Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 13

Publication Record

Connections

Structure-Activity Relationships, Pharmacokinetics, and Pharmacodynamics of the Kir6.2/SUR1-Specific Channel Opener VU0071063.
Kharade SV, Sanchez-Andres JV, Fulton MG, Shelton EL, Blobaum AL, Engers DW, Hofmann CS, Dadi PK, Lantier L, Jacobson DA, Lindsley CW, Denton JS
(2019) J Pharmacol Exp Ther 370: 350-359
MeSH Terms: Animals, Ductus Arteriosus, Glucose, HEK293 Cells, Humans, Insulin Secretion, Insulin-Secreting Cells, Ion Channel Gating, Mice, Potassium Channels, Inwardly Rectifying, Structure-Activity Relationship, Sulfonylurea Receptors, Vasodilation, Xanthines
Added June 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Direct activation of β-cell KATP channels with a novel xanthine derivative.
Raphemot R, Swale DR, Dadi PK, Jacobson DA, Cooper P, Wojtovich AP, Banerjee S, Nichols CG, Denton JS
(2014) Mol Pharmacol 85: 858-65
MeSH Terms: Glucose, HEK293 Cells, Humans, Ion Channel Gating, Islets of Langerhans, KATP Channels, Patch-Clamp Techniques, Structure-Activity Relationship, Sulfonylurea Receptors, Xanthine, Xanthines
Added February 12, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Effect of A2B adenosine receptor gene ablation on proinflammatory adenosine signaling in mast cells.
Ryzhov S, Zaynagetdinov R, Goldstein AE, Novitskiy SV, Dikov MM, Blackburn MR, Biaggioni I, Feoktistov I
(2008) J Immunol 180: 7212-20
MeSH Terms: Adenosine, Adenosine A2 Receptor Antagonists, Adenosine Monophosphate, Animals, Bone Marrow Cells, Cell Degranulation, Cell Line, Cells, Cultured, Extracellular Signal-Regulated MAP Kinases, Humans, Interleukin-13, Mast Cells, Mice, Mice, Inbred C57BL, Purines, Receptor, Adenosine A2B, Signal Transduction, Vascular Endothelial Growth Factor A, Xanthines, p38 Mitogen-Activated Protein Kinases
Added December 10, 2013
0 Communities
3 Members
0 Resources
20 MeSH Terms
Adenosine receptor antagonists and retinal neovascularization in vivo.
Mino RP, Spoerri PE, Caballero S, Player D, Belardinelli L, Biaggioni I, Grant MB
(2001) Invest Ophthalmol Vis Sci 42: 3320-4
MeSH Terms: Angiography, Animals, Animals, Newborn, Mice, Mice, Inbred C57BL, Neovascularization, Pathologic, Purinergic P1 Receptor Antagonists, Pyrrolidinones, Retina, Retinal Vessels, Xanthines
Added December 10, 2013
0 Communities
1 Members
0 Resources
11 MeSH Terms
Inhibition of human mast cell activation with the novel selective adenosine A(2B) receptor antagonist 3-isobutyl-8-pyrrolidinoxanthine (IPDX)(2).
Feoktistov I, Garland EM, Goldstein AE, Zeng D, Belardinelli L, Wells JN, Biaggioni I
(2001) Biochem Pharmacol 62: 1163-73
MeSH Terms: Adenosine, Adenosine-5'-(N-ethylcarboxamide), Anti-Asthmatic Agents, Cells, Cultured, Humans, Mast Cells, Purinergic P1 Receptor Antagonists, Pyrrolidinones, Receptor, Adenosine A2B, Receptors, Purinergic P1, Structure-Activity Relationship, Vasodilator Agents, Xanthine, Xanthines
Added December 10, 2013
0 Communities
2 Members
0 Resources
14 MeSH Terms
Role of adenosine in asthma.
Feoktistov I, Biaggioni I
(1996) Drug Dev Res 39: 333-6
MeSH Terms: Adenosine, Adrenergic beta-Antagonists, Animals, Anti-Asthmatic Agents, Asthma, Bronchoconstriction, Bronchodilator Agents, Dogs, Humans, Lung, Mast Cells, Mice, Rats, Receptors, Adrenergic, alpha-2, Receptors, Adrenergic, beta-2, Theophylline, Xanthines
Added December 10, 2013
0 Communities
2 Members
0 Resources
17 MeSH Terms
Inotropic effects of diadenosine tetraphosphate (AP4A) in human and animal cardiac preparations.
Vahlensieck U, Bokník P, Gombosová I, Huke S, Knapp J, Linck B, Lüss H, Müller FU, Neumann J, Deng MC, Scheld HH, Jankowski H, Schlüter H, Zidek W, Zimmermann N, Schmitz W
(1999) J Pharmacol Exp Ther 288: 805-13
MeSH Terms: Animals, Calcium, Calcium Channels, Cells, Cultured, Dinucleoside Phosphates, Drug Interactions, Guinea Pigs, Heart, Heart Atria, Heart Ventricles, Humans, In Vitro Techniques, Male, Myocardial Contraction, Myocardium, Platelet Aggregation Inhibitors, Xanthines
Added May 27, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Antagonists of the receptor-G protein interface block Gi-coupled signal transduction.
Gilchrist A, Mazzoni MR, Dineen B, Dice A, Linden J, Proctor WR, Lupica CR, Dunwiddie TV, Hamm HE
(1998) J Biol Chem 273: 14912-9
MeSH Terms: Adenosine, Animals, Baclofen, Binding, Competitive, Brain, Cells, Cultured, Electrophysiology, GTP-Binding Proteins, Humans, Male, Peptide Fragments, Rats, Rats, Sprague-Dawley, Receptors, GABA, Receptors, Purinergic P1, Rhodopsin, Signal Transduction, Xanthines
Added December 10, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma.
Feoktistov I, Biaggioni I
(1995) J Clin Invest 96: 1979-86
MeSH Terms: Adenosine, Adenosine-5'-(N-ethylcarboxamide), Anti-Asthmatic Agents, Asthma, Calcium, Cyclic AMP, Humans, Inositol Phosphates, Interleukin-8, Mast Cells, Receptors, Purinergic P1, Tumor Cells, Cultured, Xanthines
Added December 10, 2013
0 Communities
2 Members
0 Resources
13 MeSH Terms
Caffeine potentiates the renin response to furosemide in rats. Evidence for a regulatory role of endogenous adenosine.
Paul S, Jackson EK, Robertson D, Branch RA, Biaggioni I
(1989) J Pharmacol Exp Ther 251: 183-7
MeSH Terms: Adenosine, Animals, Caffeine, Drug Synergism, Furosemide, Kidney, Male, Rats, Rats, Inbred Strains, Renin, Xanthines
Added December 10, 2013
0 Communities
2 Members
0 Resources
11 MeSH Terms