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Results: 1 to 7 of 7

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Structural and Molecular Determinants of Membrane Binding by the HIV-1 Matrix Protein.
Mercredi PY, Bucca N, Loeliger B, Gaines CR, Mehta M, Bhargava P, Tedbury PR, Charlier L, Floquet N, Muriaux D, Favard C, Sanders CR, Freed EO, Marchant J, Summers MF
(2016) J Mol Biol 428: 1637-55
MeSH Terms: Cell Membrane, HIV-1, Lipids, Liposomes, Magnetic Resonance Spectroscopy, Membrane Microdomains, Phosphatidylinositol 4,5-Diphosphate, Phosphatidylserines, Protein Binding, Protein Structure, Tertiary, gag Gene Products, Human Immunodeficiency Virus
Added November 21, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Protease cleavage leads to formation of mature trimer interface in HIV-1 capsid.
Meng X, Zhao G, Yufenyuy E, Ke D, Ning J, Delucia M, Ahn J, Gronenborn AM, Aiken C, Zhang P
(2012) PLoS Pathog 8: e1002886
MeSH Terms: Capsid, Cryoelectron Microscopy, HIV Protease, HIV-1, Protein Multimerization, Proteolysis, gag Gene Products, Human Immunodeficiency Virus
Added February 19, 2015
0 Communities
1 Members
0 Resources
7 MeSH Terms
APOBEC3G complexes decrease human immunodeficiency virus type 1 production.
Martin KL, Johnson M, D'Aquila RT
(2011) J Virol 85: 9314-26
MeSH Terms: APOBEC-3G Deaminase, Cell Line, Cytidine Deaminase, Epithelial Cells, HIV-1, Humans, Mutant Proteins, T-Lymphocytes, Virus Replication, gag Gene Products, Human Immunodeficiency Virus, vif Gene Products, Human Immunodeficiency Virus
Added December 5, 2013
1 Communities
0 Members
0 Resources
11 MeSH Terms
Structure of the HIV-1 full-length capsid protein in a conformationally trapped unassembled state induced by small-molecule binding.
Du S, Betts L, Yang R, Shi H, Concel J, Ahn J, Aiken C, Zhang P, Yeh JI
(2011) J Mol Biol 406: 371-86
MeSH Terms: Binding Sites, Capsid Proteins, Crystallography, X-Ray, HIV Infections, HIV-1, Humans, Models, Molecular, Molecular Structure, Protein Binding, Protein Conformation, Protein Structure, Tertiary, Virus Replication, gag Gene Products, Human Immunodeficiency Virus
Added February 19, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Pseudovirion particles bearing native HIV envelope trimers facilitate a novel method for generating human neutralizing monoclonal antibodies against HIV.
Hicar MD, Chen X, Briney B, Hammonds J, Wang JJ, Kalams S, Spearman PW, Crowe JE
(2010) J Acquir Immune Defic Syndr 54: 223-35
MeSH Terms: AIDS Vaccines, Amino Acid Sequence, Antibodies, Monoclonal, Antibody Specificity, Antigens, CD19, B-Lymphocytes, Cells, Cultured, Gene Expression Regulation, Green Fluorescent Proteins, HIV, Humans, Hybridomas, Immunoglobulins, Molecular Sequence Data, Protein Multimerization, Virion, env Gene Products, Human Immunodeficiency Virus, gag Gene Products, Human Immunodeficiency Virus
Added August 6, 2012
0 Communities
1 Members
0 Resources
18 MeSH Terms
Nef enhances HIV-1 infectivity via association with the virus assembly complex.
Qi M, Aiken C
(2008) Virology 373: 287-97
MeSH Terms: Amino Acid Substitution, Base Sequence, Binding Sites, Cell Line, Cyclophilin A, Cyclosporine, DNA Primers, Genes, nef, HIV-1, HeLa Cells, Humans, Multiprotein Complexes, Mutation, Plasmids, Recombinant Fusion Proteins, Virulence, Virus Assembly, gag Gene Products, Human Immunodeficiency Virus, nef Gene Products, Human Immunodeficiency Virus
Added February 19, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication.
Schneidewind A, Brockman MA, Yang R, Adam RI, Li B, Le Gall S, Rinaldo CR, Craggs SL, Allgaier RL, Power KA, Kuntzen T, Tung CS, LaBute MX, Mueller SM, Harrer T, McMichael AJ, Goulder PJ, Aiken C, Brander C, Kelleher AD, Allen TM
(2007) J Virol 81: 12382-93
MeSH Terms: Amino Acid Sequence, Capsid, Cyclosporine, HIV Infections, HIV-1, HLA-B27 Antigen, Humans, Immunodominant Epitopes, Molecular Sequence Data, Mutation, T-Lymphocytes, Cytotoxic, Virus Replication, gag Gene Products, Human Immunodeficiency Virus
Added February 19, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms