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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 6 of 6

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T cells from patients with Parkinson's disease recognize α-synuclein peptides.
Sulzer D, Alcalay RN, Garretti F, Cote L, Kanter E, Agin-Liebes J, Liong C, McMurtrey C, Hildebrand WH, Mao X, Dawson VL, Dawson TM, Oseroff C, Pham J, Sidney J, Dillon MB, Carpenter C, Weiskopf D, Phillips E, Mallal S, Peters B, Frazier A, Lindestam Arlehamn CS, Sette A
(2017) Nature 546: 656-661
MeSH Terms: Aged, Aged, 80 and over, Alleles, Amino Acid Sequence, Autoimmunity, Epitopes, T-Lymphocyte, Female, HLA Antigens, Humans, Male, Middle Aged, Parkinson Disease, Peptide Fragments, T-Lymphocytes, T-Lymphocytes, Cytotoxic, T-Lymphocytes, Helper-Inducer, alpha-Synuclein
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.
Edwards TL, Scott WK, Almonte C, Burt A, Powell EH, Beecham GW, Wang L, Züchner S, Konidari I, Wang G, Singer C, Nahab F, Scott B, Stajich JM, Pericak-Vance M, Haines J, Vance JM, Martin ER
(2010) Ann Hum Genet 74: 97-109
MeSH Terms: Genome-Wide Association Study, Humans, Parkinson Disease, Polymorphism, Single Nucleotide, alpha-Synuclein, tau Proteins
Added March 5, 2014
0 Communities
1 Members
0 Resources
6 MeSH Terms
Lipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with alpha-synuclein genotype.
Rappley I, Myers DS, Milne SB, Ivanova PT, Lavoie MJ, Brown HA, Selkoe DJ
(2009) J Neurochem 111: 15-25
MeSH Terms: Age Factors, Analysis of Variance, Animals, Brain, Female, Gene Dosage, Glycerophospholipids, Humans, Male, Mass Spectrometry, Metabolome, Mice, Mice, Inbred DBA, Mice, Transgenic, Principal Component Analysis, Sex Factors, alpha-Synuclein
Added March 21, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Evidence that alpha-synuclein does not inhibit phospholipase D.
Rappley I, Gitler AD, Selvy PE, LaVoie MJ, Levy BD, Brown HA, Lindquist S, Selkoe DJ
(2009) Biochemistry 48: 1077-83
MeSH Terms: Animals, Cell Line, Endoplasmic Reticulum, Genetic Vectors, HeLa Cells, Humans, PC12 Cells, Phospholipase D, Rats, Saccharomyces cerevisiae, Stress, Physiological, Transfection, alpha-Synuclein
Added March 21, 2013
0 Communities
1 Members
0 Resources
13 MeSH Terms
Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein.
Lakso M, Vartiainen S, Moilanen AM, Sirviö J, Thomas JH, Nass R, Blakely RD, Wong G
(2003) J Neurochem 86: 165-72
MeSH Terms: Animals, Animals, Genetically Modified, Behavior, Animal, Biological Assay, Caenorhabditis elegans, Cell Count, Disease Models, Animal, Dopamine, Genes, Reporter, Humans, Motor Activity, Nerve Tissue Proteins, Neurodegenerative Diseases, Neurons, Synucleins, alpha-Synuclein
Added July 10, 2013
1 Communities
1 Members
0 Resources
16 MeSH Terms
Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy.
Duda JE, Giasson BI, Gur TL, Montine TJ, Robertson D, Biaggioni I, Hurtig HI, Stern MB, Gollomp SM, Grossman M, Lee VM, Trojanowski JQ
(2000) J Neuropathol Exp Neurol 59: 830-41
MeSH Terms: Aged, Aged, 80 and over, Antibodies, Antibodies, Monoclonal, Basal Ganglia, Brain, Cerebellum, Female, Hippocampus, Humans, Immunohistochemistry, Male, Medulla Oblongata, Mesencephalon, Middle Aged, Multiple System Atrophy, Nerve Tissue Proteins, Pons, Synucleins, alpha-Synuclein
Added December 10, 2013
0 Communities
1 Members
0 Resources
20 MeSH Terms