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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 7 of 7

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Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion.
Syring KE, Boortz KA, Oeser JK, Ustione A, Platt KA, Shadoan MK, McGuinness OP, Piston DW, Powell DR, O'Brien RM
(2016) Endocrinology 157: 4534-4541
MeSH Terms: Animals, Body Weight, Cation Transport Proteins, Female, Glucagon-Secreting Cells, Glucose, Glucose Intolerance, Insulin, Insulin Secretion, Insulin-Secreting Cells, Islets of Langerhans, Male, Mice, Mice, Knockout, Sex Factors, Zinc Transporter 8
Added March 14, 2018
0 Communities
1 Members
0 Resources
16 MeSH Terms
SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity.
Leyva-Illades D, Chen P, Zogzas CE, Hutchens S, Mercado JM, Swaim CD, Morrisett RA, Bowman AB, Aschner M, Mukhopadhyay S
(2014) J Neurosci 34: 14079-95
MeSH Terms: Animals, Caenorhabditis elegans, Cation Transport Proteins, Cell Membrane, Cells, Cultured, Female, HeLa Cells, Humans, Intracellular Fluid, Male, Manganese, Mice, Inbred C57BL, Mutation, Parkinsonian Disorders, Protein Transport, Zinc Transporter 8
Added February 3, 2015
1 Communities
1 Members
0 Resources
16 MeSH Terms
The physiological effects of deleting the mouse SLC30A8 gene encoding zinc transporter-8 are influenced by gender and genetic background.
Pound LD, Sarkar SA, Ustione A, Dadi PK, Shadoan MK, Lee CE, Walters JA, Shiota M, McGuinness OP, Jacobson DA, Piston DW, Hutton JC, Powell DR, O'Brien RM
(2012) PLoS One 7: e40972
MeSH Terms: Animals, Blood Glucose, Cation Transport Proteins, Fasting, Female, Glucose Intolerance, Insulin, Islets of Langerhans, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Sex Factors, Zinc, Zinc Transporter 8
Added December 10, 2013
4 Communities
5 Members
1 Resources
15 MeSH Terms
Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies.
Yu L, Boulware DC, Beam CA, Hutton JC, Wenzlau JM, Greenbaum CJ, Bingley PJ, Krischer JP, Sosenko JM, Skyler JS, Eisenbarth GS, Mahon JL, Type 1 Diabetes TrialNet Study Group
(2012) Diabetes Care 35: 1213-8
MeSH Terms: Adolescent, Adult, Autoantibodies, Cation Transport Proteins, Child, Child, Preschool, Cohort Studies, Diabetes Mellitus, Type 1, Family, Female, Genotype, Glucose Tolerance Test, Humans, Infant, Male, Middle Aged, Predictive Value of Tests, Risk Assessment, Risk Factors, Young Adult, Zinc Transporter 8
Added October 24, 2013
0 Communities
1 Members
0 Resources
21 MeSH Terms
Characterization of the human SLC30A8 promoter and intronic enhancer.
Pound LD, Sarkar SA, Cauchi S, Wang Y, Oeser JK, Lee CE, Froguel P, Hutton JC, O'Brien RM
(2011) J Mol Endocrinol 47: 251-9
MeSH Terms: Animals, Cation Transport Proteins, Cells, Cultured, Conserved Sequence, Diabetes Mellitus, Type 2, Enhancer Elements, Genetic, Gene Expression Regulation, Genes, Reporter, Glucagon-Secreting Cells, Humans, Insulin-Secreting Cells, Introns, Mice, Promoter Regions, Genetic, Transcriptional Activation, Transfection, Zinc Transporter 8
Added July 30, 2015
0 Communities
0 Members
1 Resources
17 MeSH Terms
The pancreatic islet β-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer.
Pound LD, Hang Y, Sarkar SA, Wang Y, Milam LA, Oeser JK, Printz RL, Lee CE, Stein R, Hutton JC, O'Brien RM
(2011) Biochem J 433: 95-105
MeSH Terms: Animals, Binding Sites, Cation Transport Proteins, Enhancer Elements, Genetic, Gene Expression Regulation, Homeodomain Proteins, Introns, Islets of Langerhans, Mice, Tissue Distribution, Trans-Activators, Transcription Factors, Transcription, Genetic, Zinc Transporter 8
Added March 7, 2014
1 Communities
1 Members
1 Resources
14 MeSH Terms
Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion.
Pound LD, Sarkar SA, Benninger RK, Wang Y, Suwanichkul A, Shadoan MK, Printz RL, Oeser JK, Lee CE, Piston DW, McGuinness OP, Hutton JC, Powell DR, O'Brien RM
(2009) Biochem J 421: 371-6
MeSH Terms: Animals, Blood Glucose, Cation Transport Proteins, Diabetes Mellitus, Female, Glucose Tolerance Test, Humans, Insulin, Insulin Secretion, Islets of Langerhans, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Sequence Deletion, Zinc, Zinc Transporter 8
Added December 10, 2013
0 Communities
2 Members
1 Resources
17 MeSH Terms