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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 32

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Non-visual arrestins regulate the focal adhesion formation via small GTPases RhoA and Rac1 independently of GPCRs.
Cleghorn WM, Bulus N, Kook S, Gurevich VV, Zent R, Gurevich EV
(2018) Cell Signal 42: 259-269
MeSH Terms: Actin Cytoskeleton, Animals, Cell Adhesion, Cell Line, Cell Movement, Fibroblasts, Focal Adhesions, Gene Expression Regulation, Mice, Neuropeptides, Receptors, G-Protein-Coupled, Signal Transduction, beta-Arrestin 1, beta-Arrestin 2, cdc42 GTP-Binding Protein, rac1 GTP-Binding Protein, rho GTP-Binding Proteins, rhoA GTP-Binding Protein
Added March 14, 2018
0 Communities
1 Members
0 Resources
18 MeSH Terms
Cdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development.
Elias BC, Das A, Parekh DV, Mernaugh G, Adams R, Yang Z, Brakebusch C, Pozzi A, Marciano DK, Carroll TJ, Zent R
(2015) J Cell Sci 128: 4293-305
MeSH Terms: Animals, Cell Polarity, Cytoskeleton, Epithelial Cells, Kidney Tubules, Mice, cdc42 GTP-Binding Protein
Added February 4, 2016
1 Communities
1 Members
1 Resources
7 MeSH Terms
Type III TGFβ receptor and Src direct hyaluronan-mediated invasive cell motility.
Allison P, Espiritu D, Barnett JV, Camenisch TD
(2015) Cell Signal 27: 453-9
MeSH Terms: Actin Cytoskeleton, Amino Acid Substitution, Animals, Arrestin, Cell Movement, Cells, Cultured, Epithelial-Mesenchymal Transition, Hyaluronic Acid, Mice, Neuropeptides, Pericardium, Protein Binding, Proteoglycans, RNA Interference, RNA, Small Interfering, Receptors, Transforming Growth Factor beta, cdc42 GTP-Binding Protein, rac1 GTP-Binding Protein, rho GTP-Binding Proteins, rhoA GTP-Binding Protein, src-Family Kinases
Added February 21, 2016
0 Communities
1 Members
0 Resources
21 MeSH Terms
CD148 tyrosine phosphatase promotes cadherin cell adhesion.
Takahashi K, Matafonov A, Sumarriva K, Ito H, Lauhan C, Zemel D, Tsuboi N, Chen J, Reynolds A, Takahashi T
(2014) PLoS One 9: e112753
MeSH Terms: Cadherins, Cell Adhesion, Cell Line, Drosophila Proteins, Humans, Phosphorylation, Receptor-Like Protein Tyrosine Phosphatases, Class 3, Tyrosine, beta Catenin, cdc42 GTP-Binding Protein, rac GTP-Binding Proteins, rhoA GTP-Binding Protein
Added February 12, 2015
1 Communities
2 Members
0 Resources
12 MeSH Terms
Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesis.
Baschieri F, Confalonieri S, Bertalot G, Di Fiore PP, Dietmaier W, Leist M, Crespo P, Macara IG, Farhan H
(2014) Nat Commun 5: 4839
MeSH Terms: Antigens, CD, Autoantigens, Cadherins, Carcinogenesis, Cell Line, Tumor, Cell Polarity, Gene Expression Regulation, Neoplastic, Gene Silencing, Humans, MAP Kinase Signaling System, MCF-7 Cells, Membrane Proteins, Mitogen-Activated Protein Kinase 3, Rho Guanine Nucleotide Exchange Factors, Signal Transduction, cdc42 GTP-Binding Protein, ras Guanine Nucleotide Exchange Factors, ras-GRF1
Added April 10, 2018
0 Communities
1 Members
0 Resources
18 MeSH Terms
Activation of Rac by Asef2 promotes myosin II-dependent contractility to inhibit cell migration on type I collagen.
Jean L, Majumdar D, Shi M, Hinkle LE, Diggins NL, Ao M, Broussard JA, Evans JC, Choma DP, Webb DJ
(2013) J Cell Sci 126: 5585-97
MeSH Terms: Cell Adhesion, Cell Line, Tumor, Cell Movement, Collagen Type I, Guanine Nucleotide Exchange Factors, Humans, Integrin beta1, Myosin Type II, cdc42 GTP-Binding Protein, rac GTP-Binding Proteins
Added May 20, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Cdc42 coordinates proliferation, polarity, migration, and differentiation of small intestinal epithelial cells in mice.
Melendez J, Liu M, Sampson L, Akunuru S, Han X, Vallance J, Witte D, Shroyer N, Zheng Y
(2013) Gastroenterology 145: 808-19
MeSH Terms: Animals, Cell Differentiation, Cell Movement, Cell Polarity, Cell Proliferation, Intestinal Mucosa, Intestine, Small, Mice, cdc42 GTP-Binding Protein
Added March 19, 2017
0 Communities
1 Members
0 Resources
9 MeSH Terms
Cdc42 promotes host defenses against fatal infection.
Lee K, Boyd KL, Parekh DV, Kehl-Fie TE, Baldwin HS, Brakebusch C, Skaar EP, Boothby M, Zent R
(2013) Infect Immun 81: 2714-23
MeSH Terms: Animals, Chemotaxis, Leukocyte, Fibroblasts, Flow Cytometry, Immunity, Innate, Immunoblotting, Infections, Mice, Mice, Inbred C57BL, Mice, Transgenic, Neutrophils, cdc42 GTP-Binding Protein
Added December 10, 2013
1 Communities
4 Members
0 Resources
12 MeSH Terms
CDC42 is required for tissue lamination and cell survival in the mouse retina.
Heynen SR, Meneau I, Caprara C, Samardzija M, Imsand C, Levine EM, Grimm C
(2013) PLoS One 8: e53806
MeSH Terms: Animals, Animals, Newborn, Cell Survival, Embryo, Mammalian, Gene Expression, Gene Expression Profiling, Mice, Mice, Knockout, Microvessels, Morphogenesis, Neuroglia, Neurons, Retina, cdc42 GTP-Binding Protein
Added November 2, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Modelling cell polarization driven by synthetic spatially graded Rac activation.
Holmes WR, Lin B, Levchenko A, Edelstein-Keshet L
(2012) PLoS Comput Biol 8: e1002366
MeSH Terms: Cell Membrane, Cell Polarity, Cell Shape, Computational Biology, Computer Simulation, Cytosol, Enzyme Activation, Feedback, Physiological, HeLa Cells, Humans, Models, Biological, Phosphatidylinositols, Receptor Cross-Talk, cdc42 GTP-Binding Protein, rac GTP-Binding Proteins, rho GTP-Binding Proteins
Added February 26, 2016
0 Communities
1 Members
0 Resources
16 MeSH Terms