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Results: 1 to 10 of 28

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Arrestins and G proteins in cellular signaling: The coin has two sides.
Gurevich VV, Gurevich EV
(2018) Sci Signal 11:
MeSH Terms: Arrestins, CRISPR-Cas Systems, Phosphorylation, RNA, Small Interfering, beta-Arrestins
Added March 18, 2020
0 Communities
1 Members
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MeSH Terms
Heterologous phosphorylation-induced formation of a stability lock permits regulation of inactive receptors by β-arrestins.
Tóth AD, Prokop S, Gyombolai P, Várnai P, Balla A, Gurevich VV, Hunyady L, Turu G
(2018) J Biol Chem 293: 876-892
MeSH Terms: Angiotensin II, Animals, COS Cells, Chlorocebus aethiops, HEK293 Cells, Humans, Immunoblotting, Microscopy, Confocal, Mitogen-Activated Protein Kinases, Phosphorylation, Receptors, G-Protein-Coupled, beta-Arrestins
Added March 14, 2018
0 Communities
1 Members
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12 MeSH Terms
A G Protein-biased Designer G Protein-coupled Receptor Useful for Studying the Physiological Relevance of Gq/11-dependent Signaling Pathways.
Hu J, Stern M, Gimenez LE, Wanka L, Zhu L, Rossi M, Meister J, Inoue A, Beck-Sickinger AG, Gurevich VV, Wess J
(2016) J Biol Chem 291: 7809-20
MeSH Terms: Animals, Arrestins, COS Cells, Calcium, Cells, Cultured, Chlorocebus aethiops, GTP-Binding Protein alpha Subunits, Gq-G11, Gene Knockdown Techniques, Glucose, HEK293 Cells, Hepatocytes, Humans, Mice, Inbred C57BL, Protein Interaction Mapping, Protein Interaction Maps, Receptors, G-Protein-Coupled, Signal Transduction, beta-Arrestins
Added February 15, 2016
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1 Members
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18 MeSH Terms
Development of an MRI biomarker sensitive to tetrameric visual arrestin 1 and its reduction via light-evoked translocation in vivo.
Berkowitz BA, Gorgis J, Patel A, Baameur F, Gurevich VV, Craft CM, Kefalov VJ, Roberts R
(2015) FASEB J 29: 554-64
MeSH Terms: Animals, Arrestins, Biomarkers, Body Weight, Colloids, Diabetes Mellitus, Experimental, Diabetic Retinopathy, Ferric Compounds, Immunohistochemistry, Light, Light Signal Transduction, Magnetic Resonance Imaging, Male, Manganese, Mice, Mice, Inbred C57BL, Nanoparticles, Protein Transport, Retina, Retinal Rod Photoreceptor Cells, Rod Cell Outer Segment, Signal Transduction, beta-Arrestin 1, beta-Arrestins
Added February 12, 2015
0 Communities
1 Members
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24 MeSH Terms
Arrestin makes T cells stop and become active.
Gurevich VV, Gurevich EV
(2014) EMBO J 33: 531-3
MeSH Terms: Animals, Arrestins, Gene Expression Regulation, Humans, Immunological Synapses, Models, Immunological, Receptors, Antigen, T-Cell, Signal Transduction, beta-Arrestin 1, beta-Arrestins
Added February 12, 2015
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1 Members
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10 MeSH Terms
Arrestins in apoptosis.
Kook S, Gurevich VV, Gurevich EV
(2014) Handb Exp Pharmacol 219: 309-39
MeSH Terms: Animals, Apoptosis, Arrestins, Caspases, DNA Damage, Endoplasmic Reticulum Stress, Humans, MAP Kinase Signaling System, Signal Transduction, Tumor Suppressor Protein p53, beta-Arrestins
Added February 12, 2015
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1 Members
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11 MeSH Terms
Visual arrestin interaction with clathrin adaptor AP-2 regulates photoreceptor survival in the vertebrate retina.
Moaven H, Koike Y, Jao CC, Gurevich VV, Langen R, Chen J
(2013) Proc Natl Acad Sci U S A 110: 9463-8
MeSH Terms: Adaptor Protein Complex 2, Analysis of Variance, Animals, Arrestins, Blotting, Western, Cell Survival, Electron Spin Resonance Spectroscopy, Electroretinography, GTP-Binding Proteins, Immunohistochemistry, Mice, Mice, Transgenic, Mutation, Missense, Photoreceptor Cells, Vertebrate, Retinal Degeneration, Rhodopsin, Signal Transduction, beta-Arrestin 1, beta-Arrestins
Added February 12, 2015
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19 MeSH Terms
Critical role of the central 139-loop in stability and binding selectivity of arrestin-1.
Vishnivetskiy SA, Baameur F, Findley KR, Gurevich VV
(2013) J Biol Chem 288: 11741-50
MeSH Terms: Amino Acid Substitution, Animals, Arrestins, Binding Sites, Cattle, Humans, Mice, Mutation, Missense, Protein Binding, Protein Stability, Protein Structure, Secondary, Rats, Rod Opsins, beta-Arrestins
Added December 10, 2013
0 Communities
1 Members
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14 MeSH Terms
Engineering visual arrestin-1 with special functional characteristics.
Vishnivetskiy SA, Chen Q, Palazzo MC, Brooks EK, Altenbach C, Iverson TM, Hubbell WL, Gurevich VV
(2013) J Biol Chem 288: 3394-405
MeSH Terms: Animals, Arrestins, Eye, HEK293 Cells, Humans, Mice, Models, Molecular, Mutant Proteins, Mutation, Phosphates, Protein Binding, Protein Engineering, Protein Stability, Protein Structure, Tertiary, Rhodopsin, Static Electricity, Temperature, beta-Arrestins
Added December 10, 2013
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1 Members
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18 MeSH Terms
The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activation.
Coffa S, Breitman M, Hanson SM, Callaway K, Kook S, Dalby KN, Gurevich VV
(2011) PLoS One 6: e28723
MeSH Terms: Animals, Arrestin, Arrestins, COS Cells, Cattle, Chlorocebus aethiops, Embryo, Mammalian, Enzyme Activation, Fibroblasts, HEK293 Cells, Humans, Ligands, MAP Kinase Kinase 1, Mice, Mice, Knockout, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Mutant Proteins, Phosphorylation, Protein Binding, Protein Conformation, Proto-Oncogene Proteins c-raf, Receptors, Adrenergic, beta-2, Structure-Activity Relationship, beta-Arrestins
Added December 10, 2013
0 Communities
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25 MeSH Terms