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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 9 of 9

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Cleavage C-terminal to Asp leads to covalent crosslinking of long-lived human proteins.
Wang Z, Friedrich MG, Truscott RJW, Schey KL
(2019) Biochim Biophys Acta Proteins Proteom 1867: 831-839
MeSH Terms: Aquaporins, Aspartic Acid, Eye Proteins, Humans, Hydrogen-Ion Concentration, Lens, Crystalline, Models, Molecular, Peptides, alpha-Crystallin A Chain, alpha-Crystallin B Chain
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
A specific phosphorylation regulates the protective role of αA-crystallin in diabetes.
Ruebsam A, Dulle JE, Myers AM, Sakrikar D, Green KM, Khan NW, Schey K, Fort PE
(2018) JCI Insight 3:
MeSH Terms: Aged, Animals, Cell Line, Crystallins, Diabetes Mellitus, Experimental, Diabetic Retinopathy, Electroretinography, Ependymoglial Cells, Female, Humans, Male, Mice, Mice, Knockout, Neurons, Phosphorylation, Rats, Rats, Sprague-Dawley, Recombinant Proteins, Retina, Streptozocin, Transfection, alpha-Crystallin A Chain, alpha-Crystallin B Chain
Added April 3, 2018
0 Communities
1 Members
0 Resources
23 MeSH Terms
Loss of αB-crystallin function in zebrafish reveals critical roles in the development of the lens and stress resistance of the heart.
Mishra S, Wu SY, Fuller AW, Wang Z, Rose KL, Schey KL, Mchaourab HS
(2018) J Biol Chem 293: 740-753
MeSH Terms: Animals, Cardiomyopathies, Edema, Glucocorticoids, Image Processing, Computer-Assisted, Lens, Crystalline, Molecular Chaperones, Mutation, Myocardium, Pericardium, Phenotype, Receptors, Glucocorticoid, Signal Transduction, Stress, Physiological, Transgenes, Zebrafish, alpha-Crystallin A Chain, alpha-Crystallin B Chain
Added April 3, 2018
0 Communities
1 Members
0 Resources
18 MeSH Terms
Expression of Cataract-linked γ-Crystallin Variants in Zebrafish Reveals a Proteostasis Network That Senses Protein Stability.
Wu SY, Zou P, Fuller AW, Mishra S, Wang Z, Schey KL, Mchaourab HS
(2016) J Biol Chem 291: 25387-25397
MeSH Terms: Animals, Cataract, Lens Capsule, Crystalline, Mice, Mutation, Protein Aggregates, Zebrafish, Zebrafish Proteins, alpha-Crystallin A Chain, gamma-Crystallins
Added May 6, 2017
0 Communities
1 Members
0 Resources
10 MeSH Terms
A conserved role of αA-crystallin in the development of the zebrafish embryonic lens.
Zou P, Wu SY, Koteiche HA, Mishra S, Levic DS, Knapik E, Chen W, Mchaourab HS
(2015) Exp Eye Res 138: 104-13
MeSH Terms: Animals, Animals, Genetically Modified, Blotting, Western, Electrophoresis, Polyacrylamide Gel, Embryo, Nonmammalian, Gene Expression Regulation, Developmental, Gene Knockout Techniques, Lens, Crystalline, Real-Time Polymerase Chain Reaction, Zebrafish, alpha-Crystallin A Chain
Added July 23, 2015
1 Communities
2 Members
0 Resources
11 MeSH Terms
Tissue localization and solubilities of αA-crystallin and its numerous C-terminal truncation products in pre- and postcataractous ICR/f rat lenses.
Stella DR, Floyd KA, Grey AC, Renfrow MB, Schey KL, Barnes S
(2010) Invest Ophthalmol Vis Sci 51: 5153-61
MeSH Terms: Animals, Cataract, Chromatography, High Pressure Liquid, Disease Models, Animal, Fourier Analysis, Lens, Crystalline, Peptide Fragments, Proteomics, Rats, Rats, Wistar, Solubility, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Tissue Distribution, alpha-Crystallin A Chain
Added May 27, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Age-related changes in the spatial distribution of human lens alpha-crystallin products by MALDI imaging mass spectrometry.
Grey AC, Schey KL
(2009) Invest Ophthalmol Vis Sci 50: 4319-29
MeSH Terms: Adult, Aged, Aging, Blotting, Western, Cataract, Child, Electrophoresis, Polyacrylamide Gel, Humans, Lens, Crystalline, Middle Aged, Protein Processing, Post-Translational, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, alpha-Crystallin A Chain, alpha-Crystallin B Chain
Added May 27, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
De novo high-resolution protein structure determination from sparse spin-labeling EPR data.
Alexander N, Bortolus M, Al-Mestarihi A, Mchaourab H, Meiler J
(2008) Structure 16: 181-95
MeSH Terms: Algorithms, Electron Spin Resonance Spectroscopy, Linear Models, Models, Molecular, Muramidase, Protein Conformation, Protein Folding, Spin Labels, alpha-Crystallin A Chain
Added January 24, 2015
1 Communities
1 Members
0 Resources
9 MeSH Terms
MALDI tissue imaging of ocular lens alpha-crystallin.
Han J, Schey KL
(2006) Invest Ophthalmol Vis Sci 47: 2990-6
MeSH Terms: Animals, Cattle, Chromatography, High Pressure Liquid, Lens, Crystalline, Phosphorylation, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, alpha-Crystallin A Chain, alpha-Crystallin B Chain
Added May 27, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms