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Results: 1 to 10 of 40

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Current Understanding of Humoral Immunity to Enterovirus D68.
Vogt MR, Crowe JE
(2018) J Pediatric Infect Dis Soc 7: S49-S53
MeSH Terms: Animals, Antibodies, Neutralizing, Disease Models, Animal, Enterovirus D, Human, Enterovirus Infections, Epitopes, Humans, Immunity, Humoral, Nervous System Diseases, Respiratory Tract Infections, Seroepidemiologic Studies, Vaccination, Viral Vaccines
Added March 31, 2019
0 Communities
1 Members
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MeSH Terms
Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vectored Ebolavirus Vaccine.
Kimble JB, Malherbe DC, Meyer M, Gunn BM, Karim MM, Ilinykh PA, Iampietro M, Mohamed KS, Negi S, Gilchuk P, Huang K, Wolf YI, Braun W, Crowe JE, Alter G, Bukreyev A
(2019) J Virol 93:
MeSH Terms: Animals, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Cell Line, Drug Combinations, Ebola Vaccines, Ebolavirus, Epitopes, Female, Ferrets, Genetic Vectors, Glycoproteins, Guinea Pigs, Hemorrhagic Fever, Ebola, Parainfluenza Virus 3, Human, Viral Envelope Proteins, Viral Vaccines
Added March 31, 2019
0 Communities
1 Members
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18 MeSH Terms
Mapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to Dengue Virus Serotype 4 Infection and Vaccination.
Nivarthi UK, Kose N, Sapparapu G, Widman D, Gallichotte E, Pfaff JM, Doranz BJ, Weiskopf D, Sette A, Durbin AP, Whitehead SS, Baric R, Crowe JE, de Silva AM
(2017) J Virol 91:
MeSH Terms: Adaptive Immunity, Aedes, Animals, Antibodies, Neutralizing, Antibodies, Viral, B-Lymphocytes, Cell Line, Dengue, Dengue Virus, Epitope Mapping, Humans, Immunologic Memory, Protein Binding, Protein Domains, Vaccination, Vaccines, Attenuated, Viral Vaccines
Added April 13, 2017
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17 MeSH Terms
Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice.
Sapparapu G, Fernandez E, Kose N, Bin Cao , Fox JM, Bombardi RG, Zhao H, Nelson CA, Bryan AL, Barnes T, Davidson E, Mysorekar IU, Fremont DH, Doranz BJ, Diamond MS, Crowe JE
(2016) Nature 540: 443-447
MeSH Terms: Africa, Americas, Animals, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Antibody Specificity, Asia, B-Lymphocytes, Disease Models, Animal, Epitope Mapping, Female, Fetal Diseases, Fetus, Humans, Infectious Disease Transmission, Vertical, Male, Mice, Models, Molecular, Placenta, Pregnancy, Protein Multimerization, Survival Rate, Viral Proteins, Viral Vaccines, Virus Replication, Zika Virus, Zika Virus Infection
Added April 13, 2017
0 Communities
1 Members
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28 MeSH Terms
Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Joyce MG, Zhang B, Ou L, Chen M, Chuang GY, Druz A, Kong WP, Lai YT, Rundlet EJ, Tsybovsky Y, Yang Y, Georgiev IS, Guttman M, Lees CR, Pancera M, Sastry M, Soto C, Stewart-Jones GBE, Thomas PV, Van Galen JG, Baxa U, Lee KK, Mascola JR, Graham BS, Kwong PD
(2016) Nat Struct Mol Biol 23: 811-820
MeSH Terms: Animals, Crystallography, X-Ray, Female, Glycoproteins, HEK293 Cells, Humans, Male, Mice, Inbred C57BL, Models, Molecular, Protein Engineering, Protein Stability, Respiratory Syncytial Virus Infections, Respiratory Syncytial Viruses, Vaccination, Viral Fusion Proteins, Viral Vaccines
Added May 3, 2017
0 Communities
1 Members
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16 MeSH Terms
Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus.
Boyington JC, Joyce MG, Sastry M, Stewart-Jones GB, Chen M, Kong WP, Ngwuta JO, Thomas PV, Tsybovsky Y, Yang Y, Zhang B, Chen L, Druz A, Georgiev IS, Ko K, Zhou T, Mascola JR, Graham BS, Kwong PD
(2016) PLoS One 11: e0159709
MeSH Terms: Animals, Antibodies, Viral, Female, HEK293 Cells, Humans, Immunogenicity, Vaccine, Male, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Protein Conformation, Respiratory Syncytial Viruses, Viral Fusion Proteins, Viral Vaccines
Added May 3, 2017
0 Communities
1 Members
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14 MeSH Terms
Immunogenicity and efficacy of alphavirus-derived replicon vaccines for respiratory syncytial virus and human metapneumovirus in nonhuman primates.
Bates JT, Pickens JA, Schuster JE, Johnson M, Tollefson SJ, Williams JV, Davis NL, Johnston RE, Schultz-Darken N, Slaughter JC, Smith-House F, Crowe JE
(2016) Vaccine 34: 950-6
MeSH Terms: Alphavirus, Animals, Antibodies, Neutralizing, Antibodies, Viral, Bronchoalveolar Lavage Fluid, Chlorocebus aethiops, Encephalitis Virus, Venezuelan Equine, Immunoglobulin G, Metapneumovirus, Neutralization Tests, Nose, Paramyxoviridae Infections, Replicon, Respiratory Syncytial Virus Infections, Respiratory Syncytial Virus, Human, Viral Fusion Proteins, Viral Vaccines
Added January 26, 2016
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17 MeSH Terms
Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.
Fox JM, Long F, Edeling MA, Lin H, van Duijl-Richter MKS, Fong RH, Kahle KM, Smit JM, Jin J, Simmons G, Doranz BJ, Crowe JE, Fremont DH, Rossmann MG, Diamond MS
(2015) Cell 163: 1095-1107
MeSH Terms: Alphavirus, Alphavirus Infections, Amino Acid Sequence, Animals, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Chikungunya virus, Cryoelectron Microscopy, Epitopes, Glycoproteins, Humans, Immunoglobulin Fab Fragments, Mice, Models, Molecular, Molecular Sequence Data, Protein Structure, Tertiary, Sequence Alignment, Viral Envelope Proteins, Viral Vaccines, Virus Internalization
Added January 26, 2016
0 Communities
1 Members
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21 MeSH Terms
Evaluation of candidate vaccine approaches for MERS-CoV.
Wang L, Shi W, Joyce MG, Modjarrad K, Zhang Y, Leung K, Lees CR, Zhou T, Yassine HM, Kanekiyo M, Yang ZY, Chen X, Becker MM, Freeman M, Vogel L, Johnson JC, Olinger G, Todd JP, Bagci U, Solomon J, Mollura DJ, Hensley L, Jahrling P, Denison MR, Rao SS, Subbarao K, Kwong PD, Mascola JR, Kong WP, Graham BS
(2015) Nat Commun 6: 7712
MeSH Terms: Animals, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Coronavirus Infections, DNA, Viral, Female, HEK293 Cells, Humans, Immunoglobulin G, Macaca mulatta, Male, Mice, Mice, Inbred BALB C, Middle East Respiratory Syndrome Coronavirus, Spike Glycoprotein, Coronavirus, Vaccines, DNA, Viral Vaccines
Added February 22, 2016
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18 MeSH Terms
A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant.
Agnihothram S, Yount BL, Donaldson EF, Huynh J, Menachery VD, Gralinski LE, Graham RL, Becker MM, Tomar S, Scobey TD, Osswald HL, Whitmore A, Gopal R, Ghosh AK, Mesecar A, Zambon M, Heise M, Denison MR, Baric RS
(2014) mBio 5: e00047-14
MeSH Terms: Animals, Chiroptera, Coronavirus, Coronavirus Infections, Disease Models, Animal, Drug Carriers, Encephalitis Virus, Venezuelan Equine, Eosinophilia, Genetic Vectors, Mice, Mice, Inbred BALB C, Respiratory System, Vaccines, Synthetic, Viral Vaccines
Added February 19, 2015
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1 Members
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14 MeSH Terms