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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 22

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Discovering small molecules as Wnt inhibitors that promote heart regeneration and injury repair.
Xie S, Fu W, Yu G, Hu X, Lai KS, Peng X, Zhou Y, Zhu X, Christov P, Sawyer L, Ni TT, Sulikowski GA, Yang Z, Lee E, Zeng C, Wang WE, Zhong TP
(2020) J Mol Cell Biol 12: 42-54
MeSH Terms: Animals, Animals, Genetically Modified, Cell Differentiation, Cell Line, Cell Proliferation, Disease Models, Animal, Heart Injuries, Male, Mice, Mice, Inbred C57BL, Mouse Embryonic Stem Cells, Myocardial Infarction, Myocytes, Cardiac, Regenerative Medicine, Signal Transduction, Small Molecule Libraries, Wnt Proteins, Wnt Signaling Pathway, Wound Healing, Zebrafish, Zebrafish Proteins, beta Catenin
Added April 10, 2019
0 Communities
1 Members
0 Resources
22 MeSH Terms
Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators.
Owens P, Pickup MW, Novitskiy SV, Chytil A, Gorska AE, Aakre ME, West J, Moses HL
(2012) Proc Natl Acad Sci U S A 109: 2814-9
MeSH Terms: Animals, Antigens, Polyomavirus Transforming, Bone Morphogenetic Protein Receptors, Type II, Cell Movement, Cell Proliferation, Chemokines, Disease Progression, Female, Humans, Inflammation, Mammary Glands, Animal, Mammary Neoplasms, Animal, Mammary Tumor Virus, Mouse, Mice, Myeloid Cells, Neoplasm Invasiveness, Neoplasm Metastasis, Neovascularization, Pathologic, Paracrine Communication, Signal Transduction, Tumor Microenvironment
Added March 7, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
ErbB3 ablation impairs PI3K/Akt-dependent mammary tumorigenesis.
Cook RS, Garrett JT, Sánchez V, Stanford JC, Young C, Chakrabarty A, Rinehart C, Zhang Y, Wu Y, Greenberger L, Horak ID, Arteaga CL
(2011) Cancer Res 71: 3941-51
MeSH Terms: Animals, Breast Neoplasms, Cell Growth Processes, Cell Line, Tumor, Cell Transformation, Neoplastic, Disease Models, Animal, Female, Humans, Mammary Glands, Animal, Mammary Neoplasms, Experimental, Mammary Tumor Virus, Mouse, Mice, Mice, Transgenic, Oligonucleotides, Antisense, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Receptor, ErbB-3, Signal Transduction
Added March 5, 2014
1 Communities
2 Members
0 Resources
18 MeSH Terms
Loss of one Tgfbr2 allele in fibroblasts promotes metastasis in MMTV: polyoma middle T transgenic and transplant mouse models of mammary tumor progression.
Fang WB, Jokar I, Chytil A, Moses HL, Abel T, Cheng N
(2011) Clin Exp Metastasis 28: 351-66
MeSH Terms: Alleles, Animals, Antigens, Polyomavirus Transforming, Disease Models, Animal, Disease Progression, Female, Fibroblasts, Male, Mammary Neoplasms, Animal, Mammary Tumor Virus, Mouse, Mice, Mice, Nude, Mice, Transgenic, Neoplasm Metastasis, Protein Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Tumor Cells, Cultured
Added March 10, 2014
0 Communities
2 Members
0 Resources
18 MeSH Terms
Rapid extravasation and establishment of breast cancer micrometastases in the liver microenvironment.
Martin MD, Kremers GJ, Short KW, Rocheleau JV, Xu L, Piston DW, Matrisian LM, Gorden DL
(2010) Mol Cancer Res 8: 1319-27
MeSH Terms: Animals, Cell Line, Tumor, Cell Movement, Disease Models, Animal, Female, Liver Neoplasms, Experimental, Lung Neoplasms, Mammary Neoplasms, Experimental, Mammary Tumor Virus, Mouse, Mice, Retroviridae Infections, Tumor Microenvironment, Tumor Virus Infections
Added December 5, 2013
2 Communities
2 Members
0 Resources
13 MeSH Terms
Mammary tumors initiated by constitutive Cdk2 activation contain an invasive basal-like component.
Corsino PE, Davis BJ, Nørgaard PH, Parker NN, Law M, Dunn W, Law BK
(2008) Neoplasia 10: 1240-52
MeSH Terms: Animals, Breast Neoplasms, Cadherins, Catenins, Cell Adhesion Molecules, Cell Line, Tumor, Cyclin D1, Cyclin-Dependent Kinase 2, Female, Humans, Immunoblotting, Immunohistochemistry, Intermediate Filament Proteins, Mammary Neoplasms, Experimental, Mammary Tumor Virus, Mouse, Metalloproteins, Mice, Mice, Transgenic, Microscopy, Fluorescence, Neoplasm Invasiveness, Nerve Tissue Proteins, Nestin, Phosphoproteins, Protein Transport, Stress Fibers, Zyxin, beta Catenin
Added April 24, 2015
1 Communities
0 Members
0 Resources
27 MeSH Terms
Establishment and quantitative imaging of a 3D lung organotypic model of mammary tumor outgrowth.
Martin MD, Fingleton B, Lynch CC, Wells S, McIntyre JO, Piston DW, Matrisian LM
(2008) Clin Exp Metastasis 25: 877-85
MeSH Terms: Animals, Coculture Techniques, Diagnostic Imaging, Disease Models, Animal, Disease Progression, Female, Flow Cytometry, Green Fluorescent Proteins, Imaging, Three-Dimensional, Immunoenzyme Techniques, Lung Neoplasms, Mammary Neoplasms, Experimental, Mammary Tumor Virus, Mouse, Mice, Mice, Inbred C57BL, Mice, Nude, Mice, Transgenic, Microscopy, Confocal, Organ Culture Techniques, Tumor Cells, Cultured
Added January 17, 2014
1 Communities
4 Members
0 Resources
20 MeSH Terms
Effects of BRCA1 transgene expression on murine mammary gland development and mutagen-induced mammary neoplasia.
Hoshino A, Yee CJ, Campbell M, Woltjer RL, Townsend RL, van der Meer R, Shyr Y, Holt JT, Moses HL, Jensen RA
(2007) Int J Biol Sci 3: 281-91
MeSH Terms: 9,10-Dimethyl-1,2-benzanthracene, Animals, BRCA1 Protein, Carcinogens, Female, Gene Expression, Gene Transfer Techniques, Genes, BRCA1, Mammary Glands, Animal, Mammary Neoplasms, Experimental, Mammary Tumor Virus, Mouse, Mice, Mice, Inbred Strains, Mice, Transgenic, Pregnancy
Added February 17, 2014
1 Communities
1 Members
0 Resources
15 MeSH Terms
Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.
Biswas S, Guix M, Rinehart C, Dugger TC, Chytil A, Moses HL, Freeman ML, Arteaga CL
(2007) J Clin Invest 117: 1305-13
MeSH Terms: Animals, Antibodies, Blocking, Antigens, Polyomavirus Transforming, Cell Line, Tumor, Female, Humans, Lung Neoplasms, Mammary Neoplasms, Experimental, Mammary Tumor Virus, Mouse, Mice, Mice, Transgenic, Neoplasms, Radiation-Induced, Neoplastic Cells, Circulating, Retroviridae Infections, Signal Transduction, Transforming Growth Factor beta, Tumor Virus Infections
Added February 17, 2014
0 Communities
3 Members
0 Resources
17 MeSH Terms
Tumors initiated by constitutive Cdk2 activation exhibit transforming growth factor beta resistance and acquire paracrine mitogenic stimulation during progression.
Corsino P, Davis B, Law M, Chytil A, Forrester E, Nørgaard P, Teoh N, Law B
(2007) Cancer Res 67: 3135-44
MeSH Terms: Animals, Cyclin D1, Cyclin-Dependent Kinase 2, Disease Progression, Enzyme Activation, Female, Fibroblasts, Hepatocyte Growth Factor, Hyperplasia, Mammary Glands, Animal, Mammary Neoplasms, Experimental, Mammary Tumor Virus, Mouse, Mice, Mice, Transgenic, Promoter Regions, Genetic, Recombinant Fusion Proteins, Retinoblastoma Protein, Retinoblastoma-Like Protein p130, Transforming Growth Factor beta
Added August 13, 2010
1 Communities
0 Members
0 Resources
19 MeSH Terms