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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 39

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Integrated analysis of genetic variation and gene expression reveals novel variant for increased warfarin dose requirement in African Americans.
Hernandez W, Gamazon ER, Aquino-Michaels K, Smithberger E, O'Brien TJ, Harralson AF, Tuck M, Barbour A, Cavallari LH, Perera MA
(2017) J Thromb Haemost 15: 735-743
MeSH Terms: Adult, African Americans, Aged, Algorithms, Calcium-Binding Proteins, Cohort Studies, Cytochrome P-450 CYP2C9, Female, Gene Expression Profiling, Gene Expression Regulation, Genetic Variation, Genotype, Humans, Linkage Disequilibrium, Liver, Male, Middle Aged, Pharmacogenetics, Precision Medicine, Quantitative Trait Loci, Thromboembolism, Vitamin K Epoxide Reductases, Warfarin
Added April 13, 2017
0 Communities
1 Members
0 Resources
23 MeSH Terms
Pharmacogenetic Implementation Lessons From the "Real World".
Roden DM
(2017) Clin Pharmacol Ther 102: 25-27
MeSH Terms: Algorithms, Anticoagulants, Humans, Pharmacogenetics, Pharmacogenomic Testing, Warfarin
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
STRATEGIES FOR EQUITABLE PHARMACOGENOMIC-GUIDED WARFARIN DOSING AMONG EUROPEAN AND AFRICAN AMERICAN INDIVIDUALS IN A CLINICAL POPULATION.
Wiley LK, Vanhouten JP, Samuels DC, Aldrich MC, Roden DM, Peterson JF, Denny JC
(2017) Pac Symp Biocomput 22: 545-556
MeSH Terms: Adult, African Americans, Aged, Algorithms, Anticoagulants, Cohort Studies, Computational Biology, Cytochrome P-450 CYP2C9, Female, Gene Frequency, Humans, Male, Middle Aged, Models, Genetic, Pharmacogenomic Variants, Polymorphism, Single Nucleotide, Vitamin K Epoxide Reductases, Warfarin, Whites
Added March 14, 2018
0 Communities
2 Members
0 Resources
19 MeSH Terms
Genetic determinants of variability in warfarin response after the dose-titration phase.
Iwuchukwu OF, Ramirez AH, Shi Y, Bowton EA, Kawai VK, Schildcrout JS, Roden DM, Denny JC, Stein CM
(2016) Pharmacogenet Genomics 26: 510-516
MeSH Terms: Adult, African Americans, Aged, Aged, 80 and over, Anticoagulants, Calcium-Binding Proteins, Carbon-Carbon Ligases, Cytochrome P-450 CYP2C9, Cytochrome P450 Family 4, Epoxide Hydrolases, Female, Humans, International Normalized Ratio, Male, Middle Aged, Pharmacogenomic Variants, Vitamin K Epoxide Reductases, Warfarin, Whites
Added March 14, 2018
0 Communities
2 Members
0 Resources
19 MeSH Terms
A prognostic model based on readily available clinical data enriched a pre-emptive pharmacogenetic testing program.
Schildcrout JS, Shi Y, Danciu I, Bowton E, Field JR, Pulley JM, Basford MA, Gregg W, Cowan JD, Harrell FE, Roden DM, Peterson JF, Denny JC
(2016) J Clin Epidemiol 72: 107-15
MeSH Terms: Adult, Age Factors, Aged, Clopidogrel, Decision Support Systems, Clinical, Drug Utilization, Electronic Health Records, Female, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Longitudinal Studies, Male, Middle Aged, Models, Statistical, Pharmacogenetics, Predictive Value of Tests, Prognosis, Program Evaluation, Proportional Hazards Models, Reproducibility of Results, Risk Factors, Sex Factors, Ticlopidine, United States, Warfarin
Added March 14, 2018
0 Communities
2 Members
0 Resources
25 MeSH Terms
Cardiovascular pharmacogenomics: current status and future directions.
Roden DM
(2016) J Hum Genet 61: 79-85
MeSH Terms: Arrhythmias, Cardiac, Cardiovascular Agents, Clopidogrel, Genetic Variation, Genomics, Hematologic Agents, Heparin, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Pharmacogenetics, Ticlopidine, Warfarin
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Genotype and risk of major bleeding during warfarin treatment.
Kawai VK, Cunningham A, Vear SI, Van Driest SL, Oginni A, Xu H, Jiang M, Li C, Denny JC, Shaffer C, Bowton E, Gage BF, Ray WA, Roden DM, Stein CM
(2014) Pharmacogenomics 15: 1973-83
MeSH Terms: Adult, Aged, Biological Specimen Banks, Cytochrome P-450 CYP2C9, Cytochrome P-450 Enzyme System, Cytochrome P450 Family 4, Dose-Response Relationship, Drug, Ethnicity, Female, Gene Frequency, Genetic Association Studies, Genetic Variation, Genotype, Hemorrhage, Humans, Male, Middle Aged, Risk Factors, Vitamin K Epoxide Reductases, Warfarin
Added January 23, 2015
0 Communities
4 Members
0 Resources
20 MeSH Terms
Genetic variant in folate homeostasis is associated with lower warfarin dose in African Americans.
Daneshjou R, Gamazon ER, Burkley B, Cavallari LH, Johnson JA, Klein TE, Limdi N, Hillenmeyer S, Percha B, Karczewski KJ, Langaee T, Patel SR, Bustamante CD, Altman RB, Perera MA
(2014) Blood 124: 2298-305
MeSH Terms: African Americans, Algorithms, Alleles, Anticoagulants, Cohort Studies, Exome, Folic Acid, Geography, Haplotypes, Homeostasis, Humans, Pharmacogenetics, Phenotype, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Sequence Analysis, DNA, Warfarin
Added April 13, 2017
0 Communities
1 Members
0 Resources
17 MeSH Terms
The impact of age and CYP2C9 and VKORC1 variants on stable warfarin dose in the paediatric population.
Vear SI, Ayers GD, Van Driest SL, Sidonio RF, Stein CM, Ho RH
(2014) Br J Haematol 165: 832-5
MeSH Terms: Adolescent, Age Factors, Alleles, Anticoagulants, Aryl Hydrocarbon Hydroxylases, Child, Child, Preschool, Cross-Sectional Studies, Cytochrome P-450 CYP2C9, Genetic Variation, Genotype, Humans, Infant, Pharmacogenetics, Retrospective Studies, Vitamin K Epoxide Reductases, Warfarin
Added March 10, 2014
1 Communities
3 Members
0 Resources
17 MeSH Terms
Pulmonary embolism after total joint arthroplasty: cost and effectiveness of four treatment modalities.
Raphael IJ, McKenzie JC, Zmistowski B, Brown DB, Parvizi J, Austin MS
(2014) J Arthroplasty 29: 933-7
MeSH Terms: Aged, Aged, 80 and over, Anticoagulants, Arthroplasty, Replacement, Costs and Cost Analysis, Female, Heparin, Humans, Male, Middle Aged, Pulmonary Embolism, Retrospective Studies, Treatment Outcome, Vena Cava Filters, Warfarin
Added March 5, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms