The outcome of allogeneic hematopoietic cell transplantation for children with FMS-like tyrosine kinase 3 internal tandem duplication-positive acute myelogenous leukemia.
Schechter T, Gassas A, Chen H, Pollard J, Meshinchi S, Zaidman I, Hitzler J, Abdelhaleem M, Ho R, Domm J, Woolfrey A, Frangoul H
(2015) Biol Blood Marrow Transplant 21
: 172-5MeSH Terms: Adolescent, Child, Child, Preschool, Chromosome Duplication, Female, Graft vs Host Disease, Hematopoietic Stem Cell Transplantation, Humans, Immunosuppressive Agents, Leukemia, Myeloid, Acute, Male, Myeloablative Agonists, Recurrence, Retrospective Studies, Siblings, Survival Analysis, Transplantation Conditioning, Transplantation, Homologous, Treatment Outcome, Unrelated Donors, Whole-Body Irradiation, Young Adult, fms-Like Tyrosine Kinase 3Added February 25, 2015
23 MeSH Terms
Allo-SCT for high-risk AML-CR1 in the molecular era: impact of FLT3/ITD outweighs the conventional markers.
Sengsayadeth SM, Jagasia M, Engelhardt BG, Kassim A, Strickland SA, Goodman S, Lucid C, Vnencak-Jones CL, Greer JP, Savani BN
(2012) Bone Marrow Transplant 47
: 1535-7MeSH Terms: Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, Combined Modality Therapy, Female, Humans, Leukemia, Myeloid, Acute, Male, Middle Aged, Mutation, Prognosis, Stem Cell Transplantation, Survival Analysis, Tandem Repeat Sequences, Transplantation, Homologous, Treatment Outcome, Young Adult, fms-Like Tyrosine Kinase 3Added March 5, 2014
20 MeSH Terms
Cell-intrinsic role for IFN-α-STAT1 signals in regulating murine Peyer patch plasmacytoid dendritic cells and conditioning an inflammatory response.
Li HS, Gelbard A, Martinez GJ, Esashi E, Zhang H, Nguyen-Jackson H, Liu YJ, Overwijk WW, Watowich SS
(2011) Blood 118
: 3879-89MeSH Terms: Animals, Cell Differentiation, Dendritic Cells, Interferon-alpha, Mice, Mice, Inbred C57BL, Peyer's Patches, STAT1 Transcription Factor, Stem Cells, Th17 Cells, fms-Like Tyrosine Kinase 3Added April 11, 2014
11 MeSH Terms
Prophylactic treatment with fms-like tyrosine kinase-3 ligand after burn injury enhances global immune responses to infection.
Bohannon J, Cui W, Cox R, Przkora R, Sherwood E, Toliver-Kinsky T
(2008) J Immunol 180
: 3038-48MeSH Terms: Adjuvants, Immunologic, Animals, Burns, Cell Differentiation, Cell Movement, Cell Proliferation, Dendritic Cells, Langerhans Cells, Ligands, Lymph Nodes, Lymphocyte Activation, Male, Membrane Proteins, Mice, Mice, Inbred BALB C, Pseudomonas Infections, Spleen, fms-Like Tyrosine Kinase 3Added October 18, 2015
18 MeSH Terms
Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53.
Irish JM, Anensen N, Hovland R, Skavland J, Børresen-Dale AL, Bruserud O, Nolan GP, Gjertsen BT
(2007) Blood 109
: 2589-96MeSH Terms: Cells, Cultured, DNA Damage, Electrophoresis, Gel, Two-Dimensional, Gene Expression, Gene Expression Profiling, Gene Expression Regulation, Leukemic, Humans, Leukemia, Myeloid, Acute, Mutation, Phosphorylation, Protein Isoforms, Proto-Oncogene Proteins c-bcl-2, Signal Transduction, Tumor Suppressor Protein p53, Tyrosine, fms-Like Tyrosine Kinase 3Added February 15, 2013
16 MeSH Terms
Enhancement of dendritic cell production by fms-like tyrosine kinase-3 ligand increases the resistance of mice to a burn wound infection.
Toliver-Kinsky TE, Cui W, Murphey ED, Lin C, Sherwood ER
(2005) J Immunol 174
: 404-10MeSH Terms: Adoptive Transfer, Animals, Burns, Cell Count, Dendritic Cells, Flow Cytometry, Humans, Ligands, Mice, Proto-Oncogene Proteins, Pseudomonas Infections, Receptor Protein-Tyrosine Kinases, Spleen, Wound Infection, fms-Like Tyrosine Kinase 3Added October 18, 2015
15 MeSH Terms
Single cell profiling of potentiated phospho-protein networks in cancer cells.
Irish JM, Hovland R, Krutzik PO, Perez OD, Bruserud Ø, Gjertsen BT, Nolan GP
(2004) Cell 118
: 217-28MeSH Terms: Antineoplastic Agents, Carcinogens, Environmental, Cell Transformation, Neoplastic, DNA-Binding Proteins, Flow Cytometry, Fluorescent Antibody Technique, Gene Expression Regulation, Neoplastic, Humans, Leukemia, Myeloid, Acute, MAP Kinase Signaling System, Mutation, Phosphoproteins, Phosphorylation, Proto-Oncogene Proteins, Receptor Protein-Tyrosine Kinases, STAT1 Transcription Factor, Signal Transduction, Trans-Activators, fms-Like Tyrosine Kinase 3, ras ProteinsAdded February 15, 2013
20 MeSH Terms
Differentiation of NK1.1+, Ly49+ NK cells from flt3+ multipotent marrow progenitor cells.
Williams NS, Klem J, Puzanov IJ, Sivakumar PV, Bennett M, Kumar V
(1999) J Immunol 163
: 2648-56MeSH Terms: Animals, Antigens, Antigens, Ly, Antigens, Surface, Bone Marrow Cells, Cell Differentiation, Cell Lineage, Cells, Cultured, Coculture Techniques, Hematopoietic Stem Cells, Interleukin-15, Killer Cells, Natural, Lectins, C-Type, Ligands, Lymphocyte Subsets, Membrane Glycoproteins, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Inbred DBA, Mice, SCID, NK Cell Lectin-Like Receptor Subfamily B, Proteins, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-kit, Receptor Protein-Tyrosine Kinases, Receptors, NK Cell Lectin-Like, Stromal Cells, fms-Like Tyrosine Kinase 3Added March 5, 2014
29 MeSH Terms