteinAdded March 24, 2020
13 MeSH Terms
Normal Saline solutions cause endothelial dysfunction through loss of membrane integrity, ATP release, and inflammatory responses mediated by P2X7R/p38 MAPK/MK2 signaling pathways.
Cheung-Flynn J, Alvis BD, Hocking KM, Guth CM, Luo W, McCallister R, Chadalavada K, Polcz M, Komalavilas P, Brophy CM
(2019) PLoS One 14
: e0220893MeSH Terms: Adenosine Triphosphate, Animals, Aorta, Cell Membrane, Endothelial Cells, Humans, Inflammation, Intracellular Signaling Peptides and Proteins, Phosphorylation, Protein Serine-Threonine Kinases, Rats, Receptors, Purinergic P2X7, Saline Solution, Saphenous Vein, Signal Transduction, Swine, p38 Mitogen-Activated Protein KinasesAdded March 3, 2020
17 MeSH Terms