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Inefficient ZAP-70 phosphorylation and decreased thymic selection in vivo result from inhibition of NF-kappaB/Rel.
Mora AL, Stanley S, Armistead W, Chan AC, Boothby M
(2001) J Immunol 167: 5628-35
MeSH Terms: Animals, Cell Survival, Cells, Cultured, Clonal Deletion, DNA-Binding Proteins, Female, I-kappa B Proteins, Mice, Mice, Transgenic, NF-KappaB Inhibitor alpha, NF-kappa B, Phosphorylation, Protein-Tyrosine Kinases, Proto-Oncogene Proteins c-rel, Receptors, Antigen, T-Cell, Signal Transduction, T-Lymphocytes, Thymus Gland, ZAP-70 Protein-Tyrosine Kinase
Added December 10, 2013
0 Communities
1 Members
0 Resources
19 MeSH Terms
ZAP-70 tyrosine kinase is required for the up-regulation of Fas ligand in activation-induced T cell apoptosis.
Eischen CM, Williams BL, Zhang W, Samelson LE, Lynch DH, Abraham RT, Leibson PJ
(1997) J Immunol 159: 1135-9
MeSH Terms: Apoptosis, Fas Ligand Protein, Humans, Jurkat Cells, Ligands, Lymphocyte Activation, Membrane Glycoproteins, Protein-Tyrosine Kinases, RNA, Messenger, Receptors, Antigen, T-Cell, T-Lymphocytes, Up-Regulation, ZAP-70 Protein-Tyrosine Kinase, fas Receptor
Added March 5, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms