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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 5 of 5

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Treatment-Induced Tumor Cell Apoptosis and Secondary Necrosis Drive Tumor Progression in the Residual Tumor Microenvironment through MerTK and IDO1.
Werfel TA, Elion DL, Rahman B, Hicks DJ, Sanchez V, Gonzales-Ericsson PI, Nixon MJ, James JL, Balko JM, Scherle PA, Koblish HK, Cook RS
(2019) Cancer Res 79: 171-182
MeSH Terms: Animals, Antineoplastic Agents, Apoptosis, Female, Indoleamine-Pyrrole 2,3,-Dioxygenase, Inflammation, Lapatinib, Lung Neoplasms, Macrophages, Mammary Neoplasms, Experimental, Mice, Necrosis, Phagocytosis, Receptor, ErbB-2, T-Lymphocytes, Regulatory, Tumor Microenvironment, c-Mer Tyrosine Kinase
Added April 15, 2019
0 Communities
1 Members
0 Resources
17 MeSH Terms
Diverse, Biologically Relevant, and Targetable Gene Rearrangements in Triple-Negative Breast Cancer and Other Malignancies.
Shaver TM, Lehmann BD, Beeler JS, Li CI, Li Z, Jin H, Stricker TP, Shyr Y, Pietenpol JA
(2016) Cancer Res 76: 4850-60
MeSH Terms: Algorithms, Cell Line, Tumor, Female, Gene Expression Profiling, Gene Rearrangement, Humans, Immunoblotting, Neoplasms, Oncogene Proteins, Fusion, Polymerase Chain Reaction, Proto-Oncogene Proteins, Receptor Protein-Tyrosine Kinases, Triple Negative Breast Neoplasms, c-Mer Tyrosine Kinase
Added April 9, 2017
1 Communities
1 Members
0 Resources
14 MeSH Terms
Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution.
Stanford JC, Young C, Hicks D, Owens P, Williams A, Vaught DB, Morrison MM, Lim J, Williams M, Brantley-Sieders DM, Balko JM, Tonetti D, Earp HS, Cook RS
(2014) J Clin Invest 124: 4737-52
MeSH Terms: Animals, Apoptosis, Coculture Techniques, Cytokines, Female, Gene Expression, Gene Expression Regulation, Neoplastic, Humans, Lung Neoplasms, MCF-7 Cells, Male, Mammary Glands, Animal, Mammary Neoplasms, Experimental, Mice, Transgenic, Neoplasm Transplantation, Phagocytosis, Postpartum Period, Proto-Oncogene Proteins, Receptor Protein-Tyrosine Kinases, Signal Transduction, Tumor Burden, Up-Regulation, c-Mer Tyrosine Kinase
Added February 12, 2015
1 Communities
2 Members
0 Resources
23 MeSH Terms
MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis.
Cook RS, Jacobsen KM, Wofford AM, DeRyckere D, Stanford J, Prieto AL, Redente E, Sandahl M, Hunter DM, Strunk KE, Graham DK, Earp HS
(2013) J Clin Invest 123: 3231-42
MeSH Terms: Animals, CD8-Positive T-Lymphocytes, Colonic Neoplasms, Cytokines, Disease Resistance, Female, Gene Expression Regulation, Neoplastic, Leukocytes, Male, Mammary Neoplasms, Experimental, Melanoma, Experimental, Mice, Mice, Inbred C57BL, Mice, Knockout, Neoplasm Transplantation, Proto-Oncogene Proteins, Receptor Protein-Tyrosine Kinases, Transcriptome, Tumor Burden, Tumor Microenvironment, c-Mer Tyrosine Kinase
Added March 7, 2014
1 Communities
1 Members
0 Resources
21 MeSH Terms
Epithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactation.
Sandahl M, Hunter DM, Strunk KE, Earp HS, Cook RS
(2010) BMC Dev Biol 10: 122
MeSH Terms: Animals, Apoptosis, Epithelial Cells, Female, Homeostasis, Lactation, Macrophages, Mammary Glands, Animal, Mice, Mice, Inbred C57BL, Mice, Transgenic, Phagocytosis, Polymerase Chain Reaction, Proto-Oncogene Proteins, Receptor Protein-Tyrosine Kinases, c-Mer Tyrosine Kinase
Added March 27, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms