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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 13

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Increased Ripk1-mediated bone marrow necroptosis leads to myelodysplasia and bone marrow failure in mice.
Wagner PN, Shi Q, Salisbury-Ruf CT, Zou J, Savona MR, Fedoriw Y, Zinkel SS
(2019) Blood 133: 107-120
MeSH Terms: Animals, BH3 Interacting Domain Death Agonist Protein, Bone Marrow, Bone Marrow Diseases, Cells, Cultured, Cytokines, Hematopoietic Stem Cells, Inflammation, Mice, Mice, Inbred C57BL, Mice, Knockout, Myelodysplastic Syndromes, Necrosis, Receptor-Interacting Protein Serine-Threonine Kinases, bcl-2 Homologous Antagonist-Killer Protein
Added December 11, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics.
Sarosiek KA, Fraser C, Muthalagu N, Bhola PD, Chang W, McBrayer SK, Cantlon A, Fisch S, Golomb-Mello G, Ryan JA, Deng J, Jian B, Corbett C, Goldenberg M, Madsen JR, Liao R, Walsh D, Sedivy J, Murphy DJ, Carrasco DR, Robinson S, Moslehi J, Letai A
(2017) Cancer Cell 31: 142-156
MeSH Terms: Age Factors, Animals, Apoptosis, Doxorubicin, Humans, Mice, Mitochondria, Neoplasms, Organ Specificity, Proto-Oncogene Proteins c-myc, bcl-2 Homologous Antagonist-Killer Protein, bcl-2-Associated X Protein
Added March 26, 2017
0 Communities
1 Members
0 Resources
12 MeSH Terms
CRM1 protein-mediated regulation of nuclear clusterin (nCLU), an ionizing radiation-stimulated, Bax-dependent pro-death factor.
Leskov KS, Araki S, Lavik JP, Gomez JA, Gama V, Gonos ES, Trougakos IP, Matsuyama S, Boothman DA
(2011) J Biol Chem 286: 40083-90
MeSH Terms: Active Transport, Cell Nucleus, Animals, Antibiotics, Antineoplastic, Apoptosis, Cell Nucleus, Clusterin, Fatty Acids, Unsaturated, Gamma Rays, Humans, Karyopherins, Mice, Mice, Knockout, Protein Isoforms, Radiation Tolerance, Receptors, Cytoplasmic and Nuclear, bcl-2 Homologous Antagonist-Killer Protein, bcl-2-Associated X Protein
Added October 26, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
A role for proapoptotic Bax and Bak in T-cell differentiation and transformation.
Biswas S, Shi Q, Matise L, Cleveland S, Dave U, Zinkel S
(2010) Blood 116: 5237-46
MeSH Terms: Animals, Apoptosis Regulatory Proteins, Cell Differentiation, Cell Transformation, Neoplastic, Coculture Techniques, Lymphoma, B-Cell, Mice, Mice, Knockout, Stem Cells, Stromal Cells, T-Lymphocytes, bcl-2 Homologous Antagonist-Killer Protein, bcl-2-Associated X Protein
Added September 7, 2011
1 Communities
3 Members
0 Resources
13 MeSH Terms
Betulin induces mitochondrial cytochrome c release associated apoptosis in human cancer cells.
Li Y, He K, Huang Y, Zheng D, Gao C, Cui L, Jin YH
(2010) Mol Carcinog 49: 630-40
MeSH Terms: Antineoplastic Agents, Phytogenic, Apoptosis, Apoptosis Regulatory Proteins, Caspase 3, Caspase 7, Caspase 9, Cell Line, Tumor, Cell Survival, Cytochromes c, HeLa Cells, Hep G2 Cells, Humans, Intracellular Signaling Peptides and Proteins, K562 Cells, Mitochondria, Mitochondrial Proteins, Neoplasms, Triterpenes, bcl-2 Homologous Antagonist-Killer Protein, bcl-2-Associated X Protein
Added July 28, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Specific mitochondrial calcium overload induces mitochondrial fission in prostate cancer cells.
Kaddour-Djebbar I, Choudhary V, Brooks C, Ghazaly T, Lakshmikanthan V, Dong Z, Kumar MV
(2010) Int J Oncol 36: 1437-44
MeSH Terms: Apoptosis, Blotting, Western, Calcium, Cell Line, Tumor, Clonazepam, Dynamins, GTP Phosphohydrolases, Humans, Immunohistochemistry, Immunoprecipitation, Male, Membrane Proteins, Microscopy, Electron, Transmission, Microtubule-Associated Proteins, Mitochondria, Mitochondrial Proteins, Prostatic Neoplasms, Sodium-Calcium Exchanger, TNF-Related Apoptosis-Inducing Ligand, Thiazepines, Transfection, bcl-2 Homologous Antagonist-Killer Protein
Added September 12, 2016
0 Communities
1 Members
0 Resources
22 MeSH Terms
The C-terminus of interferon gamma receptor beta chain (IFNgammaR2) has antiapoptotic activity as a Bax inhibitor.
Gomez JA, Sun W, Gama V, Hajkova D, Yoshida T, Wu Z, Miyagi M, Pink JJ, Jackson MW, Danielpour D, Matsuyama S
(2009) Cancer Biol Ther 8: 1771-86
MeSH Terms: Apoptosis, Apoptosis Regulatory Proteins, Bcl-2-Like Protein 11, Binding Sites, Blotting, Western, Cell Line, Cell Line, Tumor, Cell Membrane, Cytosol, Green Fluorescent Proteins, HeLa Cells, Humans, Immunoprecipitation, Janus Kinase 2, Mass Spectrometry, Membrane Proteins, Microscopy, Fluorescence, Mitochondria, Protein Binding, Proto-Oncogene Proteins, RNA Interference, Receptors, Interferon, STAT1 Transcription Factor, Signal Transduction, Transfection, Yeasts, bcl-2 Homologous Antagonist-Killer Protein, bcl-2-Associated X Protein
Added October 26, 2015
0 Communities
1 Members
0 Resources
28 MeSH Terms
Selective roles for antiapoptotic MCL-1 during granulocyte development and macrophage effector function.
Steimer DA, Boyd K, Takeuchi O, Fisher JK, Zambetti GP, Opferman JT
(2009) Blood 113: 2805-15
MeSH Terms: Animals, Apoptosis, Apoptosis Regulatory Proteins, Bcl-2-Like Protein 11, Bone Marrow Cells, Escherichia coli, Filgrastim, Gene Deletion, Granulocyte Colony-Stimulating Factor, Granulocytes, Macrophage Activation, Macrophages, Peritoneal, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Myeloid Cell Leukemia Sequence 1 Protein, Myelopoiesis, Organ Specificity, Phagocytosis, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-bcl-2, Recombinant Proteins, Specific Pathogen-Free Organisms, Tumor Suppressor Proteins, bcl-2 Homologous Antagonist-Killer Protein, bcl-2-Associated X Protein
Added March 5, 2014
0 Communities
1 Members
0 Resources
27 MeSH Terms
Regulation of mitochondrial morphological dynamics during apoptosis by Bcl-2 family proteins: a key in Bak?
Brooks C, Dong Z
(2007) Cell Cycle 6: 3043-7
MeSH Terms: Animals, Apoptosis, Humans, Membrane Fusion, Mitochondria, Mitochondrial Membranes, bcl-2 Homologous Antagonist-Killer Protein, bcl-2-Associated X Protein
Added September 12, 2016
0 Communities
1 Members
0 Resources
8 MeSH Terms
Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins.
Brooks C, Wei Q, Feng L, Dong G, Tao Y, Mei L, Xie ZJ, Dong Z
(2007) Proc Natl Acad Sci U S A 104: 11649-54
MeSH Terms: Animals, Animals, Newborn, Apoptosis, Cells, Cultured, GTP Phosphohydrolases, HeLa Cells, Humans, Intracellular Membranes, Mice, Mitochondria, Permeability, bcl-2 Homologous Antagonist-Killer Protein, bcl-2-Associated X Protein
Added September 12, 2016
0 Communities
1 Members
0 Resources
13 MeSH Terms