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Results: 1 to 4 of 4

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Residue 82 of the Chikungunya virus E2 attachment protein modulates viral dissemination and arthritis in mice.
Ashbrook AW, Burrack KS, Silva LA, Montgomery SA, Heise MT, Morrison TE, Dermody TS
(2014) J Virol 88: 12180-92
MeSH Terms: Amino Acid Substitution, Animals, Arthritis, CHO Cells, Chikungunya virus, Cricetulus, Disease Models, Animal, Mice, Inbred C57BL, Mutant Proteins, Viral Envelope Proteins, Viral Tropism, Virulence Factors, Virus Replication
Added January 21, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
An ITAM in a nonenveloped virus regulates activation of NF-κB, induction of beta interferon, and viral spread.
Stebbing RE, Irvin SC, Rivera-Serrano EE, Boehme KW, Ikizler M, Yoder JA, Dermody TS, Sherry B
(2014) J Virol 88: 2572-83
MeSH Terms: Amino Acid Sequence, Animals, Cell Line, Enzyme Activation, Humans, Immunoreceptor Tyrosine-Based Activation Motif, Interferon-beta, Intracellular Signaling Peptides and Proteins, Mice, Molecular Sequence Data, Myocytes, Cardiac, NF-kappa B, Phosphorylation, Protein Binding, Protein-Tyrosine Kinases, Reoviridae, Sequence Alignment, Syk Kinase, Tyrosine, Viral Proteins, Viral Tropism
Added May 20, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Reovirus replication protein μ2 influences cell tropism by promoting particle assembly within viral inclusions.
Ooms LS, Jerome WG, Dermody TS, Chappell JD
(2012) J Virol 86: 10979-87
MeSH Terms: Animals, Cell Line, Dogs, Inclusion Bodies, Viral, Madin Darby Canine Kidney Cells, Mice, Microscopy, Electron, Transmission, Phenotype, RNA, Double-Stranded, RNA, Viral, Reoviridae, Temperature, Viral Nonstructural Proteins, Viral Proteins, Viral Tropism, Virus Assembly, Virus Replication
Added December 10, 2013
1 Communities
2 Members
0 Resources
17 MeSH Terms
A post-entry step in the mammalian orthoreovirus replication cycle is a determinant of cell tropism.
Ooms LS, Kobayashi T, Dermody TS, Chappell JD
(2010) J Biol Chem 285: 41604-13
MeSH Terms: Animals, Cell Line, Chick Embryo, DNA-Directed RNA Polymerases, Dogs, Models, Genetic, Molecular Sequence Data, Mutation, RNA, Double-Stranded, RNA, Viral, Reoviridae, Reverse Transcriptase Polymerase Chain Reaction, Viral Tropism, Virus Replication
Added December 10, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms