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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 390

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A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for in pancreas development.
Osipovich AB, Dudek KD, Greenfest-Allen E, Cartailler JP, Manduchi E, Potter Case L, Choi E, Chapman AG, Clayton HW, Gu G, Stoeckert CJ, Magnuson MA
(2021) Development 148:
MeSH Terms: Animals, Cadherins, Cell Differentiation, Cell Lineage, Gene Expression Regulation, Developmental, Homeodomain Proteins, Insulin, Islets of Langerhans, Mice, Organogenesis, Pancreas
Added March 15, 2021
2 Communities
2 Members
0 Resources
11 MeSH Terms
Molecular and functional profiling of human islets: from heterogeneity to human phenotypes.
Arrojo E Drigo R, Roy B, MacDonald PE
(2020) Diabetologia 63: 2095-2101
MeSH Terms: Calcium, Genotype, Humans, Insulin Secretion, Insulin-Secreting Cells, Islets of Langerhans, Phenotype, Single-Cell Analysis, Transcriptome
Added April 14, 2021
0 Communities
1 Members
0 Resources
9 MeSH Terms
Lactate activation of α-cell K channels inhibits glucagon secretion by hyperpolarizing the membrane potential and reducing Ca entry.
Zaborska KE, Dadi PK, Dickerson MT, Nakhe AY, Thorson AS, Schaub CM, Graff SM, Stanley JE, Kondapavuluru RS, Denton JS, Jacobson DA
(2020) Mol Metab 42: 101056
MeSH Terms: Animals, Calcium, Cell Line, Cell Membrane, Glucagon, Glucagon-Secreting Cells, Glucose, Humans, Islets of Langerhans, KATP Channels, Lactic Acid, Male, Membrane Potentials, Mice, Mice, Inbred C57BL, Mice, Transgenic, Pancreas, Primary Cell Culture, Pyruvic Acid
Added June 14, 2021
0 Communities
1 Members
0 Resources
19 MeSH Terms
Dapagliflozin Does Not Directly Affect Human α or β Cells.
Dai C, Walker JT, Shostak A, Bouchi Y, Poffenberger G, Hart NJ, Jacobson DA, Calcutt MW, Bottino R, Greiner DL, Shultz LD, McGuinness OP, Dean ED, Powers AC
(2020) Endocrinology 161:
MeSH Terms: Adolescent, Adult, Animals, Benzhydryl Compounds, Cells, Cultured, Female, Glucagon, Glucagon-Secreting Cells, Glucosides, Heterografts, Humans, Insulin, Insulin Secretion, Insulin-Secreting Cells, Islets of Langerhans, Male, Mice, Mice, Inbred NOD, Mice, Transgenic, Middle Aged, Signal Transduction, Species Specificity, Young Adult
Added June 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Ins1-Cre and Ins1-CreER Gene Replacement Alleles Are Susceptible To Silencing By DNA Hypermethylation.
Mosleh E, Ou K, Haemmerle MW, Tembo T, Yuhas A, Carboneau BA, Townsend SE, Bosma KJ, Gannon M, O'Brien RM, Stoffers DA, Golson ML
(2020) Endocrinology 161:
MeSH Terms: Alleles, Animals, Cells, Cultured, DNA Methylation, Female, Gene Silencing, HEK293 Cells, Humans, Insulin, Insulin-Secreting Cells, Integrases, Islets of Langerhans, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Organ Specificity, Recombination, Genetic
Added May 12, 2020
1 Communities
0 Members
0 Resources
18 MeSH Terms
Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable.
Dai C, Walker JT, Shostak A, Padgett A, Spears E, Wisniewski S, Poffenberger G, Aramandla R, Dean ED, Prasad N, Levy SE, Greiner DL, Shultz LD, Bottino R, Powers AC
(2020) JCI Insight 5:
MeSH Terms: Animals, Calcineurin, Diabetes Mellitus, Graft Rejection, Humans, Immunosuppressive Agents, Insulin, Insulin-Secreting Cells, Islets of Langerhans, Islets of Langerhans Transplantation, Male, Mice, Signal Transduction, Sirolimus, TOR Serine-Threonine Kinases, Tacrolimus
Added March 29, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
Lipid Droplet Accumulation in Human Pancreatic Islets Is Dependent On Both Donor Age and Health.
Tong X, Dai C, Walker JT, Nair GG, Kennedy A, Carr RM, Hebrok M, Powers AC, Stein R
(2020) Diabetes 69: 342-354
MeSH Terms: Acinar Cells, Adolescent, Adult, Age Factors, Aged, Animals, Child, Child, Preschool, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 2, Embryonic Stem Cells, Female, Glucagon-Secreting Cells, Humans, Infant, Insulin-Secreting Cells, Islets of Langerhans, Islets of Langerhans Transplantation, Lipid Droplets, Male, Mice, Microscopy, Electron, Microscopy, Fluorescence, Middle Aged, Rats, Tissue Donors, Young Adult
Added March 29, 2020
0 Communities
1 Members
0 Resources
27 MeSH Terms
Ion Channels of the Islets in Type 2 Diabetes.
Jacobson DA, Shyng SL
(2020) J Mol Biol 432: 1326-1346
MeSH Terms: Animals, Calcium, Calcium Channels, Calcium Signaling, Diabetes Mellitus, Type 2, Glucose, Humans, Hyperglycemia, Insulin, Insulin Secretion, Insulin-Secreting Cells, Islets of Langerhans
Added June 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Structural basis for delta cell paracrine regulation in pancreatic islets.
Arrojo E Drigo R, Jacob S, García-Prieto CF, Zheng X, Fukuda M, Nhu HTT, Stelmashenko O, Peçanha FLM, Rodriguez-Diaz R, Bushong E, Deerinck T, Phan S, Ali Y, Leibiger I, Chua M, Boudier T, Song SH, Graf M, Augustine GJ, Ellisman MH, Berggren PO
(2019) Nat Commun 10: 3700
MeSH Terms: Animals, Blood Glucose, Humans, Insulin-Like Growth Factor I, Insulin-Secreting Cells, Intravital Microscopy, Islets of Langerhans, Mice, Mice, Transgenic, Microscopy, Electron, Optical Imaging, Optogenetics, Paracrine Communication, Prediabetic State, Pseudopodia, Somatostatin-Secreting Cells, Vascular Endothelial Growth Factor A
Added April 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib.
Wilson CS, Spaeth JM, Karp J, Stocks BT, Hoopes EM, Stein RW, Moore DJ
(2019) JCI Insight 5:
MeSH Terms: Animals, Autoimmunity, B-Lymphocytes, Cell Proliferation, Diabetes Mellitus, Type 1, Disease Models, Animal, Homeodomain Proteins, Hyperglycemia, Imatinib Mesylate, Insulin, Insulin-Secreting Cells, Islets of Langerhans, Maf Transcription Factors, Large, Mice, Mice, Inbred C57BL, Mice, Inbred NOD, Mice, Knockout
Added April 10, 2019
0 Communities
1 Members
0 Resources
17 MeSH Terms